Rantac Syrup 75mg/5ml(30ml)

RANTAC SYRUP 75MG/5ML

RANTAC SYRUP is an oral medication manufactured by J B Chemicals and Pharmaceuticals Ltd., commonly known as Ranitidine Syrup.

• Composition: Each 5ml of syrup contains Ranitidine Hydrochloride IP equivalent to 75mg of Ranitidine, in a flavoured syrup base.

• Uses: This medicine is a histamine H2 receptor blocker used to reduce the amount of acid produced in the stomach. It is prescribed for the treatment and prevention of:

  • Heartburn, indigestion, and acid reflux.
  • Gastroesophageal Reflux Disease (GERD) and erosive esophagitis.
  • Active duodenal and benign gastric ulcers.
  • Pathological hypersecretory conditions such as Zollinger-Ellison syndrome and systemic mastocytosis.
  • Prevention of stomach ulcers associated with NSAID use.

• Dosage and Administration: The typical adult oral dosage for conditions like active duodenal ulcer is 150 mg (10 mL of syrup) twice daily, or 300 mg (20 mL of syrup) once daily at bedtime. For erosive esophagitis, the recommended adult dose is 150 mg (10 mL of syrup) four times daily. Pediatric dosing (1 month to 16 years) varies by condition and weight, usually 2 to 4 mg/kg twice daily for ulcers, or 5 to 10 mg/kg/day in two divided doses for GERD/erosive esophagitis. It can be taken with or without food. Shake the bottle well before use and measure the dose accurately.

• Side Effects: Common side effects may include headache, nausea, vomiting, diarrhea, constipation, stomach pain, dizziness, and drowsiness. Serious but rare side effects can include allergic reactions (rash, hives, swelling, breathing difficulties), severe stomach pain (pancreatitis), liver problems, kidney problems, or irregular heartbeat.

• Precautions: RANTAC SYRUP is contraindicated in patients with known hypersensitivity to ranitidine or other H2 receptor blockers. Caution is advised in patients with impaired renal or hepatic function, and those with a history of acute porphyria, as it may precipitate attacks. Consult a doctor before use if pregnant or breastfeeding. Alcohol consumption is not recommended as it can increase stomach acid. Interactions may occur with drugs like warfarin, ketoconazole, atazanavir, glipizide, triazolam, delavirdine, and gefitinib.

• Storage: Store RANTAC SYRUP below 30°C in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.

Rantac Syrup 75mg/5ml, containing ranitidine, is a medication primarily used to reduce stomach acid. Below are frequently asked questions regarding this medicine.

What is Rantac Syrup used for?

Rantac Syrup is used to treat and prevent conditions related to excess stomach acid. This includes acidity, heartburn, indigestion, acid reflux, gastroesophageal reflux disease (GERD), and stomach (peptic) ulcers. It can also be used for conditions like Zollinger-Ellison syndrome (where the stomach produces too much acid), erosive esophagitis (inflammation of the food pipe), and to prevent ulcers caused by certain painkillers.

How does Rantac Syrup work?

Rantac Syrup contains ranitidine, which is a histamine H2-receptor antagonist. It works by blocking the action of histamine at the H2-receptors located on the parietal cells in the stomach lining. This action reduces the amount of gastric acid secreted by the stomach, thereby alleviating symptoms and promoting the healing of acid-related damage.

What is the usual dosage for Rantac Syrup?

The dosage of Rantac Syrup depends on the condition being treated and the patient's age and weight. For adults, a common dosage for conditions like duodenal or gastric ulcers might be 150 mg (10 ml of 75mg/5ml syrup) twice daily or 300 mg (20 ml of 75mg/5ml syrup) once daily at bedtime. For GERD, it might be 150 mg twice daily. Pediatric dosages (for children 1 month to 16 years) are typically 2 to 10 mg/kg per day, divided into two doses, with a maximum daily dose varying by condition. Always follow your doctor's specific instructions.

What are the possible side effects of Rantac Syrup?

Common side effects can include headache, dizziness, drowsiness, nausea, constipation, stomach pain, and diarrhea. If these side effects bother you or do not go away, consult your doctor. Rarely, more serious side effects such as allergic reactions (rash, itching, hives, swelling, difficulty breathing), kidney or liver problems, pancreatitis, or changes in heart rhythm can occur. Seek immediate medical attention if you experience any severe symptoms.

Is Rantac Syrup safe during pregnancy or breastfeeding?

Rantac Syrup is generally not recommended for use during pregnancy or breastfeeding unless specifically prescribed and closely monitored by a doctor, as there is limited data and potential risks have been noted in animal studies. Ranitidine is known to be secreted in human milk. It is important to consult your doctor before taking this syrup if you are pregnant or breastfeeding.

Can Rantac Syrup be taken with other medications?

Rantac Syrup can interact with certain medications. It can affect the absorption or concentration of drugs such as some antidiabetic medications (e.g., glipizide), medications for insomnia (e.g., triazolam), antifungals (e.g., ketoconazole), some anticancer medications (e.g., gefitinib), HIV medications (e.g., delavirdine, atazanavir), and blood thinners (e.g., warfarin). Always inform your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.

What precautions should be taken while taking Rantac Syrup?

Exercise caution if you have kidney or liver disease, as dose adjustments may be necessary. Inform your doctor if you have a history of porphyria (a rare blood disorder) or gastric cancer, as Rantac Syrup may mask symptoms of cancer. Avoid alcohol consumption while taking Rantac Syrup, as it can increase stomach acid and worsen your symptoms. If you experience dizziness, avoid driving or operating machinery.

What happens if a dose of Rantac Syrup is missed?

If you miss a dose of Rantac Syrup, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Rantac Syrup be stored?

Rantac Syrup should be stored in a cool and dry place, away from direct sunlight, at a temperature below 25°C or 30°C. Keep the bottle tightly capped and out of the sight and reach of children.