Gabapin Sr 450 Mg Tablet (10 Tab)

Gabapin SR 450 MG Tablet

Gabapin SR 450 MG Tablet, manufactured by Intas Pharmaceuticals Ltd., is an anticonvulsant medication primarily used to manage neuropathic pain and epilepsy.

Composition

The active ingredient in Gabapin SR 450 MG Tablet is Gabapentin, with a strength of 450 mg.

Uses

Gabapin SR 450 MG Tablet is prescribed for:

• Neuropathic Pain: Relief from nerve damage-related pain due to conditions like diabetes, shingles (postherpetic neuralgia), and spinal cord injury. It works by interfering with pain signals traveling through damaged nerves and the brain.
• Epilepsy/Seizures: Used as an adjunctive treatment for partial-onset seizures in adults and children aged 3 years and older. It helps slow down nerve impulses in the brain that cause seizures.
• Other uses: It may also be used to treat fibromyalgia, restless legs syndrome, and occasionally anxiety disorders and hot flashes.

Dosage and Administration

Gabapin SR 450 MG Tablet can be taken with or without food. It is crucial to take this medicine at the same time each day for optimal benefit. Dosage and duration are determined by the doctor based on the patient's condition and response, often starting at a low dose and gradually increasing. Do not stop taking it suddenly, as this may worsen the condition or cause withdrawal symptoms. The tablet should be swallowed whole and not crushed, chewed, broken, or opened.

Side Effects

Common side effects may include:

• Dizziness, sleepiness, drowsiness, and fatigue.
• Nausea, vomiting, diarrhea, constipation.
• Impaired coordination (ataxia), visual disturbance (blurred or double vision), vertigo.
• Fever, viral infection, respiratory tract infection, urinary tract infection.

Serious side effects, though less common, can include:

• Yellowing of the skin or eyes (jaundice).
• Severe allergic reactions (trouble breathing or talking, tightness in chest/throat).
• Unusual mood changes like anxiety, agitation, depression, or suicidal thoughts.
• Unexplained muscle pain or weakness, fever, unusual bruising or bleeding.

Precautions

• Alcohol: Avoid consuming alcohol as it can increase drowsiness and dizziness.
• Pregnancy and Breastfeeding: Consult a doctor before use, as it may be unsafe during pregnancy and is generally not recommended during breastfeeding.
• Kidney Impairment: Use with caution in patients with kidney disease; dosage adjustments may be necessary.
• Driving/Operating Machinery: Avoid these activities if the medicine causes dizziness, drowsiness, or affects vision.
• Suicidal Thoughts: Patients should be monitored for any unusual mood changes or suicidal thoughts, especially at the beginning of treatment.
• Not recommended for children below 6 years of age unless prescribed by a doctor.

Storage

Store Gabapin SR 450 MG Tablet in a cool and dry place, below 30°C, away from direct sunlight and moisture. Keep out of sight and reach of children.

Here are some frequently asked questions about GABAPIN SR 450 MG TABLET:

What is GABAPIN SR 450 MG TABLET used for?

GABAPIN SR 450 MG TABLET is primarily used to treat nerve pain (neuropathic pain) caused by conditions such as diabetic neuropathy, shingles (postherpetic neuralgia), and spinal cord injury. It is also prescribed to help manage epilepsy (seizures) as an add-on therapy for partial seizures in adults and children aged 3 years and older. Additionally, it can be used for fibromyalgia (body-wide pain and fatigue) and restless legs syndrome.

How does GABAPIN SR 450 MG TABLET work?

GABAPIN SR 450 MG TABLET contains Gabapentin, which is an anticonvulsant that works by calming overactive nerves in the body. It achieves this by binding to a specific site on voltage-gated calcium channels (alpha-2-delta subunit) in nerve cells, which helps to reduce the release of excitatory neurotransmitters that contribute to pain signals and seizures. This action interferes with pain signals traveling through damaged nerves and the brain, and it helps lower the risk of seizures.

What is the usual dosage for GABAPIN SR 450 MG TABLET?

The exact dose and duration of treatment for GABAPIN SR 450 MG TABLET will be determined by your doctor, based on your condition and how you respond to the medication. Treatment typically begins with a low dose and is increased gradually. It can be taken with or without food, but it is important to take it at the same time each day to get the most benefit. The tablet should be swallowed whole and not crushed, chewed, or broken.

What are the possible side effects of GABAPIN SR 450 MG TABLET?

Common side effects of GABAPIN SR 450 MG TABLET include dizziness, sleepiness (somnolence), fatigue, nausea, vomiting, swelling (peripheral edema), and impaired balance or coordination (ataxia). Most of these side effects are usually mild and may go away as your body adjusts to the medicine. Serious side effects, though less common, can include suicidal thoughts or behaviors, severe allergic reactions (such as skin rash, difficulty breathing, swelling of face/throat, or yellowing of skin/eyes), and signs of infection like fever or unusual bleeding. If you experience persistent or severe side effects, or any unusual mood changes, you should consult your doctor immediately.

Is GABAPIN SR 450 MG TABLET safe during pregnancy or breastfeeding?

GABAPIN SR 450 MG TABLET is generally not recommended during pregnancy unless your doctor determines that the benefits outweigh the potential risks, as there is limited information on its safety for the unborn baby. Animal studies have shown harmful effects on developing babies. If you are pregnant, planning a pregnancy, or become pregnant while taking this medicine, consult your doctor urgently. For breastfeeding mothers, Gabapentin is considered probably safe if prescribed, but the baby should be monitored for excessive sleepiness, adequate weight gain, and developmental milestones.

Can GABAPIN SR 450 MG TABLET be taken with other medications?

GABAPIN SR 450 MG TABLET can interact with certain medications. For example, antacids containing aluminum and magnesium should be taken at least two hours after taking Gabapentin SR 450 MG TABLET, as they can reduce its absorption. Taking it with opioid pain medications like morphine, fentanyl, or hydrocodone may increase drowsiness, sleepiness, and the risk of breathing difficulties. Concurrent use with alcohol or St. John's Wort (an herbal supplement for depression) is not recommended as it can worsen side effects like dizziness and sleepiness. Always inform your doctor about all the medicines, supplements, or herbal products you are currently taking or plan to take to avoid potential interactions.

What precautions should be taken while using GABAPIN SR 450 MG TABLET?

Avoid consuming alcohol while taking this medicine as it can increase dizziness and sleepiness. Due to potential side effects like dizziness, drowsiness, or blurred vision, you should not drive or operate heavy machinery until you know how the medication affects you. Do not stop taking GABAPIN SR 450 MG TABLET abruptly without consulting your doctor, as this can lead to withdrawal symptoms or worsen your condition, especially for epilepsy patients where it may increase seizure frequency. Inform your doctor if you have kidney problems, liver impairment, heart problems, or a history of drug addiction or suicidal thoughts.

What happens if a dose of GABAPIN SR 450 MG TABLET is missed?

If you miss a dose of GABAPIN SR 450 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should GABAPIN SR 450 MG TABLET be stored?

GABAPIN SR 450 MG TABLET should be stored in a cool and dry place, away from direct sunlight. Keep it in its original packaging to protect it from moisture. Ensure it is kept out of sight and reach of children.