Nugliptin M 500 Mg Tablet (15 Tab)

NUGLIPTIN M 500 MG TABLET (15 TAB) by RPG LIFE SCIENCES LIMITED

Name

• Common Name: Nugliptin M 500 Tablet, Nugliptin M 500/50mg Tablet
• Brand Name: NUGLIPTIN M 500 MG TABLET (15 TAB)

Composition Nugliptin M 500 Tablet contains a combination of two active ingredients:

• Vildagliptin (50 mg)
• Metformin (500 mg)

Uses This medicine is primarily used for the treatment of Type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone, or treatment with a single antidiabetic medication (like metformin or vildagliptin alone), are insufficient to adequately control blood sugar levels. By helping to manage and control blood glucose, Nugliptin M 500 Tablet can reduce the risk of serious diabetes-related complications such as kidney damage, blindness, nerve problems, heart attacks, and strokes.

Dosage and Administration Nugliptin M 500 Tablet should be taken orally, typically two times daily, as advised by a healthcare professional. It is often recommended to take the tablet with food to minimize the likelihood of stomach discomfort. The tablet should be swallowed whole with a glass of water and not be split, crushed, or chewed. Consistent daily intake at the same time is advised for maximum benefit. Dosage is individualized based on the patient's condition, blood sugar levels, and other concurrent medications. It is crucial to adhere to the prescribed diet and exercise plan while on this medication.

Side Effects

• Common Side Effects: Hypoglycemia (low blood sugar), particularly when used with insulin or sulfonylurea, trembling, headache, dizziness, nausea, weakness, gastro-esophageal reflux disease, increased sweating, decreased appetite, shaking or quivering, vomiting, diarrhea, abdominal pain, joint pain, tiredness, constipation, swelling in the hands, ankles, or feet (oedema), and upper respiratory symptoms (such as taste changes, sore throat, nasal congestion).
• Serious Side Effects (Rare): Lactic acidosis (symptoms include vomiting, stomach pain, decreased heartbeat, difficulty breathing, muscle cramps, severe tiredness, or reduced body temperature) and symptoms of an inflamed pancreas (severe and persistent abdominal pain with or without nausea or vomiting). Seek immediate medical attention if these occur.

Precautions

• Contraindications: Avoid use in patients with Type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, congestive heart failure, or known allergies to any of the medication's components.
• Warnings:
  • Inform your doctor if you have a history of pancreatitis, kidney disease, liver disease, heart disease, or low vitamin B12 levels.
  • Alcohol consumption should be limited or avoided, as it can increase the risk of lactic acidosis and impact blood glucose levels.
  • Pregnancy and Breastfeeding: Not generally recommended during pregnancy unless clearly necessary and advised by a doctor due to potential harmful effects on the developing baby. It is probably unsafe for use during breastfeeding as the drug may pass into breastmilk.
  • This medication is not suitable for children and adolescents under 18 years of age and should be used with caution in elderly patients.
  • Blood sugar fluctuations (too low or too high) can affect the ability to drive or operate machinery.
  • Disclose all other medications, including herbal supplements, to your doctor, especially insulin, sulfonylureas, diuretics, beta-blockers, captopril, enalapril, cimetidine, or birth control pills, to avoid potential interactions.
  • Regular monitoring of kidney function and blood sugar levels is essential during treatment.
  • Do not discontinue the medication abruptly without consulting your doctor, as this can lead to increased blood sugar levels and complications.

Storage Store Nugliptin M 500 Tablet in a cool and dry place, protected from direct sunlight, at a temperature below 30°C. Keep it out of the sight and reach of children.

NUGLIPTIN M 500 MG TABLET is a combination medication containing Metformin (500 mg) and Vildagliptin (50 mg), primarily used to manage Type 2 Diabetes Mellitus. It helps control high blood sugar levels when diet and exercise alone, or treatment with either metformin or vildagliptin individually, are not sufficient.

Here are some frequently asked questions about NUGLIPTIN M 500 MG TABLET:

What is NUGLIPTIN M 500 MG TABLET used for?

NUGLIPTIN M 500 MG TABLET is used for the management of high blood sugar levels in adults with Type 2 Diabetes Mellitus. By controlling blood sugar, it helps reduce the risk of serious diabetes-related complications such as kidney damage, blindness, nerve problems, heart attacks, and strokes.

How does NUGLIPTIN M 500 MG TABLET work?

This medicine combines two active ingredients: Metformin and Vildagliptin. Metformin works by decreasing the production of glucose by the liver, reducing the absorption of glucose from the intestines, and improving the body's sensitivity to insulin. Vildagliptin belongs to a class of drugs called DPP-4 inhibitors. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels (glucagon), thereby regulating blood sugar after meals. Together, these actions lead to better control of blood sugar.

What is the usual dosage for NUGLIPTIN M 500 MG TABLET?

The dosage of NUGLIPTIN M 500 MG TABLET is determined by your doctor based on your individual condition, blood sugar levels, and other medications you may be taking. It is generally advised to take the tablet with meals to minimize stomach discomfort, usually twice daily. The tablet should be swallowed whole and not crushed, chewed, or broken. For optimal benefits, it's recommended to take it at the same time each day.

What are the possible side effects of NUGLIPTIN M 500 MG TABLET?

Common side effects can include hypoglycemia (low blood sugar), nausea, diarrhea, vomiting, stomach pain, headache, dizziness, taste changes, and upper respiratory symptoms. More serious but rare side effects include lactic acidosis (symptoms like vomiting, stomach pain, difficulty breathing, muscle cramps) and pancreatitis (severe abdominal pain). If you experience persistent or severe side effects, seek medical attention immediately.

Is NUGLIPTIN M 500 MG TABLET safe during pregnancy or breastfeeding?

NUGLIPTIN M 500 MG TABLET is generally not recommended during pregnancy unless specifically advised by a doctor, as there is limited information on its safety and potential harm to the developing baby. It is also contraindicated during breastfeeding because its components are known to pass into breast milk. Always consult your healthcare provider before using this medication if you are pregnant, planning to conceive, or breastfeeding.

Can NUGLIPTIN M 500 MG TABLET be taken with other medications?

NUGLIPTIN M 500 MG TABLET can interact with various medications. It's crucial to inform your doctor about all medicines you are currently taking, including over-the-counter drugs, vitamins, and herbal supplements. Potential interactions exist with glucocorticoids, beta-2 agonists, diuretics, NSAIDs (non-steroidal anti-inflammatory drugs), ACE inhibitors, cationic medications (like amiloride, digoxin, trimethoprim), iodinated contrast agents, and rifampicin.

What precautions should be taken while taking NUGLIPTIN M 500 MG TABLET?

You should avoid this medication if you have a known allergy to its components, Type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, or certain heart conditions like congestive heart failure. Caution is advised if you have a history of pancreatitis, low vitamin B12 levels, or if you consume alcohol excessively, as it can increase the risk of lactic acidosis. Regular monitoring of blood sugar levels, kidney function, and liver enzymes is essential during treatment. Do not stop taking the medicine abruptly without consulting your doctor, as this can lead to increased blood sugar levels and potential complications.

What happens if a dose of NUGLIPTIN M 500 MG TABLET is missed?

If you miss a dose of NUGLIPTIN M 500 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should NUGLIPTIN M 500 MG TABLET be stored?

NUGLIPTIN M 500 MG TABLET should be stored in a cool, dry place, protected from direct sunlight, moisture, and heat. Keep it out of sight and reach of children. The recommended storage temperature is below 30°C.