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Esoz 40mg Tablet
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Esoz 40mg Tablet

Esomeprazole (40mg)

Source ID: 241581

₹228.74

₹172.02

(Inclusive of all taxes)
Delivery Details
Hadapsar

Batch

EZ2PC417

PKG

15 TABLET

Expiry

2026-09-30

MRP

₹228.74

Stock

9

Discount

24.8%

Description

ESOZ 40MG TABLET

ESOZ 40MG TABLET is a medication primarily used to reduce stomach acid production. It is manufactured by Integrace Pvt Ltd.

  • Name:

    • Brand Name: ESOZ 40MG TABLET
    • Common Name: Esomeprazole

  • Composition: Each film-coated tablet contains Esomeprazole Magnesium equivalent to 40 mg of Esomeprazole, typically in the form of enteric-coated pellets.

  • Uses: ESOZ 40MG TABLET, a proton pump inhibitor (PPI), is prescribed for conditions associated with excessive stomach acid.

    • Gastroesophageal Reflux Disease (GERD): Treatment of acid reflux diseases, including healing of erosive esophagitis (inflammation of the food pipe) and symptomatic resolution of heartburn and acid reflux.
    • Peptic Ulcer Disease: Management of stomach and intestinal ulcers, including those caused by excessive use of painkillers (NSAIDs) or stress.
    • Eradication of Helicobacter pylori: Used in combination with specific antibiotics to eliminate H. pylori infection, which can cause ulcers.
    • Zollinger-Ellison Syndrome: Treatment of a rare condition where a tumor leads to increased acid production in the stomach.

  • Dosage and Administration:

    • ESOZ 40MG TABLET is generally taken once daily, ideally at least one hour before a meal, on an empty stomach.
    • Swallow the tablet whole with water; it should not be chewed, crushed, or broken.
    • Typical Dosages:
      • Healing of Erosive Esophagitis: 40 mg once daily for 4 to 8 weeks.
      • Symptomatic GERD: 20 mg once daily for 4 weeks.
      • Maintenance of Healing of Erosive Esophagitis: 20 mg once daily.
      • Zollinger-Ellison Syndrome: Initial dose of 40 mg twice daily, which may be adjusted by a doctor up to 80-160 mg per day.
    • If difficulty swallowing, the capsule contents (pellets) can be mixed with soft applesauce and consumed immediately without chewing.

  • Side Effects:

    • Common Side Effects: Headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth, and vomiting.
    • Serious or Long-Term Side Effects: Prolonged use may lead to a decrease in Vitamin B12 levels and hypomagnesaemia (low magnesium levels), which can manifest as weakness, muscle twitches, irregular heartbeats, or fits. Long-term therapy is also associated with an increased risk of bone fractures (hip, wrist, and spine). Rare instances of skin rash (Subacute cutaneous lupus erythematosus) and signs of kidney problems like decreased urination or edema have been reported.

  • Precautions:

    • Allergy: Contraindicated in patients with known hypersensitivity to Esomeprazole or similar benzimidazoles.
    • Liver Disease: Use with caution in patients with severe liver problems, as dose adjustment may be necessary.
    • Gastric Malignancy: A positive response to ESOZ 40MG TABLET does not rule out the presence of stomach cancer. Patients experiencing unexplained weight loss, frequent vomiting, difficulty swallowing, or blood in vomit should seek immediate medical attention.
    • Drug Interactions: May interact with certain medications including anti-HIV drugs (atazanavir, nelfinavir), digoxin, phenytoin, voriconazole, diazepam, and warfarin, potentially altering their effects.
    • Pregnancy and Breastfeeding: Consult a doctor before use during pregnancy or breastfeeding. It is currently unknown if Esomeprazole passes into breast milk.
    • Children: Generally not recommended for children under 12 years of age, though specific uses for erosive esophagitis in children aged 5-16 may be prescribed by a doctor.
    • Alcohol: Alcohol consumption may increase stomach acid and potentially reduce the medicine's effectiveness.
    • Driving: May cause dizziness, sleepiness, or blurred vision; if these occur, avoid driving or operating machinery.

  • Storage: Store ESOZ 40MG TABLET at room temperature, ideally below 30°C. Keep it in its original packaging to protect it from moisture and light. Ensure the medicine is kept out of the sight and reach of children and pets.

