Sitaglo Gm 1/50/1000mg Tab

SITAGLO GM 1/50/1000MG TAB by ARISTO PHARMA

SITAGLO GM 1/50/1000MG Tablet is a prescription medication used in the management of Type 2 Diabetes Mellitus. It is manufactured by Aristo Pharmaceuticals Pvt Ltd.

• Name

  • Common Name: SITAGLO GM 1/50/1000MG Tablet
  • Brand Name: SITAGLO GM

• Composition Each tablet contains a combination of three active ingredients:

  • Glimepiride: 1mg
  • Sitagliptin: 50mg
  • Metformin: 1000mg

• Uses SITAGLO GM 1/50/1000MG Tablet is prescribed for the treatment of Type 2 Diabetes Mellitus in adults. It is typically used when diet, exercise, and other treatments alone are insufficient to achieve adequate glycemic control. The medicine helps to lower blood glucose levels, improve the body's response to insulin, and reduce the risk of long-term diabetes complications such as kidney damage, eye damage, nerve problems, and cardiovascular diseases like heart attack or stroke.

• Dosage and Administration This medication should be taken regularly as directed by a healthcare professional.

  • Typical Guidance: Usually taken once or twice daily with meals.
  • With Food: It is recommended to take the tablet with food to reduce the chance of stomach upset and lower the risk of hypoglycemia (low blood sugar).
  • Consistency: Take at the same time each day for maximum benefits.
  • Do Not Stop Abruptly: Do not discontinue the medication without consulting your doctor, as this could lead to a rise in blood sugar levels and associated complications.
  • Swallow Whole: Do not crush, break, or chew the tablet.

• Side Effects

  • Common Side Effects: Nausea, vomiting, stomach upset, diarrhea, constipation, headache, hypoglycemia (low blood sugar), weight gain, metallic taste, flatulence, loss of appetite, and changes in taste.
  • Serious Side Effects: Seek immediate medical attention if you experience severe symptoms such as difficulty breathing, chest pain, signs of lactic acidosis (e.g., muscle pain, weakness, dizziness, rapid breathing), skin blisters, or very low/high blood sugar.

• Precautions

  • Contraindications: Do not take if you have Type 1 diabetes mellitus, acute or chronic metabolic acidosis (including diabetic ketoacidosis), active bladder cancer or a history of bladder cancer, severe kidney or liver disease, or an allergy to any of its components.
  • Alcohol: Avoid consuming alcohol, as it can increase the risk of hypoglycemia and lactic acidosis.
  • Pregnancy and Breastfeeding: Not recommended during pregnancy or while breastfeeding; consult your doctor.
  • Driving: Exercise caution as blood sugar fluctuations can affect your ability to drive.
  • Kidney/Liver Issues: Use with caution in patients with severe kidney disease and is not recommended for severe liver or kidney problems.
  • Hypoglycemia Risk: Always carry sugary food or fruit juice to manage symptoms of low blood sugar.
  • Drug Interactions: Inform your doctor about all other medications, including herbal tonics and supplements, as some can interact with this medicine.
  • Medical Procedures: Inform your doctor if you are scheduled for an X-ray procedure involving a dye, as the medicine may need to be stopped temporarily.

• Storage Store SITAGLO GM 1/50/1000MG Tablet in a cool, dry place at a temperature not exceeding 30°C, away from direct sunlight. Keep it out of the sight and reach of children and pets. Do not use past the expiry date.

SITAGLO GM 1/50/1000MG Tablet by ARISTO PHARMA is a combination medication containing Sitagliptin, Glimepiride, and Metformin, primarily prescribed for the management of Type 2 Diabetes Mellitus. This medication works by addressing various aspects of blood sugar regulation to help achieve better glycemic control in adults when diet, exercise, or single-drug treatments are insufficient.

What is SITAGLO GM 1/50/1000MG used for?

SITAGLO GM 1/50/1000MG is an antidiabetic medicine used to treat Type 2 Diabetes Mellitus in adults. It helps manage elevated blood sugar levels when lifestyle modifications alone or other blood sugar-lowering medicines do not provide sufficient control. It aids in glycemic balance throughout the day, including after meals and during fasting periods, and helps reduce the risk of diabetes-associated complications such as kidney or eye damage.

