Cresar H Tablet (15 Tab)

CRESAR H TABLET, manufactured by Cipla Ltd., is a combination medication primarily prescribed for the management of hypertension (high blood pressure).

Name

• Brand Name: CRESAR H TABLET
• Common Name: Telmisartan and Hydrochlorothiazide Tablets

Composition

Each uncoated tablet typically contains:

• Telmisartan IP: 40 mg
• Hydrochlorothiazide IP: 12.5 mg

Uses

CRESAR H TABLET is indicated for:

• Treatment of hypertension (high blood pressure), especially as a second-line therapy when blood pressure is not adequately controlled by telmisartan alone.
• Reducing the risk of cardiovascular events such as stroke and heart attack.
• Managing edema or fluid retention in certain conditions like heart failure, liver cirrhosis, and nephrotic syndrome.

Dosage and Administration

CRESAR H TABLET is for once-daily oral administration and can be taken with or without food. Tablets should be swallowed whole with water. This fixed-dose combination is not indicated for initial therapy for hypertension.

Side Effects

Common side effects may include:

• Dizziness, headache, fatigue, weakness
• Nausea, diarrhea, stomach pain
• Increased urination
• Back pain, muscle pain

Serious side effects, though rare, can include:

• Angioedema
• Electrolyte imbalances (e.g., hyperkalemia, changes in potassium levels)
• Severe dehydration
• Kidney problems, including renal insufficiency
• Decreased vision or eye pain

Precautions

• Pregnancy: Not recommended during the first trimester and contraindicated during the second and third trimesters due to potential harm to the fetus.
• Breastfeeding: Not recommended.
• Kidney/Liver Disease: Use with caution in patients with mild to moderate renal impairment; contraindicated in severe renal impairment (creatinine clearance <30 mL/min) and severe hepatic impairment.
• Diabetes: May impair glucose tolerance; blood glucose monitoring is advised.
• Alcohol: Avoid concomitant use as it may increase the risk of dizziness and liver damage.
• Drug Interactions: Caution with potassium-sparing diuretics, potassium supplements, NSAIDs, cardiac glycosides, anticoagulants, and aliskiren.

Storage

Store CRESAR H TABLET protected from light and moisture at a temperature not exceeding 30 °C. Keep in a cool, dry place, away from direct sunlight, moisture, heat, and out of the reach of children and pets.

What is Cresar H Tablet used for?

Cresar H Tablet is primarily used to treat hypertension (high blood pressure). By lowering blood pressure, it helps reduce the risk of serious cardiovascular events such as heart attack, stroke, and kidney problems. It can also help manage edema (fluid retention) that may occur due to conditions like heart failure or liver cirrhosis.

How does Cresar H Tablet work?

Cresar H Tablet combines two active ingredients: Telmisartan and Hydrochlorothiazide. Telmisartan is an angiotensin II receptor blocker (ARB) that works by relaxing and widening blood vessels, allowing blood to flow more easily and reducing the workload on the heart. Hydrochlorothiazide is a thiazide diuretic (water pill) that increases the excretion of excess salt and water from the body through urine, which also contributes to lowering blood pressure.

What is the usual dosage for Cresar H Tablet?

The typical adult dosage is one tablet once a day. The specific dose (e.g., 40 mg Telmisartan and 12.5 mg Hydrochlorothiazide) depends on your doctor's assessment of your blood pressure control and may be adjusted every 2 to 4 weeks if needed. It can be taken with or without food. It's important to follow your doctor's instructions exactly.

What are the possible side effects of Cresar H Tablet?

Common side effects can include dizziness, headache, fatigue, nausea, diarrhea, and cold/flu symptoms. Some people may also experience back pain or high levels of uric acid in their blood. More serious but less common side effects can include light-headedness, vision problems, unexplained muscle pain/weakness, or signs of kidney problems. If you experience severe or persistent side effects, contact your doctor.

Is Cresar H Tablet safe during pregnancy or breastfeeding?

Cresar H Tablet is generally not recommended during pregnancy, especially in the second and third trimesters, as it can harm the unborn baby, potentially causing kidney damage, lung problems, and other complications. If you become pregnant while taking this medicine, stop immediately and contact your doctor.

For breastfeeding, Telmisartan may pass into breast milk, and hydrochlorothiazide is known to be excreted in small amounts. Due to potential risks to the infant, it is generally not recommended. Your doctor will weigh the benefits and risks or may suggest an alternative medication.

Can Cresar H Tablet be taken with other medications?

Cresar H Tablet can interact with various medications. It's crucial to inform your doctor about all other medicines, supplements, and herbal products you are taking. Specific interactions include:

• Lithium and NSAIDs (Non-Steroidal Anti-Inflammatory Drugs): These can reduce the blood pressure-lowering effect and may worsen kidney function.
• Potassium supplements or salt substitutes containing potassium: These should generally be avoided unless advised by your doctor, as the medicine can affect potassium levels.
• Other blood pressure medications, especially ACE inhibitors or aliskiren: Dual blockade of the renin-angiotensin system (RAS) increases risks of low blood pressure, high potassium, and changes in kidney function.
• Bile acid sequestrants (e.g., cholestyramine, colestipol, colesevelam): Take Cresar H Tablet at least 4 hours before or 4-6 hours after these medications.
• Cardiac glycosides (e.g., digoxin) and anticoagulants (e.g., warfarin): Cresar H Tablet may alter their levels or effects.

What precautions should be taken while using Cresar H Tablet?

Regular check-ups with your doctor, including blood and urine tests, are important to monitor your progress and check for unwanted effects like electrolyte imbalances or changes in kidney function. This medicine can cause dizziness or lightheadedness, so be cautious when driving or operating machinery until you know how it affects you. Dehydration from severe vomiting, diarrhea, or excessive sweating can lead to low blood pressure, so ensure adequate fluid intake. Patients with diabetes should monitor their blood sugar levels closely, as hydrochlorothiazide can affect them. Also, avoid unnecessary sun exposure and use sunscreen, as hydrochlorothiazide can increase skin sensitivity to sunlight.

What happens if a dose of Cresar H Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Cresar H Tablet be stored?

Store Cresar H Tablet in its closed container at room temperature, away from heat, moisture, and direct light. Do not freeze the medicine. Keep it out of the reach of children and pets. Properly dispose of any outdated or no longer needed medicine as advised by your healthcare professional.