Cilniblu T Tablet

CILNIBLU T TABLET by BLUE CROSS LABORATORIES LTD is a combination medication used to manage hypertension (high blood pressure) and reduce the risk of associated cardiovascular events.

Name

• Brand Name: CILNIBLU T TABLET
• Manufacturer: Blue Cross Laboratories Ltd.

Composition

Each film-coated tablet contains two active ingredients:

• Cilnidipine IP (10 mg): A calcium channel blocker that works by relaxing and widening blood vessels, allowing blood to flow more easily and reducing the heart's workload. It has a unique action on both L-type and N-type calcium channels.
• Telmisartan IP (40 mg): An angiotensin II receptor blocker (ARB) that blocks the action of angiotensin II, a hormone responsible for constricting blood vessels. This action helps to relax blood vessels and lower blood pressure, providing sustained control throughout the day due to its long duration of action.

Uses

CILNIBLU T TABLET is primarily prescribed for:

• Treatment of Hypertension (High Blood Pressure).
• Reduction in the risk of cardiovascular events such as heart attack and stroke.
• Prevention of Angina (heart-related chest pain).
• Kidney protection, especially in patients with hypertension and diabetes.

Dosage and Administration

• CILNIBLU T TABLET is typically prescribed for once-daily administration.
• The tablet should be swallowed whole with a glass of water, without crushing or chewing it.
• It can be taken with or without food; however, it is recommended to take it at the same time each day to maintain consistent drug levels.
• The dosage and duration of treatment are determined by the healthcare provider based on the individual patient's condition, severity of hypertension, and response to treatment.
• Do not stop taking the medication abruptly without consulting your doctor, as sudden cessation can lead to severe heart-related conditions, including a sudden rise in blood pressure.
• If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.

Side Effects

Common Side Effects:

• Headache
• Dizziness
• Flushing (sense of warmth in the face, ears, neck, and trunk)
• Ankle swelling (edema)
• Fatigue or tiredness
• Palpitations (uneven heartbeat)
• Indigestion or upset stomach, nausea
• Sinusitis, pharyngitis, back pain
• Changes in taste

Serious Side Effects (less common):

• Low blood pressure (hypotension)
• Increased heart rate
• Muscle cramps
• Allergic reactions (rash, itching, swelling, especially of the face, tongue, or throat - angioedema, anaphylactic reaction)
• Increased potassium levels in the blood (hyperkalaemia)
• Cardiogenic shock (rare)
• Acute renal failure Consult your doctor immediately if any severe or persistent side effects occur.

Precautions

• Contraindications:
  • Allergy to Cilnidipine, Telmisartan, or any other components of the tablet.
  • Pregnancy: Contraindicated due to definite evidence of risk to the developing baby.
  • Breastfeeding: Not recommended.
  • Severe liver impairment, hepatic coma or pre-coma, or biliary obstructive disorder.
  • Severe aortic stenosis, cardiogenic shock, recent myocardial infarction (MI) or acute unstable angina, heart failure, and existing low blood pressure (hypotension).
  • Children under 18 years of age.
  • Diabetic patients taking aliskiren.
• General Warnings:
  • Use with caution in patients with congestive heart failure, liver disease, kidney problems (renal impairment), and peripheral edema.
  • Regular monitoring of blood pressure and kidney function is recommended during treatment.
  • Alcohol: Avoid or limit alcohol consumption as it can enhance the blood pressure-lowering effect and increase the risk of dizziness and low blood pressure.
  • Driving and Operating Machinery: Avoid these activities if you experience dizziness after taking the medication.
  • Inform your doctor about all pre-existing medical conditions, allergies, and all other medications (including over-the-counter drugs, supplements, and herbal remedies) you are currently taking to avoid potential drug interactions.
  • Older patients (above 65 years) should use this medication with caution, and dose adjustment may be required under medical supervision.
  • Potential drug interactions include diuretics (e.g., furosemide, hydrochlorothiazide), lithium-based medicines, ACE inhibitors, other ARBs, aliskiren, anti-psychotic drugs (e.g., risperidone, quetiapine), digoxin, quinidine, antidepressants (e.g., paroxetine, fluoxetine), NSAIDs, and corticosteroids.

Storage

• Store CILNIBLU T TABLET at room temperature, not exceeding 30°C.
• Keep the medicine protected from light and moisture.
• Ensure it is kept in a secure location, out of sight and reach of children.

CILNIBLU T TABLET is a medication used to treat hypertension (high blood pressure). It contains two active ingredients: Cilnidipine and Telmisartan.

Here are some frequently asked questions about CILNIBLU T TABLET:

What is CILNIBLU T TABLET used for?

