Tetrafol Plus Tablet (10 Tab)

TETRAFOL PLUS TABLET (10 TAB) by SUN PHARMA LABORATORIES LTD.

TETRAFOL PLUS TABLET is a comprehensive nutritional supplement formulated to support overall health and well-being. Manufactured by SUN PHARMA LABORATORIES LTD., it is designed to address specific nutritional needs, particularly concerning nerve function, red blood cell formation, and energy production.

Composition

TETRAFOL PLUS TABLET contains a synergistic blend of active forms of essential B vitamins:

• L-Methylfolate (L-5-Methyltetrahydrofolate Calcium): The active form of folic acid, crucial for cell growth, DNA synthesis, and red blood cell formation. It is readily utilized by the body without enzymatic conversion, which is beneficial for individuals with MTHFR gene mutations.
• Methylcobalamin (Mecobalamin): An active form of Vitamin B12, vital for nerve function, brain health, red blood cell production, and DNA synthesis.
• Pyridoxal-5-Phosphate (P5P): The active form of Vitamin B6, essential for various metabolic processes, including protein metabolism, neurotransmitter synthesis, and regulating homocysteine levels. Some formulations may also include Vitamin D3, which supports calcium absorption, bone health, and immune function.

Uses

TETRAFOL PLUS TABLET is prescribed for the prevention, treatment, and improvement of various conditions, including:

• Folic acid deficiency and certain types of anemia, such as megaloblastic and pregnancy-related anemia.
• Prevention of neural tube defects (NTDs) in a baby during pregnancy.
• Support for healthy nerve function, brain health, and management of nerve pain, particularly in diabetic peripheral neuropathy.
• Reduction of high homocysteine levels, which are associated with pregnancy complications and cardiovascular health.
• Addressing general nutritional deficiencies, fatigue, weakness, and supporting overall cognitive function.

Dosage and Administration

Take TETRAFOL PLUS TABLET as advised by your physician, typically once or twice daily with water, preferably with a meal. Do not exceed the recommended dosage, and refrain from self-medication.

Side Effects

Common side effects may include:

• Nausea, vomiting, abdominal pain, loss of appetite, and mild diarrhea.
• Allergic reactions, skin reactions (itching, redness, rashes, hives), and light sensitivity.
• Tingling or pricking sensation, sleepiness, and headaches. In rare cases, more serious side effects such as polycythemia vera have been reported. Consult your doctor if any side effects worsen or persist.

Precautions

• Inform your doctor about any existing medical conditions (e.g., diabetes, hypertension, kidney or liver problems), other medications, or supplements you are taking.
• Pregnant and breastfeeding women should use TETRAFOL PLUS TABLET with caution and under medical supervision.
• Avoid smoking and alcohol consumption during treatment.
• Exercise caution when driving or operating machinery if the medicine affects mental alertness or motor coordination.
• The safety and effectiveness in children have not been established without doctor consultation.
• This supplement can interact with certain medications, including anticonvulsants, some antibiotics, and warfarin.

Storage

Store TETRAFOL PLUS TABLET in a cool, dry place at room temperature (20-25°C), protected from heat, direct sunlight, and moisture. Keep it out of reach of children and pets.

What is TETRAFOL PLUS TABLET used for?

TETRAFOL PLUS TABLET is primarily used to address nutritional deficiencies, particularly those involving folic acid (Vitamin B9), Vitamin B12, and Vitamin B6. It is prescribed for the treatment and management of certain types of anemia caused by low folate levels, and to support the healthy functioning of nerves and the brain. Additionally, it plays a crucial role in preventing brain, spinal cord, or spine defects (neural tube defects) in a baby during pregnancy and helps reduce high levels of homocysteine, an amino acid linked to pregnancy complications. The medicine is also used to manage endothelial dysfunction, hyperhomocysteinemia, and to protect nerve cells in diabetic peripheral neuropathy.

How does TETRAFOL PLUS TABLET work?

