Sgltd S 5/50mg Tab

SGLTD S 5/50MG Tablet is a combination medication manufactured by Mankind Pharma Ltd., primarily used for the management of type 2 diabetes mellitus in adults. It helps to control elevated blood sugar levels when diet and exercise alone are insufficient.

Name

• Brand Name: SGLTD S 5/50MG Tablet
• Common Name: Dapagliflozin and Sitagliptin Tablets

Composition

Each tablet contains two active ingredients:

• Dapagliflozin: 5 mg (a sodium-glucose cotransporter 2 (SGLT2) inhibitor)
• Sitagliptin: 50 mg (a dipeptidyl peptidase-4 (DPP4) inhibitor)

Uses

SGLTD S 5/50MG Tablet is prescribed for:

• Managing type 2 diabetes mellitus in adults.
• Improving blood sugar control when used with a comprehensive treatment plan including diet and exercise.
• Enhancing insulin action and reducing glucose production by the liver.
• Lowering the risk of cardiovascular disease in patients with type 2 diabetes and existing cardiovascular disease.
• Slowing the progression of kidney disease in some patients.

Dosage and Administration

• Typically taken orally once daily, preferably in the morning.
• Can be taken with or without food.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• The dosage is determined by a healthcare professional based on individual needs and response to treatment.
• Do not stop taking this medicine without consulting your doctor.

Side Effects

Common side effects may include:

• Low blood sugar (hypoglycemia), especially when used with other antidiabetic medicines.
• Headache.
• Upper respiratory tract infection (cold-like symptoms, stuffy or runny nose, sore throat).
• Urinary tract infection and genital fungal infections.
• Diarrhea, nausea, and vomiting.
• Arm or leg pain, joint pain (osteoarthritis).
• Increased frequency of urination.
• Dizziness.

Precautions

• Not recommended during pregnancy or breastfeeding.
• Caution advised with alcohol consumption, as it may increase the risk of low blood sugar and other side effects.
• Inform your doctor if you have kidney or liver problems, heart disease, or a history of allergies to dapagliflozin or sitagliptin.
• Not for use in patients with type 1 diabetes mellitus or diabetic ketoacidosis.
• Regular monitoring of blood sugar levels, kidney function, and liver function is recommended.
• Interactions may occur with insulin, other anti-diabetic medications, diuretics, and NSAIDs.

Storage

• Store in a cool, dry place.
• Keep away from heat, light, and moisture.
• Keep out of the sight and reach of children and pets.

What is SGLTD S 5/50MG TAB used for?

SGLTD S 5/50MG TAB is a combination medicine primarily used to treat Type 2 Diabetes Mellitus in adults. It helps to lower elevated blood sugar levels, especially when diet, exercise, and other medications alone are not sufficient. This medication also plays a vital role in preventing serious complications associated with diabetes, such as eyesight loss (retinopathy), kidney damage (nephropathy), nerve damage (neuropathy), diabetic foot ulcers, and delayed wound healing. Additionally, it may be used to treat chronic kidney disease in adults with reduced kidney function.

How does SGLTD S 5/50MG TAB work?

SGLTD S 5/50MG TAB contains two active ingredients: Dapagliflozin and Sitagliptin. Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that works by increasing the removal of sugar from the body through the kidneys, leading to increased glucose excretion in the urine and thus lowering blood glucose levels. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by increasing the levels of natural substances called incretins. Incretins help regulate blood sugar by stimulating insulin release, particularly after meals, and by decreasing the amount of sugar the liver produces.

What is the usual dosage of SGLTD S 5/50MG TAB?

The recommended starting dose for adults is Dapagliflozin 5 mg + Sitagliptin 50 mg, taken orally once daily. For individuals requiring additional blood sugar control, the dose may be increased to Dapagliflozin 10 mg + Sitagliptin 100 mg once daily, as directed by a healthcare professional. It can be taken with or without food, preferably at the same time each day.

What are the possible side effects of SGLTD S 5/50MG TAB?

Common side effects may include stomach upset, low blood sugar levels (hypoglycemia), nausea, vomiting, diarrhea, headache, constipation, dizziness, runny nose, sore throat, genital infections (such as yeast infections), and urinary tract infections (UTIs). Serious but rare side effects can include diabetic ketoacidosis (DKA) and inflammation of the pancreas (pancreatitis). If you experience any severe or persistent side effects, contact your doctor.

Is SGLTD S 5/50MG TAB safe during pregnancy or breastfeeding?

SGLTD S 5/50MG TAB is generally not recommended during pregnancy or breastfeeding due to limited data on its safety and potential effects on the baby. It is crucial to consult your doctor if you are pregnant, planning pregnancy, or breastfeeding, as they may recommend alternative treatments.

Can SGLTD S 5/50MG TAB be taken with other medications?

This medicine may interact with other medications. It can potentially interact with other anti-diabetic medications (such as insulin or sulfonylureas), diuretics (water pills), hormone medications (like levothyroxine), and corticosteroids. Taking it with insulin or sulfonylureas may increase the risk of low blood sugar. It's important to inform your doctor about all prescription, over-the-counter, and herbal products you are currently taking to avoid potential interactions. Alcohol consumption should be avoided while on this medication as it may cause serious side effects and increase the risk of low blood sugar.

What precautions should be taken while taking SGLTD S 5/50MG TAB?

SGLTD S 5/50MG TAB is not suitable for individuals with Type 1 diabetes mellitus or severe kidney or liver disease. Regular monitoring of blood glucose levels, kidney function, and volume status is recommended. You should be aware of the signs of diabetic ketoacidosis (DKA), acute pancreatitis, hypersensitivity reactions, and urinary tract infections. It's essential not to stop taking this medication abruptly without consulting your doctor, as this can lead to an increase in blood sugar levels and an elevated risk of complications. Always inform your doctor about any pre-existing medical conditions or allergies before starting treatment.

What happens if a dose of SGLTD S 5/50MG TAB is missed?

If you miss a dose of SGLTD S 5/50MG TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose (e.g., less than 12 hours until the next dose), skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should SGLTD S 5/50MG TAB be stored?

Store SGLTD S 5/50MG TAB in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children.