Divaa Od 250 Mg (15 Tab)
Not Available
Source ID: 255216
₹165.23
₹124.25
(Inclusive of all taxes)Batch
N2402855
PKG
15 TABLETS
Expiry
2026-09-30
MRP
₹165.23
Stock
18
Discount
24.8%
Description
DIVAA OD 250 MG is a medication manufactured by Intas Pharmaceuticals Ltd., primarily used as an anticonvulsant and mood stabilizer.
Name
- Brand Name: DIVAA OD 250 MG
- Common Name: Divalproex (extended-release)
Composition
The active ingredient in DIVAA OD 250 MG is Divalproex (250 mg). It belongs to a class of medicines known as anticonvulsants or anti-epileptics.
Uses
DIVAA OD 250 MG is prescribed for various medical conditions:
- Epilepsy/Seizures: It is used to treat and prevent different types of seizures, including complex partial seizures, simple absence seizures, and complex absence seizures, by decreasing excessive and abnormal nerve activity in the brain.
- Bipolar Disorder: It is used to treat manic episodes associated with bipolar disorder, helping to stabilize mood and reduce extreme mood swings and agitation. It works by increasing the amount of GABA, a chemical substance that provides a calming effect.
- Migraine Prophylaxis: It is also indicated for the prevention of migraine headaches.
Dosage and Administration
- DIVAA OD 250 MG can be taken with or without food.
- Tablets should be swallowed whole and not crushed or chewed to maintain their extended-release properties.
- Dosage is individualized by a doctor based on the patient's condition and response to treatment.
- For epilepsy, initial adult and pediatric dosage (over 10 years) is typically 10-15 mg/kg/day in divided doses, increasing weekly by 5-10 mg/kg/day, up to a maximum of 60 mg/kg/day.
- For acute manic episodes of bipolar disorder in adults, an initial dose of 25 mg/kg once daily is recommended, with a maximum of 60 mg/kg/day.
- For migraine prophylaxis in adults, an initial dose of 500 mg once daily for 1 week, up to 1000 mg once daily, may be prescribed.
- Do not stop taking the medicine abruptly, as this may worsen seizures.
Side Effects
Common Side Effects:
- Abdominal pain, back pain, constipation, diarrhea
- Dizziness, drowsiness, fatigue
- Nausea, vomiting
- Increased appetite, weight gain
- Headache
- Tremor
- Hair loss
Serious Side Effects (consult doctor immediately):
- Bleeding problems (e.g., unusual bruising, red/purple spots on skin)
- Symptoms of liver damage (e.g., yellowing of skin/eyes, dark urine, loss of appetite, stomach pain)
- Pancreatitis (severe abdominal pain)
- Mood changes, depression, suicidal thoughts or behavior
- Severe skin reactions (e.g., rash, blistering, swelling)
Precautions
- Pregnancy: Contraindicated during pregnancy due to definite risk of developmental defects and decreased IQ levels in the baby. Women of childbearing age should use effective contraception.
- Breastfeeding: Use with caution and only if recommended by a doctor, as it passes into breast milk.
- Liver Disease: Not recommended for patients with active liver disease or significant liver dysfunction. Caution is needed for those with a history of liver problems, with regular monitoring of liver function tests.
- Kidney Disease: Caution is advised for patients with kidney health issues.
- Alcohol: Avoid consuming alcohol as it can increase dizziness and drowsiness and may increase the risk of seizures.
- Driving/Operating Machinery: May cause dizziness and affect thinking and motor skills; avoid these activities until you know how the medicine affects you.
- Interactions: Inform your doctor about all ongoing medications, as DIVAA OD 250 MG can interact with other anticonvulsants, oral contraceptives, anticoagulants (e.g., warfarin), certain antibiotics, and other drugs.
- Children: Care should be taken when administering to children under 2 years due to a higher risk of liver intoxication.