TETRAFOL PLUS TABLET works by providing the body with active and readily available forms of essential B vitamins: L-Methylfolate (active Vitamin B9), Methylcobalamin (active Vitamin B12), and Pyridoxal-5-Phosphate (active Vitamin B6). L-Methylfolate is crucial for cell growth, DNA synthesis, and red blood cell formation, especially beneficial for individuals who may have difficulty converting folic acid into its active form. Methylcobalamin is vital for nerve function, brain health, and red blood cell production, helping to maintain the myelin sheath around nerve fibers. Pyridoxal-5-Phosphate supports amino acid metabolism, red blood cell formation, neurotransmitter synthesis, and the regulation of homocysteine levels. Together, these ingredients synergistically support nerve function, red blood cell formation, and overall cellular and metabolic health.

What is the usual dosage of TETRAFOL PLUS TABLET?

The typical dosage for TETRAFOL PLUS TABLET is usually one tablet daily. However, the exact dosage can vary depending on your specific health condition and needs, as determined by your doctor. It is crucial to strictly follow the dosage prescribed by your doctor and not to exceed the recommended dose. For optimal absorption, it is often advised to take the tablet with a full glass of water, preferably on an empty stomach or as directed by your physician. Taking it at the same time each day can help maintain consistent levels in your system and improve adherence.

What are the possible side effects of TETRAFOL PLUS TABLET?

While generally well-tolerated, TETRAFOL PLUS TABLET can cause some side effects, especially if you are allergic to its ingredients. Common side effects include allergic reactions, acne, skin reactions (like itching, redness, rashes, or light sensitivity), nausea, vomiting, abdominal pain, loss of appetite, mild diarrhea, tingling or pricking sensations, sleepiness, and headaches. If you experience any unusual symptoms, adverse reactions, or if side effects worsen, it is recommended to discontinue use and consult your healthcare provider.

Is TETRAFOL PLUS TABLET safe during pregnancy or breastfeeding?

TETRAFOL PLUS TABLET should be used with caution in pregnant and breastfeeding women, and consultation with a doctor is essential. However, it is generally considered safe during pregnancy and is beneficial as folate is essential for the proper development of the fetal neural tube, reducing the risk of neural tube defects like spina bifida. There is no information available about the distribution of TETRAFOL PLUS TABLET in breast milk, but it is considered safe for use while breastfeeding, though consulting a doctor is still advised.

Can TETRAFOL PLUS TABLET be taken with other medications?

TETRAFOL PLUS TABLET can interact with certain medications. It is important to inform your doctor about all medicines you are currently taking, including prescription, over-the-counter drugs, and herbal supplements, to avoid potential interactions. Specific medications that may interact include anticonvulsants (e.g., phenytoin, carbamazepine), some antibiotics (e.g., pyrimethamine, pentamidine, chloramphenicol, erythromycin, cefixime, trimethoprim), levodopa, cholestyramine, colestipol, colchicine, metformin, methotrexate, sulfasalazine, pancreatic enzymes, triamterene, nitrous oxide, and warfarin. Folates might reduce the effectiveness of some anticonvulsants and methotrexate.

What precautions should be taken while taking TETRAFOL PLUS TABLET?

Before taking TETRAFOL PLUS TABLET, inform your doctor about any existing medical conditions you have, such as diabetes, hypertension, kidney or liver problems, or any allergies. Also, disclose all medications you are currently taking, including supplements, and any planned surgeries, as you may be asked to stop taking the supplement at least 2-3 weeks before the procedure. It is advisable to avoid smoking and limit alcohol consumption during treatment. Do not drive or operate machinery if you experience disturbed mental alertness or motor coordination after taking this medicine.

What happens if a dose of TETRAFOL PLUS TABLET is missed?

If you miss a dose of TETRAFOL PLUS TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up or make up for a forgotten dose. If you frequently miss doses, consider setting a reminder or discussing it with your doctor.

How should TETRAFOL PLUS TABLET be stored?

TETRAFOL PLUS TABLET should be stored in a cool, dry place, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. The ideal storage temperature is generally around 20-25°C (room temperature). Ensure the label is read carefully before use.