Bizlo-od 30

Here is a detailed product description for BIZLO-OD 30:

BIZLO-OD 30

Name

• Common Name: Baclofen
• Brand Name: BIZLO-OD 30, BIZLO OD 30mg Tablet SR

Composition

BIZLO-OD 30 contains Baclofen as its active ingredient, in a strength of 30mg. It is a sustained-release (SR) tablet.

Uses

BIZLO-OD 30 is a muscle relaxant used to manage muscle spasms (painful muscle contractions), rigidity, tension, and stiffness (spasticity). It is prescribed for conditions such as:

• Cerebral palsy
• Multiple sclerosis
• Stroke (cerebrovascular accidents)
• Spinal cord disorders or injuries
• Motor neuron disease
• Other nerve or brain-related disorders affecting the nervous system

It works by acting on the brain and spinal cord to relieve muscle stiffness or spasm, thereby improving muscle movement.

Dosage and Administration

BIZLO-OD 30 should be taken exactly as advised by your physician. It is an oral tablet that should be swallowed whole, not crushed or chewed. It is preferably taken with food or milk to minimize nausea. The doctor will determine the correct dose and duration based on age, body weight, and disease condition.

Treatment should generally start with a low dose and gradually increase until optimal response is achieved, especially in the elderly. Do not stop taking BIZLO-OD 30 suddenly, as it can lead to severe withdrawal symptoms. Discontinuation should always be gradual, typically by successively reducing the dosage over 1 to 2 weeks. BIZLO-OD 30 tablets are not suitable for use in children below 33 kg body weight or under 16 years due to limited data.

Side Effects

Common side effects of BIZLO-OD 30 include:

• Nausea, vomiting, diarrhea, constipation, dry mouth
• Tiredness, sleepiness, drowsiness, fatigue
• Weak limbs, muscle pain, weakness
• Dizziness, unsteadiness or shaky feeling
• Headache
• Lack of sleep, nightmares
• Confusion
• Sedation
• Blurred vision
• Excessive sweating

More serious or less common side effects can include:

• Hallucinations
• Breathing difficulties
• Vision problems
• Increased liver enzymes
• Feeling faint due to low blood pressure (hypotension)
• Convulsions (fits) or seizures
• Hypotonia (decreased muscle tone)
• Agitation
• Urinary retention
• Mood changes, mental disorders, feeling attacked or persecuted
• Suicidal thoughts (inform your doctor immediately if experienced)

Sudden discontinuation can lead to withdrawal symptoms such as muscle spasms, increased muscle tightness, fast heart rate, fever, confusion, hallucinations, mood changes, mental disorders, or convulsions.

Precautions

• Medical Conditions: Inform your doctor about any pre-existing conditions such as stomach ulcers, kidney, liver, or heart problems, diabetes, hypertension, epilepsy (fits/seizures), any mental illness, Parkinson's disease, or a history of alcoholism or drug abuse.
• Alcohol Consumption: Avoid alcohol as it can increase drowsiness and sedative effects.
• Activities Requiring Alertness: BIZLO-OD 30 may cause excessive sleepiness, dizziness, or affect vision, impairing alertness. Do not drive or operate heavy machinery until you know how the medicine affects you.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding. It may be unsafe during pregnancy, but generally safe during breastfeeding if prescribed.
• Kidney and Liver Impairment: Use with caution in patients with kidney or liver disease. Dose adjustments may be necessary, and severe kidney dysfunction can lead to accumulation in the brain.
• Diabetes: BIZLO-OD 30 may alter blood sugar levels; close monitoring is advised for diabetic patients.
• Overdose: In case of accidental overdose, seek immediate medical attention. Symptoms may include increased drowsiness, breathing difficulties, confusion, hallucinations, seizures, low blood pressure, slow heartbeat, muscle weakness, nausea, or vomiting.

Storage

Store BIZLO-OD 30 at room temperature, preferably below 30°C, in a cool and dry place. Keep it protected from heat, direct sunlight, and moisture. Ensure it is kept out of the sight and reach of children and pets. Do not use expired medicine.

BIZLO-OD 30 by TORRENT PHARMACEUTICALS LTD is a muscle relaxant primarily used to alleviate muscle spasms, stiffness, and tension associated with various neurological conditions.

1. What is BIZLO-OD 30 used for?

BIZLO-OD 30 is used to manage muscle spasms (painful muscle contractions), rigidity, and stiffness that occur due to conditions affecting the nervous system. These conditions include cerebral palsy, multiple sclerosis, stroke, spinal cord injuries, and other nerve or spinal cord disorders.

2. How does BIZLO-OD 30 work?

BIZLO-OD 30 contains Baclofen, which is a muscle relaxant. It works by increasing the effects of certain chemical messengers, such as GABA (gamma-aminobutyric acid), in the spinal cord. This action helps to induce muscle relaxation, relieve pain from muscle spasms, and improve muscle movement.

3. What is the usual dosage of BIZLO-OD 30?

The dosage of BIZLO-OD 30 is determined by a physician and is adjusted to individual patient requirements. Treatment typically starts with a low dose, such as 15 mg daily, preferably in divided doses, and is gradually increased. Satisfactory control of symptoms is often achieved with doses up to 60 mg daily, but the maximum daily dose for adults should not exceed 100 mg. For patients with impaired renal function, a particularly low dosage of approximately 5 mg daily may be selected.

4. What are the possible side effects of BIZLO-OD 30?

Common side effects include drowsiness, confusion, weakness, dizziness, nausea, headache, dry mouth, tiredness, and feeling unsteady or shaky. Other possible side effects can include constipation, diarrhea, sleepiness, muscle pain, and vision problems.

5. Is BIZLO-OD 30 safe during pregnancy or breastfeeding?

BIZLO-OD 30 is generally not recommended for use in pregnant women unless considered absolutely necessary by a physician, as the unborn baby may be exposed and develop withdrawal symptoms after birth. It should be used with caution in breastfeeding women, and a doctor will weigh the benefits and risks, monitoring the baby for symptoms like sedation.

6. Can BIZLO-OD 30 be taken with other medications?

BIZLO-OD 30 can interact with several medications. Inform your doctor if you are taking other muscle relaxants (e.g., tizanidine), antidepressants (e.g., lithium, amitriptyline), antihypertensives (e.g., diltiazem), pain killers (e.g., ibuprofen, morphine), anti-Parkinsonian agents (e.g., levodopa or carbidopa), antiallergic medicines (e.g., promethazine), sedatives (e.g., temazepam), or antiepileptics (e.g., carbamazepine), as increased sedation or other adverse effects may occur.

7. What precautions should be taken while using BIZLO-OD 30?

Patients should inform their doctor about pre-existing conditions such as stomach ulcers, kidney, liver, heart, lung problems, diabetes, fits, mental illness, or a history of alcoholism. Avoid alcohol consumption as it can increase drowsiness. Driving or operating heavy machinery should be avoided until you know how the medicine affects you, due to potential dizziness and sleepiness. Abruptly stopping BIZLO-OD 30 can cause severe withdrawal symptoms, so discontinuation should always be gradual under medical supervision.

8. What happens if a dose of BIZLO-OD 30 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

9. How should BIZLO-OD 30 be stored?

BIZLO-OD 30 should be stored in a cool and dry place, away from heat and direct light. It should be kept out of the reach of children and pets.

10. Can BIZLO-OD 30 affect kidney or liver function?

Yes, BIZLO-OD 30 should be used with caution in patients with kidney or liver problems. It may affect liver function by elevating certain liver enzymes. For kidney issues, a lower dose might be prescribed, and patients should be monitored for side effects like changes in urination patterns.