Vildambic M 500 Mg Tablet (15 Tab)

VILDAMBIC M 500 MG TABLET

VILDAMBIC M 500 MG TABLET is an oral antidiabetic medication manufactured by Alembic Pharmaceuticals Limited. It is a fixed-dose combination therapy used in the management of type 2 diabetes mellitus.

Composition

VILDAMBIC M 500 MG TABLET contains two active ingredients:

• Vildagliptin: 50 mg
• Metformin Hydrochloride: 500 mg

Uses

VILDAMBIC M 500 MG TABLET is prescribed for adults with type 2 diabetes mellitus. It is used when diet and exercise alone, or treatment with vildagliptin or metformin individually, do not provide adequate glycemic control. Its primary uses include:

• Treating type 2 diabetes mellitus.
• Improving glycemic (blood sugar) control.
• Lowering both fasting and post-meal blood sugar levels.
• Reducing the risk of diabetes-related complications such as kidney damage, nerve damage, vision loss, and heart disease.

Dosage and Administration

VILDAMBIC M 500 MG TABLET is typically taken orally, usually twice daily with meals or as directed by a doctor. It is important to swallow the tablet whole with a glass of water, without crushing, chewing, or breaking it. Consistent daily administration at the same time is recommended for optimal results.

Side Effects

Common side effects may include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain or stomach upset
• Headache
• Hypoglycemia (low blood sugar), especially when used with insulin or sulfonylureas.
• Loss of appetite
• Metallic taste
• Joint pain, tiredness, or constipation

Serious, though less common, side effects include lactic acidosis (a rare but severe condition associated with metformin) and signs of an inflamed pancreas (pancreatitis).

Precautions

• Pregnancy and Breastfeeding: VILDAMBIC M 500 MG TABLET is generally not recommended during pregnancy or breastfeeding. Consult a doctor for safer alternatives.
• Kidney and Liver Disease: Use with caution, and it is contraindicated in severe kidney or liver disease. Regular monitoring of kidney function is essential.
• Heart Conditions: Contraindicated in patients with heart disease or congestive heart failure.
• Alcohol Consumption: Excessive alcohol consumption should be avoided as it may increase the risk of lactic acidosis.
• Children: Not recommended for use in children and adolescents under 18 years of age.
• Drug Interactions: Inform your doctor about all medications, including over-the-counter drugs and supplements, to avoid potential interactions.
• Other Conditions: Not suitable for type 1 diabetes mellitus or diabetic ketoacidosis. Long-term use of metformin can cause Vitamin B12 deficiency.

Storage

Store VILDAMBIC M 500 MG TABLET at room temperature (20-25°C). Protect it from moisture and light. Keep the medicine out of reach of children.

What is Vildambic M 500 MG Tablet used for?

Vildambic M 500 MG Tablet is a combination medication primarily used to manage type 2 diabetes mellitus in adults. It helps control high blood sugar levels when diet and exercise alone, or other single medications like vildagliptin or metformin, are not sufficient. This helps to reduce the risk of serious diabetes-related complications such as kidney damage, nerve problems, heart disease, and vision loss.

How does Vildambic M 500 MG Tablet work?

This tablet contains two active ingredients: Vildagliptin (50 mg) and Metformin (500 mg). Vildagliptin works by inhibiting an enzyme called dipeptidyl peptidase-4 (DPP-4), which increases the levels of natural substances called incretins. This leads to increased insulin secretion and decreased glucagon production, helping to regulate blood sugar, especially after meals. Metformin works by reducing the amount of sugar produced by the liver, decreasing sugar absorption from the gut, and improving the body's sensitivity to insulin, allowing cells to utilize more glucose.

What is the usual dosage for Vildambic M 500 MG Tablet?

The dosage of Vildambic M 500 MG Tablet is determined by your doctor based on your individual condition, blood sugar levels, and response to treatment. It is generally advised to take the tablet orally, usually twice daily, with meals to minimize digestive side effects. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken.

What are the possible side effects of Vildambic M 500 MG Tablet?

Common side effects include diarrhea, nausea, vomiting, abdominal pain, loss of appetite, headache, and upper respiratory tract infections. Some individuals might also experience dizziness, a metallic taste in the mouth, or nasopharyngitis. Hypoglycemia (low blood sugar) can occur, particularly when this medication is used with other anti-diabetic drugs like insulin or sulfonylureas. Rarely, a serious condition called lactic acidosis may occur, which can manifest as vomiting, stomach pain, difficulty breathing, or muscle cramps.

Is Vildambic M 500 MG Tablet safe during pregnancy or breastfeeding?

Vildambic M 500 MG Tablet is generally not recommended during pregnancy unless specifically advised by a doctor, due to limited data on the safety of vildagliptin in pregnant women. Animal studies have shown some reproductive toxicity at high doses. Similarly, it is not recommended for breastfeeding women as its components are known to pass into breast milk. It is crucial to consult your doctor for safer alternatives if you are pregnant, planning to become pregnant, or breastfeeding.

Can Vildambic M 500 MG Tablet be taken with other medications?

Vildambic M 500 MG Tablet can interact with certain medications. For instance, metformin, one of its active ingredients, may interact with cationic medications (e.g., amiloride, digoxin, trimethoprim) leading to increased plasma concentrations of these agents. Iodinated contrast agents, often used in imaging procedures, may cause acute renal failure and lactic acidosis when combined with Vildambic M, so temporary discontinuation of the tablet is often advised during such procedures. CYP3A4 inducers like rifampicin can reduce the effectiveness of vildagliptin. Other interacting medications may include glucocorticoids, beta-2 agonists, diuretics, NSAIDs, and ACE inhibitors. Always inform your doctor about all medications, supplements, and herbal products you are taking.

What precautions should be taken while using Vildambic M 500 MG Tablet?

You should avoid Vildambic M 500 MG Tablet if you have type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, or certain heart conditions like recent heart attack or heart failure. Excessive alcohol consumption should be avoided as it can increase the risk of lactic acidosis. Caution is advised for elderly patients and individuals with a history of pancreatitis or low vitamin B12 levels. Regular monitoring of kidney function and blood sugar levels by a doctor is essential during treatment. Do not stop taking the medication abruptly without consulting your doctor, as this can lead to a rise in blood sugar levels.

What happens if a dose of Vildambic M 500 MG Tablet is missed?

If you miss a dose of Vildambic M 500 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double your dose to compensate for the missed one without consulting your doctor.

How should Vildambic M 500 MG Tablet be stored?

Vildambic M 500 MG Tablet should be stored in a cool, dry place, protected from direct sunlight, heat, and moisture. Ensure the medicine is kept out of the reach of children. Always check and respect the expiry date before taking the medicine.