CILNIBLU T TABLET is primarily used to treat essential hypertension (high blood pressure) in adults. It helps to manage and control high blood pressure levels, which in turn reduces the risk of associated health problems such as heart attacks, strokes, and kidney issues. It may also be used for the prevention of angina (heart-related chest pain).

How does CILNIBLU T TABLET work?

CILNIBLU T TABLET contains two active ingredients: Cilnidipine and Telmisartan.

• Cilnidipine is a calcium channel blocker (CCB). It works by relaxing and widening blood vessels, specifically blocking L-type and N-type calcium channels. This reduces the workload on the heart and lowers blood pressure.
• Telmisartan is an angiotensin receptor blocker (ARB). It blocks the action of angiotensin II, a hormone that causes blood vessels to narrow. By preventing this action, Telmisartan allows blood vessels to relax and widen, making it easier for the heart to pump blood throughout the body. The combined action of these two medications provides a dual approach to effectively lower blood pressure.

What is the usual dosage of CILNIBLU T TABLET?

The recommended dosage of CILNIBLU T TABLET varies based on the individual's condition, severity of hypertension, and response to treatment. It is crucial to follow your physician's instructions strictly. Typically, it is taken once daily, usually at the same time each day, with or without food. Do not crush or chew the tablet. Your doctor may adjust the dose based on your blood pressure readings and tolerance, usually at intervals of 2-4 weeks.

What are the possible side effects of CILNIBLU T TABLET?

Common side effects may include:

• Ankle swelling (edema)
• Headache
• Dizziness
• Flushing (a warm sensation in the face, ears, neck, and trunk)
• Tiredness/Fatigue
• Palpitations (uneven heartbeat)
• Upset stomach/Indigestion/Nausea
• Increased potassium levels in the blood (hyperkalemia)
• Changes in taste In rare cases, more serious side effects like cardiogenic shock may occur. If any side effects persist or worsen, consult your doctor.

Is CILNIBLU T TABLET safe during pregnancy or breastfeeding?

CILNIBLU T TABLET is generally not recommended for use during pregnancy as it may harm the unborn baby. If you become pregnant while taking this medication, stop use and contact your doctor immediately. Information regarding its use during breastfeeding is not readily available, so breastfeeding mothers should consult their doctor to assess potential risks.

Can CILNIBLU T TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications, supplements, and herbal products you are currently taking to avoid potential drug interactions. CILNIBLU T TABLET may interact with:

• Diuretics (e.g., furosemide, hydrochlorothiazide): May increase the risk of low blood pressure and electrolyte imbalance.
• NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) like ibuprofen or naproxen: Can reduce the blood pressure-lowering effects of CILNIBLU T TABLET and increase the risk of kidney problems.
• Lithium-based medicines: May increase serum lithium levels, leading to potential toxicity.
• Digoxin: May increase serum digoxin levels.
• Potassium supplements or potassium-sparing diuretics: May heighten the risk of high potassium levels in the blood.
• Angiotensin-converting enzyme (ACE) inhibitors or other angiotensin-II receptor antagonists: May interact, affecting blood pressure management.
• Antipsychotic drugs (e.g., risperidone, quetiapine) or antidepressants (e.g., paroxetine, fluoxetine): May interact.

What precautions should be taken?

• Kidney and Liver Issues: Inform your doctor if you have any kidney or liver complications, as regular monitoring of kidney function may be necessary.
• Dehydration: Inform your physician if you have severe dehydration.
• Driving and Operating Machinery: This medication may cause dizziness or sleepiness. Avoid driving or performing tasks that require focus until you know how it affects you.
• Alcohol Consumption: It is advisable to avoid or limit alcohol consumption as it can enhance the blood pressure-lowering effect and increase the risk of dizziness.
• Stopping the Medication: Do not stop taking CILNIBLU T TABLET suddenly without consulting your doctor, as abrupt cessation can lead to a sudden increase in blood pressure or other serious heart-related issues.
• Heart Conditions: Use with caution in patients with congestive heart failure, cardiogenic shock, recent myocardial infarction, or acute unstable angina.
• Monitoring: Regular monitoring of blood pressure and kidney function tests may be necessary during treatment.

What happens if a dose is missed?

If you forget to take a dose of CILNIBLU T TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your usual dosing schedule. Do not take a double dose to make up for the missed one.

How should CILNIBLU T TABLET be stored?

Store CILNIBLU T TABLET at room temperature, not exceeding 30°C. Keep the medicine protected from light and moisture, and in a secure location out of reach of children. Always check the expiry date on the packaging before use.