Ziten M 20/1000 Tab (15 Tab)

ZITEN M 20/1000 TAB

ZITEN M 20/1000 TAB is an antidiabetic medication manufactured by Glenmark Pharmaceuticals Ltd..

• Name

  • Brand Name: ZITEN M 20/1000 TAB
  • Common Name: Metformin and Teneligliptin tablets

• Composition Each tablet contains a combination of two active ingredients:

  • Teneligliptin: 20 mg
  • Metformin Hydrochloride: 1000 mg

• Uses ZITEN M 20/1000 TAB is primarily used for the management of type 2 diabetes mellitus in adults. It helps to control high blood sugar levels by reducing glucose production in the liver, decreasing glucose absorption from the intestines, and increasing the body's sensitivity to insulin. This medication is most effective when used in conjunction with a balanced diet and regular physical activity, and also helps in reducing the risk of diabetes-related complications.

• Dosage and Administration The tablet should be swallowed whole with a glass of water, without crushing, chewing, or breaking it. It is generally recommended to take this medicine with your evening meal to minimize potential side effects. The typical dosage is once daily, but it is crucial to follow the specific dose and duration prescribed by your doctor. Do not adjust or discontinue the medication without consulting a healthcare professional.

• Side Effects Common side effects may include upper respiratory tract infection, nasopharyngitis, diarrhea, headache, back pain, joint pain, nausea, vomiting, stomach ache, and altered taste sensations. More serious side effects can include lactic acidosis, a rare but severe condition characterized by symptoms such as muscle pain, dizziness, difficulty breathing, and stomach pain. Long-term use of metformin may also lead to Vitamin B12 deficiency. Hypoglycemia (low blood sugar) can occur, especially when combined with other antidiabetic medicines or if meals are skipped.

• Precautions Caution is advised for patients with kidney or liver problems, heart conditions, and those with a history of severe infections or trauma. It is not recommended for individuals with severe renal impairment, metabolic acidosis, type 1 diabetes, or diabetic ketoacidosis. Excessive alcohol consumption should be avoided as it increases the risk of lactic acidosis. Pregnant or breastfeeding individuals should consult their doctor before using this medicine. Regular monitoring of blood sugar levels and kidney function is recommended during therapy.

• Storage Store ZITEN M 20/1000 TAB below 30°C, protected from light and moisture. Keep the medicine in a cool, dry place, away from direct sunlight and heat exposure. It should always be kept out of the reach of children.

ZITEN M 20/1000 TAB is a medication used to manage type 2 diabetes mellitus. It combines two active ingredients, Metformin and Teneligliptin, to help control blood sugar levels.

Here are some frequently asked questions about ZITEN M 20/1000 TAB:

What is ZITEN M 20/1000 TAB used for?

ZITEN M 20/1000 TAB is primarily used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It is often prescribed when diet and exercise alone, or treatment with metformin alone, have not provided adequate glycemic control.

How does ZITEN M 20/1000 TAB work?

This medicine contains two active ingredients: Metformin and Teneligliptin. Metformin works by reducing the production of glucose in the liver, decreasing the absorption of glucose from the intestines, and improving the body's sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases the levels of natural incretin hormones, which, in turn, enhance insulin secretion from the pancreas and reduce glucagon levels, particularly after meals. Together, these actions help achieve better control of blood sugar.

What is the usual dosage for ZITEN M 20/1000 TAB?

ZITEN M 20/1000 TAB is typically taken once daily, or as advised by your doctor. It is recommended to swallow the tablet whole with a glass of water, preferably after meals, to help reduce stomach upset. Your doctor will determine the correct dose and duration of therapy based on your age, body weight, and medical condition.

What are the possible side effects of ZITEN M 20/1000 TAB?

Common side effects may include nausea, vomiting, diarrhea, headache, stomach ache, and low blood sugar (hypoglycemia). A serious but rare side effect is lactic acidosis, characterized by symptoms like muscle pain, dizziness, tiredness, difficulty breathing, and stomach pain, which requires immediate medical attention. Long-term use may also lead to Vitamin B12 deficiency.

Is ZITEN M 20/1000 TAB safe during pregnancy or breastfeeding?

Pregnancy: There is limited information on the effect of Ziten M Tablet during pregnancy, and it should only be used if the potential benefit justifies the potential risk to the fetus. Consult your doctor if you are pregnant or planning to conceive. Breastfeeding: ZITEN M 20/1000 TAB is generally not recommended for use in breastfeeding mothers as its components may pass into breast milk and cause unwanted effects in nursing babies.

Can ZITEN M 20/1000 TAB be taken with other medications?

ZITEN M 20/1000 TAB can interact with several medications. Inform your doctor about all medicines you are taking, including:

• Other anti-diabetic medications (e.g., glimepiride, insulin).
• Carbonic anhydrase inhibitors (e.g., acetazolamide, topiramate), which can increase the risk of lactic acidosis.
• Metformin clearance reducers (e.g., ranolazine, vandetanib, dolutegravir, cimetidine).
• Iodine contrast media (used during X-rays), requiring temporary discontinuation of Ziten M.
• Bronchodilators (e.g., salbutamol, terbutaline).
• Corticosteroids (e.g., hydrocortisone, prednisolone).
• Diuretics (e.g., furosemide, hydrochlorothiazide).
• Certain heart rhythm medications (e.g., quinidine, sotalol, procainamide, amiodarone).

What precautions should be taken while taking ZITEN M 20/1000 TAB?

• Alcohol: Avoid excessive alcohol intake as it can increase the risk of lactic acidosis and low blood sugar.
• Medical Conditions: Inform your doctor if you have liver, kidney, or heart problems, severe infections, or are due to undergo surgery. It is contraindicated in severe renal impairment, type 1 diabetes, diabetic ketoacidosis, and severe heart problems.
• Monitoring: Your doctor may regularly monitor blood sugar levels and kidney function during treatment.

What happens if a dose of ZITEN M 20/1000 TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should ZITEN M 20/1000 TAB be stored?

Store ZITEN M 20/1000 TAB in a cool, dry place, away from direct sunlight and heat exposure, ideally below 25°C. Keep it out of the sight and reach of children.