Pruease 2 Mg Tablet (10 Tab)

PRUEASE 2 MG TABLET

Name

Brand Name: PRUEASE 2 MG TABLET

Composition

Active Ingredient: Prucalopride (2mg) Prucalopride is a selective serotonin (5-HT4) receptor agonist and a gastrointestinal prokinetic agent. It works by stimulating specific receptors in the intestinal walls, which enhances gut motility and improves the movement of food through the digestive tract.

Uses

PRUEASE 2 MG TABLET is primarily prescribed for the treatment of:

• Chronic constipation in adults for whom conventional laxatives have not provided adequate relief.
• Chronic idiopathic constipation, a long-term constipation with no known underlying cause. It helps to restore natural bowel movement, ease the passage of stools, and reduce associated symptoms like bloating, acidity, and general digestive discomfort. The medicine is also beneficial in cases of gastroparesis associated with constipation.

Dosage and Administration

The typical recommended adult dose is 2 mg once daily. PRUEASE 2 MG TABLET should be taken orally, with or without food. For best results and consistency, it is advisable to take the medicine at a fixed time each day. The tablet should be swallowed whole and not chewed, crushed, or broken. The duration of treatment will be determined by a healthcare professional based on the individual's condition and response to the medicine. Do not discontinue the medication early without consulting your doctor, as symptoms may recur or worsen. PRUEASE 2 MG TABLET is not recommended for use in children and adolescents below 18 years of age.

Side Effects

Common side effects associated with PRUEASE 2 MG TABLET include:

• Headache
• Nausea
• Abdominal pain
• Diarrhea
• Decreased appetite
• Dizziness
• Indigestion (dyspepsia)

Most of these side effects are usually mild, temporary, and tend to resolve as the body adjusts to the medication. If any side effects persist, worsen, or cause concern, it is important to consult a doctor. In case of diarrhea, it is recommended to drink plenty of fluids to prevent dehydration.

Precautions

• Allergies: Avoid taking PRUEASE 2 MG TABLET if you have a known allergy to prucalopride or any of its ingredients.
• Gastrointestinal Conditions: This medicine is contraindicated in patients with perforation or obstruction of the gut wall, severe inflammatory conditions of the intestinal tract such as Crohn's disease, ulcerative colitis, or toxic megacolon/megarectum, and bleeding ulcers of the stomach.
• Kidney and Liver Impairment: Use with caution in patients with severe kidney or liver disease, as dose adjustments may be necessary. It is not recommended for patients undergoing renal dialysis.
• Pregnancy and Breastfeeding: PRUEASE 2 MG TABLET is not recommended during pregnancy, and effective contraception should be used while on this medication. It is also probably unsafe and generally advised to avoid during breastfeeding. Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.
• Other Medical Conditions: Inform your doctor if you have heart disease, serious lung disease, endocrine system disorders, neurological or psychiatric disorders (including suicidal tendencies or mood disorders), cancer, or AIDS.
• Driving and Operating Machinery: PRUEASE 2 MG TABLET may cause dizziness and tiredness, especially during the initial days of treatment, which could affect the ability to drive or operate machinery. Exercise caution and only drive if you feel alert.
• Alcohol: Consult your doctor regarding alcohol consumption as it may increase the risk of side effects.
• Drug Interactions: Inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, you are taking, as some may interact with PRUEASE 2 MG TABLET.

Storage

Store PRUEASE 2 MG TABLET in a cool and dry place, ideally below 30°C. Keep it away from direct light, heat, and moisture. Ensure the medicine is kept out of the reach and sight of children and pets. Always check the expiry date and use the medicine before it expires.

PRUEASE 2 MG TABLET contains prucalopride, a medication primarily used to treat chronic idiopathic constipation (CIC) in adults. It is typically prescribed when other laxatives have not provided adequate relief.

Here are some frequently asked questions about PRUEASE 2 MG TABLET:

What is PRUEASE 2 MG TABLET used for?

PRUEASE 2 MG TABLET is used to treat chronic idiopathic constipation (CIC) in adults. CIC is a condition where a person experiences infrequent, difficult, or incomplete bowel movements for at least three months, without a known underlying cause. It is prescribed when conventional laxatives have failed to provide adequate relief.

How does PRUEASE 2 MG TABLET work?

The active ingredient, prucalopride, is a selective serotonin type 4 (5-HT4) receptor agonist. It works by stimulating specific receptors in the gastrointestinal tract, which leads to the release of acetylcholine. This in turn enhances colonic peristalsis (the rhythmic muscle contractions that move stool) and increases bowel motility, helping to restore normal bowel function and facilitate defecation.

What is the usual dosage of PRUEASE 2 MG TABLET?

For adults with chronic idiopathic constipation, the usual recommended dose is 2 milligrams (mg) once a day, taken orally with or without food. For patients with severe renal impairment (creatinine clearance less than 30 mL/min), a lower dose of 1 mg once daily is recommended. Always take this medicine exactly as directed by your doctor.

What are the possible side effects of PRUEASE 2 MG TABLET?

Common side effects include headache, abdominal pain, nausea, diarrhea, abdominal distension, dizziness, vomiting, and fatigue. If you experience persistent or worsening side effects, consult your doctor. Serious but rare side effects include severe allergic reactions (e.g., hives, difficulty breathing, swelling of the face, lips, tongue, or throat) and changes in mood or behavior, including persistent worsening of depression, suicidal thoughts, or self-harming ideation. If any of these serious side effects occur, discontinue the medication and seek immediate medical attention.

Is PRUEASE 2 MG TABLET safe during pregnancy or breastfeeding?

PRUEASE 2 MG TABLET is generally not recommended during pregnancy, and women of childbearing potential should use effective contraception during treatment. Prucalopride is excreted into breast milk. While effects on breastfed infants are not anticipated at therapeutic doses, it is advisable to discuss with your healthcare provider whether to discontinue breastfeeding or discontinue the medication, considering the benefits to both mother and child. Monitor breastfed infants for symptoms like diarrhea.

Can PRUEASE 2 MG TABLET be taken with other medications?

It is crucial to inform your doctor and pharmacist about all prescription and non-prescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. While interactions are not always expected, some medications may decrease the excretion rate of prucalopride or affect its efficacy. For example, Ketoconazole and Cyclosporine may interact with prucalopride. Additionally, if you experience diarrhea when starting prucalopride, the effectiveness of oral contraceptives might be reduced, requiring additional precautions. Your doctor may need to adjust doses or monitor you carefully.

What precautions should be taken while using PRUEASE 2 MG TABLET?

Do not take PRUEASE 2 MG TABLET if you have a history of hypersensitivity to prucalopride, are undergoing renal dialysis, or have intestinal perforation, obstruction, obstructive ileus, or severe inflammatory conditions of the intestinal tract such as Crohn's disease, ulcerative colitis, or toxic megacolon/megarectum. Monitor for new onset or worsening of depression, suicidal thoughts, or unusual changes in mood or behavior. Use with caution if you have severe kidney or liver disease. As this medication may cause dizziness or fatigue, avoid driving or operating machinery until you know how it affects you.

What happens if a dose of PRUEASE 2 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should PRUEASE 2 MG TABLET be stored?

Store PRUEASE 2 MG TABLET in a closed container at room temperature (20–25°C, with excursions permitted to 15–30°C), away from heat, moisture, and direct light. Keep it from freezing and store it in its original container, out of the reach of children.