How does SITAGLO GM 1/50/1000MG work?

This medicine combines three active ingredients, each with a distinct mechanism of action:

• Sitagliptin enhances glucose-mediated insulin secretion by increasing the levels of certain natural substances (incretins) in the body. It also signals the liver to reduce glucose production when blood sugar is high.
• Glimepiride stimulates beta cells in the pancreas to produce more insulin, helping the body utilize glucose effectively and improving insulin sensitivity.
• Metformin reduces sugar production by liver cells, delays sugar absorption from the intestines, and enhances the body's response to insulin.

What is the usual dosage for SITAGLO GM 1/50/1000MG?

SITAGLO GM 1/50/1000MG should be taken once or twice daily with meals, as prescribed by your doctor. Taking it with food can help reduce stomach upset or gastrointestinal side effects. It should be swallowed whole with a glass of water and not crushed, broken, or chewed. Your doctor will determine the appropriate dose and duration based on your condition and response to treatment.

What are the possible side effects of SITAGLO GM 1/50/1000MG?

Common side effects may include vomiting, nausea, abdominal pain, headache, frequent urination, loose stools (diarrhea), metallic taste, flatulence, loss of appetite, constipation, and allergic reactions. More serious side effects can include hypoglycemia (low blood sugar), which can cause symptoms like fatigue, dizziness, cold sweats, tremor, and anxiety. There is also a rare but serious risk of lactic acidosis, particularly with Metformin accumulation, especially in patients with kidney or liver issues. If any side effects persist or worsen, or if you experience severe symptoms like difficulty breathing or chest pain, consult your doctor immediately.

Is SITAGLO GM 1/50/1000MG safe during pregnancy or breastfeeding?

SITAGLO GM 1/50/1000MG is generally not recommended during pregnancy or while breastfeeding. There are inadequate studies on its effects in pregnancy, and components of the tablet can pass into breast milk, potentially harming the baby. If you are pregnant, planning pregnancy, or breastfeeding, you should inform your doctor, who may suggest a different, safer medication.

Can SITAGLO GM 1/50/1000MG be taken with other medications?

SITAGLO GM 1/50/1000MG can interact with other medications, potentially affecting its efficacy or increasing the risk of side effects. For example, when taken with insulin or other sulfonylureas (like glibenclamide), it can increase the risk of low blood sugar (hypoglycemia). Diuretics (e.g., furosemide, hydrochlorothiazide) and corticosteroids (e.g., prednisone) may also interact with SITAGLO GM. It is crucial to inform your doctor about all medicines, vitamins, supplements, and herbal tonics you are taking to prevent unwanted interactions.

What precautions should be taken while using SITAGLO GM 1/50/1000MG?

Several precautions should be observed:

• Allergies: Avoid if allergic to any of its components.
• Kidney/Liver Disease: Not recommended for patients with severe kidney or liver disease due to increased risk of lactic acidosis. Your doctor will assess kidney function.
• Heart Conditions: Use with caution if you have a history of heart disease, such as congestive heart failure.
• Alcohol: Avoid alcohol consumption, as it increases the risk of hypoglycemia and lactic acidosis.
• Surgery/Procedures: Inform your doctor if you are undergoing surgery or X-ray procedures involving injected dyes, as you may need to temporarily stop the medication.
• Other conditions: Not for Type 1 diabetes or diabetic ketoacidosis. Caution is advised for elderly patients and not recommended for children under 18 years of age.
• Hypoglycemia: Always carry sugary food or fruit juice to manage potential low blood sugar episodes.

What happens if a dose of SITAGLO GM 1/50/1000MG is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can cause your blood sugar level to fall rapidly.

How should SITAGLO GM 1/50/1000MG be stored?

Store SITAGLO GM 1/50/1000MG in a cool, dry place, away from direct sunlight. The storage temperature should be between 10°C to 25°C or below 30°C. Keep the medicine out of the sight and reach of children and pets.