Crevast Ez 20mg Tab

CREVAST EZ 20MG TAB

CREVAST EZ 20MG TAB is a combination medication manufactured by ERIS OAKNET HEALTHCARE PVT LTD (also known as Eris Lifesciences Ltd) designed for comprehensive cholesterol management.

• Composition Each tablet contains Ezetimibe 10 mg and Rosuvastatin 20 mg. Rosuvastatin is an HMG-CoA reductase inhibitor (statin) that reduces cholesterol production in the liver, while Ezetimibe is a cholesterol absorption inhibitor that decreases the absorption of cholesterol from the intestines.

• Uses CREVAST EZ 20MG TAB is primarily used to treat high cholesterol levels (dyslipidemia or hyperlipidemia). It helps to lower "bad" cholesterol (LDL) and triglycerides, while increasing "good" cholesterol (HDL). By managing lipid levels, it significantly reduces the risk of cardiovascular events such as heart attack, stroke, and related complications. It is also indicated for the management of mixed dyslipidemia and homozygous familial hypercholesterolemia. This medication is prescribed in conjunction with a heart-healthy diet, regular exercise, and weight management.

• Dosage and Administration The typical recommended dosage is one tablet once daily, with or without food. It is advised to take the medication at the same time each day for optimal effectiveness. The tablet should be swallowed whole and not crushed, broken, or chewed. Dosage may vary and is determined by a healthcare professional based on individual cholesterol levels and risk factors.

• Side Effects Common side effects may include muscle pain, headache, nausea, diarrhea, abdominal pain, fatigue, joint pain, and upper respiratory tract infection. More serious but uncommon side effects can include muscle damage (rhabdomyolysis), elevated liver enzymes, allergic reactions, pancreatitis, gallstones, hepatitis, and increased blood sugar levels.

• Precautions CREVAST EZ 20MG TAB is contraindicated in individuals with active liver disease, unexplained high liver enzymes, severe kidney problems, muscle disorders, or those taking ciclosporin. It is not recommended during pregnancy or breastfeeding. Alcohol consumption should be avoided or limited due to an increased risk of liver problems. Patients with kidney or liver conditions, thyroid disorders, or diabetes should inform their doctor, as dose adjustments or close monitoring may be necessary. This medicine may interact with anticoagulants, HIV protease inhibitors, antacids, and fibrates. Regular blood tests to monitor liver function and creatine kinase (CK) levels are recommended.

• Storage Store CREVAST EZ 20MG TAB at room temperature (below 30°C or 20-25°C), away from direct sunlight and moisture. Keep out of reach of children and pets.

Here are the frequently asked questions about CREVAST EZ 20MG TAB, which contains rosuvastatin and ezetimibe:

What is CREVAST EZ 20MG TAB used for?

CREVAST EZ 20MG TAB is a combination medicine used along with a proper diet to lower high levels of "bad" cholesterol (LDL) and triglycerides in the blood, and to increase "good" cholesterol (HDL). It is also used to treat homozygous familial hypercholesterolemia (HoFH), a genetic condition that causes very high cholesterol levels. By reducing cholesterol, it helps prevent the buildup of fatty deposits in blood vessels, thereby lowering the risk of heart attack, stroke, and related cardiovascular events.

How does CREVAST EZ 20MG TAB work?

CREVAST EZ 20MG TAB contains two active ingredients: rosuvastatin and ezetimibe. Rosuvastatin is a statin that works by blocking an enzyme (HMG-CoA reductase) in the liver, which is essential for cholesterol production, thereby reducing the amount of cholesterol your body makes. Ezetimibe works by inhibiting the absorption of cholesterol from the small intestine, preventing the uptake of dietary and biliary cholesterol. This dual action provides a more significant reduction in cholesterol levels than either medication alone.

What is the usual dosage for CREVAST EZ 20MG TAB?

The typical dosage range for rosuvastatin and ezetimibe combination is one tablet (containing 5 mg to 40 mg of rosuvastatin and 10 mg of ezetimibe) orally once a day. For CREVAST EZ 20MG TAB, it contains 20mg of rosuvastatin and 10mg of ezetimibe. Your doctor will determine the appropriate dose based on your cholesterol levels, risk factors, and other medications you might be taking. It can be taken with or without food. You should swallow the tablet whole and not crush, break, chew, or dissolve it.

What are the possible side effects of CREVAST EZ 20MG TAB?

Common side effects can include headache, nausea, muscle pain, weakness, joint pain, abdominal pain, diarrhea, upper respiratory tract infection, and the common cold. More serious side effects, though rare, can include unexplained muscle pain, tenderness, or weakness (which could indicate myopathy or rhabdomyolysis, a serious muscle problem that can lead to kidney problems), and liver problems (symptoms include upper stomach pain, loss of appetite, dark urine, or yellowing of the skin or eyes). You should contact your doctor immediately if you experience any serious or persistent side effects.

Is CREVAST EZ 20MG TAB safe during pregnancy or breastfeeding?

No, CREVAST EZ 20MG TAB is generally not safe during pregnancy or breastfeeding. Rosuvastatin, one of the active ingredients, may harm an unborn baby. Studies in breastfeeding women have shown harmful infant effects, and breastfeeding is not recommended while using this medication due to the possible risk to the infant. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor immediately.

Can CREVAST EZ 20MG TAB be taken with other medications?

CREVAST EZ 20MG TAB can interact with several medications. It's crucial to inform your doctor about all medicines, including over-the-counter drugs, vitamins, and herbal supplements you are taking. Significant interactions include:

• Cyclosporine or Gemfibrozil: Concomitant use should generally be avoided due to an increased risk of muscle injury.
• Antacids (containing aluminum and magnesium): Take these at least 2 hours after CREVAST EZ to prevent reduced absorption of the medication.
• Bile acid sequestrants (e.g., cholestyramine, colestipol): Take CREVAST EZ at least 2 hours before or 4 hours after taking these medications.
• Certain HIV protease inhibitors and Hepatitis C medications: These can significantly increase rosuvastatin levels, requiring dosage adjustments.
• Warfarin (blood thinner): May alter the effects of warfarin, requiring careful monitoring.
• Red yeast rice products: Avoid due to increased risk of muscle and liver problems.
• Darolutamide and Regorafenib: Doses of CREVAST EZ may need to be reduced when taken with these medications.

What precautions should be taken while taking CREVAST EZ 20MG TAB?

Inform your doctor if you have liver or kidney disease, thyroid problems, diabetes, a history of alcohol abuse, or muscle disorders. Regular liver enzyme tests are recommended. Patients of Asian descent may be more sensitive to rosuvastatin's effects and may need a lower starting dose. Limit alcoholic beverages as they can increase the risk of liver damage. Report any unexplained muscle pain, tenderness, or weakness to your doctor immediately.

What happens if a dose of CREVAST EZ 20MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not take two doses within 12 hours of each other to make up for a missed dose.

How should CREVAST EZ 20MG TAB be stored?

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep it out of the reach of children. Do not keep outdated medicine or medicine no longer needed.