Miofree A 4 Mg Tablet (10 Tab)

MIOFREE A 4 MG TABLET

MIOFREE A 4 MG TABLET is a combination medication manufactured by Lupin Ltd., designed to alleviate pain, inflammation, and muscle spasms.

• Composition Each tablet contains Aceclofenac 100 mg and Thiocolchicoside 4 mg. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by inhibiting prostaglandin production. Thiocolchicoside acts as a muscle relaxant, working on the central nervous system to relieve muscle stiffness and improve movement.

• Uses This medicine is prescribed for painful conditions affecting muscles and joints, including muscle spasms, back pain, neck pain, sprains, strains, and joint disorders. It is effective in managing conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, cervical and lumbar spondylosis, sports injuries, and post-operative muscle stiffness.

• Dosage and Administration MIOFREE A 4 MG TABLET should be taken orally, preferably with food to minimize stomach upset. The tablet should be swallowed whole with water and not be crushed or chewed. Dosage varies based on the individual's condition and response to treatment, and it is crucial not to exceed the prescribed dose without consulting a doctor. Typical adult dosage for conditions like osteoarthritis may be one tablet twice daily.

• Side Effects Common side effects may include indigestion, abdominal pain, nausea, diarrhea, dizziness, headache, rash, pruritus, and tiredness. Serious side effects, though less common, can include stomach bleeding, seizures, liver issues (yellow skin/eyes, dark urine), and severe allergic reactions (swelling, breathing difficulty).

• Precautions Caution is advised for patients with liver or kidney problems, heart conditions, a history of stomach ulcers, or bleeding disorders. It is not recommended during the last trimester of pregnancy and should be used with caution during breastfeeding. Alcohol consumption should be avoided as it can increase drowsiness and the risk of stomach bleeding. Due to potential dizziness or drowsiness, patients should avoid driving or operating heavy machinery until they understand how the medicine affects them. Inform your doctor about any other medications being taken, as interactions can occur with antihypertensives, lithium, methotrexate, and cyclosporine.

• Storage Store MIOFREE A 4 MG TABLET in a cool, dry place, ideally below 30°C. Protect it from light and excessive moisture, and keep it out of reach and sight of children.

What is Miofree A 4 MG Tablet used for?

Miofree A 4 MG Tablet is a combination medicine primarily used to relieve pain, inflammation, and muscle spasms associated with various musculoskeletal conditions. It is effective in managing conditions such as back pain, neck pain, joint pain (like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis), muscle stiffness, sprains, strains, and other inflammatory disorders affecting muscles and joints.

How does Miofree A 4 MG Tablet work?

Miofree A 4 MG Tablet contains two active ingredients: Aceclofenac (100 mg) and Thiocolchicoside (4 mg). Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the action of an enzyme called cyclooxygenase (COX), which is responsible for producing prostaglandins—chemicals that cause pain and inflammation in the body. Thiocolchicoside is a muscle relaxant that acts on the central nervous system, specifically at the spinal cord level. It helps reduce muscle spasms and painful muscle contractions by acting on GABA and glycine receptors, thereby relieving muscle stiffness and improving muscle movement.

What is the usual dosage and how should it be taken?

The dosage of Miofree A 4 MG Tablet is determined by your doctor based on your medical condition and response to treatment. It is generally recommended to swallow the tablet whole with a glass of water, without breaking or chewing it. It should always be taken with food to help reduce the risk of stomach upset or irritation. Do not exceed the prescribed dose or duration of treatment without consulting your doctor.

What are the possible side effects of Miofree A 4 MG Tablet?

Common side effects of Miofree A 4 MG Tablet may include indigestion (dyspepsia), abdominal pain, nausea, vomiting, diarrhea, dizziness, headache, rash, and tiredness. If any of these side effects persist or worsen, it is advisable to consult your doctor. Serious, though less common, side effects can include stomach bleeding, seizures, liver issues (such as yellow skin/eyes or dark urine), and severe allergic reactions (like swelling or difficulty breathing).

Is Miofree A 4 MG Tablet safe during pregnancy or breastfeeding?

Miofree A 4 MG Tablet is generally not recommended during pregnancy, especially during the last trimester, as it may cause harm to the fetus. For breastfeeding women, caution is advised as the medicine is excreted in breast milk and may cause adverse effects on the baby; therefore, it is contraindicated in breastfeeding women. Always consult your doctor before taking this medicine if you are pregnant, planning a pregnancy, or breastfeeding.

Can Miofree A 4 MG Tablet be taken with other medications?

Miofree A 4 MG Tablet can interact with several other medications. Taking it with other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) like ibuprofen can increase the risk of gastrointestinal ulcers or bleeding. It may also enhance the effects of anticoagulants like warfarin, potentially increasing bleeding risk. The blood pressure-lowering effect of antihypertensives may be reduced. Plasma levels of mood stabilizers like lithium and toxicity of Disease-Modifying Anti-Rheumatic Drugs (DMARDs) such as methotrexate may increase. Always inform your doctor about all other medicines you are currently taking to avoid potential interactions.

What precautions should be taken while using Miofree A 4 MG Tablet?

Several precautions should be taken:

• Allergies: Avoid if you are allergic to Aceclofenac, Thiocolchicoside, or other NSAIDs.
• Alcohol: Avoid alcohol consumption as it can increase drowsiness and the risk of stomach bleeding.
• Driving/Operating Machinery: This medicine may cause dizziness, drowsiness, or visual disturbances, so avoid driving or operating heavy machinery if you experience these effects.
• Underlying Conditions: Inform your doctor if you have liver disease, kidney disease, heart disease, a history of stomach ulcers or gastrointestinal bleeding, asthma, seizures, or bleeding disorders.
• Children: Miofree A 4 MG Tablet is generally not recommended for use in children below 18 years of age.

What happens if a dose of Miofree A 4 MG Tablet is missed?

If you forget to take a dose of Miofree A 4 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Miofree A 4 MG Tablet be stored?

Miofree A 4 MG Tablet should be stored in a cool, dry place where the temperature stays below 30°C. Keep it protected from light and excessive moisture, and out of the reach and sight of children. Ensure the medicine is used before its expiry date.