Storage
Store DIVAA OD 250 MG in a cool and dry place, protected from moisture and heat, away from direct sunlight. Keep out of sight and reach of children. The recommended storage temperature is between 10ºC to 25ºC or below 30ºC.
₹165.23
₹124.25
(Inclusive of all taxes)Frequently Asked Questions
Here are some frequently asked questions about DIVAA OD 250 MG:
What is DIVAA OD 250 MG used for?
DIVAA OD 250 MG is primarily used to treat epilepsy (fits or seizures), manage manic episodes associated with bipolar disorder, and prevent migraine headaches. It can also help with symptoms like mood swings and aggression related to bipolar disorder.
How does DIVAA OD 250 MG work?
This medicine contains Divalproex sodium, which works by increasing the levels of a natural chemical called Gamma-aminobutyric acid (GABA) in the brain. GABA helps to reduce excessive nerve cell activity, thereby controlling seizures, stabilizing mood in bipolar disorder, and reducing migraine frequency. It also modulates sodium channels, further stabilizing electrical activity in the brain.
What is the usual dosage for DIVAA OD 250 MG?
The dosage of DIVAA OD 250 MG is determined by your doctor based on your specific medical condition and response to treatment. It should be swallowed whole with a glass of water and not crushed or chewed to maintain its extended-release properties. It can be taken with or without food. For epilepsy, adults and children may start with 15 mg/kg/day in divided doses, gradually increasing to a maximum of 60 mg/kg/day under medical supervision. For mania, a typical starting dose is 750 mg/day in divided doses.
What are the possible side effects of DIVAA OD 250 MG?
Common side effects may include headache, dizziness, nausea, vomiting, stomach pain, diarrhea, shakiness (tremor), tiredness, sleepiness, weight gain, and hair loss. More serious, though rare, side effects can include bleeding problems, high ammonia levels, low body temperature, severe skin rashes, and potentially suicidal thoughts or behaviors. It can also cause liver damage, particularly within the first six months of treatment. Consult your doctor if any side effects persist or worsen.
Is DIVAA OD 250 MG safe during pregnancy or breastfeeding?
DIVAA OD 250 MG is generally not recommended during pregnancy as it is considered unsafe and may cause developmental defects and reduced IQ levels in the unborn baby. Women of childbearing age should use effective contraception while taking this medicine. During breastfeeding, it should be used with caution as Divalproex passes into breast milk. Your doctor will weigh the benefits against the risks to decide if it's appropriate.
Can DIVAA OD 250 MG be taken with other medications?
DIVAA OD 250 MG can interact with various other medicines. It's crucial to inform your doctor about all medications, supplements, or herbal preparations you are taking. Interactions can increase the risk of side effects (e.g., with aspirin, phenobarbital, warfarin) or reduce the effectiveness of DIVAA OD 250 MG (e.g., with certain carbapenem antibiotics). It may also increase the risk of liver problems with medicines like teriflunomide or ketoconazole, or excessive sedation with benzodiazepines.
What precautions should be taken while taking DIVAA OD 250 MG?
Avoid consuming alcohol while on this medication, as it can intensify side effects like drowsiness and dizziness, and increase the risk of liver damage. Due to potential dizziness and drowsiness, avoid driving or operating heavy machinery. This medicine is not recommended if you have known allergies to Divalproex, liver problems, urea cycle disorders, porphyria, or mitochondrial disorders. Inform your doctor if you have kidney problems, systemic lupus erythematosus, bleeding disorders, or a history of pancreatitis. Do not stop taking DIVAA OD 250 MG abruptly, as this can lead to an increase in seizures or a worsening of your condition.
What happens if a dose of DIVAA OD 250 MG is missed?
If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects. Missing doses can also potentially trigger seizures.
How should DIVAA OD 250 MG be stored?
DIVAA OD 250 MG should be stored at room temperature, ideally below 30°C, and protected from moisture and direct heat or sunlight. Always keep the medicine out of the reach and sight of children and pets. Ensure that you do not use any expired or damaged tablets.