Frequently Asked Questions

What is ESOZ 40MG TABLET used for?

ESOZ 40MG TABLET is primarily used to treat conditions associated with excessive stomach acid production. These include gastroesophageal reflux disease (GERD), peptic ulcer disease (stomach and intestinal ulcers), ulcers caused by the use of certain painkillers (NSAIDs), and Zollinger-Ellison syndrome, a condition where a tumor causes the stomach to produce too much acid. It also helps in healing erosive esophagitis (inflammation of the food pipe) and can be part of a combination therapy to eradicate Helicobacter pylori bacteria, which can cause ulcers.

How does ESOZ 40MG TABLET work?

ESOZ 40MG TABLET contains esomeprazole, which is a proton pump inhibitor (PPI). It works by blocking the action of an enzyme system called the H+/K+-ATPase, also known as the gastric proton pump, located in the cells of the stomach wall. By doing so, it effectively reduces the amount of acid produced in the stomach, providing relief from symptoms and promoting the healing of acid-related damage.

What is the usual dosage for ESOZ 40MG TABLET?

For conditions like healing erosive esophagitis, the typical adult dosage is 20 mg or 40 mg once daily for 4 to 8 weeks. For symptomatic GERD, it's often 20 mg once daily for 4 weeks. ESOZ 40MG TABLET should generally be taken once a day, preferably in the morning, at least one hour before a meal, and swallowed whole with water. It should not be chewed or crushed. Your doctor will determine the exact dose and duration of treatment based on your specific condition.

What are the possible side effects of ESOZ 40MG TABLET?

Common side effects of ESOZ 40MG TABLET include headache, diarrhea, nausea, flatulence (gas), abdominal pain, constipation, and dry mouth. Long-term use (more than 3 months to a year) may lead to certain risks such as low magnesium levels in the blood, vitamin B12 deficiency, and an increased risk of bone fractures (of the hip, wrist, or spine). If you experience persistent or severe side effects, or symptoms like unexplained weight loss, frequent vomiting, difficulty swallowing, or blood in vomit/stools, consult your doctor immediately.

Is ESOZ 40MG TABLET safe during pregnancy or breastfeeding?

The safety of ESOZ 40MG TABLET during pregnancy is not fully established, though limited studies suggest it may be safe. However, it is generally not recommended during pregnancy unless clearly necessary, and the benefits and potential risks should be discussed with a doctor. It is unknown if esomeprazole passes into breast milk, and therefore, breastfeeding should generally be avoided or stopped if the medicine is deemed necessary. Always consult your doctor before taking this medicine if you are pregnant or breastfeeding.

Can ESOZ 40MG TABLET be taken with other medications?

ESOZ 40MG TABLET can interact with certain medications. It may affect the absorption of drugs whose bioavailability is significantly influenced by stomach pH, such as ketoconazole, iron salts, and digoxin. It can also interact with anti-HIV medicines like atazanavir and nelfinavir, potentially decreasing their effectiveness. The clearance of diazepam may be reduced, and the blood-thinning action of warfarin can be increased, raising the risk of bleeding. However, studies show no clinically significant interactions with phenytoin, quinidine, clarithromycin, or amoxicillin when taken alone with esomeprazole. Always inform your doctor about all medications you are taking to avoid potential interactions.

What precautions should be taken while using ESOZ 40MG TABLET?

Before taking ESOZ 40MG TABLET, inform your doctor if you have liver or kidney problems, or a history of allergic reactions to similar medicines. Long-term use may increase the risk of bone fractures and deficiencies in magnesium and Vitamin B12. A positive response to the medicine does not rule out the possibility of stomach cancer, so report any severe stomach pain or blood in stool to your doctor. This medicine may cause dizziness or sleepiness, so caution is advised when driving or operating machinery. Alcohol consumption should be avoided as it can increase stomach acid production and worsen symptoms. ESOZ 40MG TABLET is generally not recommended for children under 12 years of age.

What happens if a dose of ESOZ 40MG TABLET is missed?

If you miss a dose of ESOZ 40MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should ESOZ 40MG TABLET be stored?

ESOZ 40MG TABLET should be stored in a dry area at a temperature not exceeding 30°C. It should be shielded from moisture and light, and kept out of the reach of children and pets.