Pregaba-m Sr 75 Tablet (15 Tab)

PREGABA-M SR 75 TABLET

Name

• Common Name: PREGABA-M SR 75 TABLET
• Brand Name: PREGABA-M SR 75 TABLET (manufactured by Torrent Pharmaceuticals Ltd.)

Composition

PREGABA-M SR 75 TABLET is a combination medication containing two active ingredients:

• Pregabalin: 75 mg (Sustained Release)
• Methylcobalamin: 1500 mcg (a form of Vitamin B12)

Uses

This medication is primarily used for the treatment of neuropathic pain (nerve pain), which results from damage to the nerves. It is prescribed for various conditions, including:

• Diabetic peripheral neuropathy
• Post-herpetic neuralgia (pain after shingles)
• Pain resulting from spinal cord injury
• Trigeminal neuralgia
• Multiple sclerosis
• Chemotherapy-induced neuropathy It may also be used to control seizures and treat musculoskeletal pain (fibromyalgia). Pregabalin works by decreasing pain signals, while Methylcobalamin helps in nerve regeneration and protection.

Dosage and Administration

PREGABA-M SR 75 TABLET is typically taken orally with water, usually once or twice a day. It can be taken with or without food, but some sources suggest taking it preferably at bedtime.

• Swallow the tablet whole; do not crush, chew, or break it.
• It is advised to take the medicine at the same time each day to maintain a consistent level in the body.
• The dosage may vary based on the patient's condition and response to treatment, so it is crucial to follow the doctor's instructions.
• Do not stop taking this medication suddenly, as it can lead to withdrawal symptoms and worsen the condition.

Side Effects

Common side effects that may occur include:

• Dizziness
• Drowsiness/Sleepiness
• Headache
• Nausea and Vomiting
• Increased appetite and Weight gain
• Blurred vision and other vision problems
• Fatigue
• Dry mouth
• Constipation or Diarrhea
• Fluid retention and swelling of hands or feet
• Mood changes

Serious side effects are less common but can include severe allergic reactions (skin rash, itching, swelling of face/lips/throat, difficulty breathing). Patients with pre-existing heart conditions may have an increased risk of heart failure.

Precautions

• Alcohol: Avoid consuming alcohol while taking this medicine, as it can increase dizziness and drowsiness.
• Driving/Operating Machinery: PREGABA-M SR 75 TABLET may cause dizziness, drowsiness, or blurred vision, so avoid driving or operating machinery until you know how the medication affects you.
• Medical Conditions: Inform your doctor about any pre-existing conditions such as heart, liver, or kidney disease, diabetes, or a history of alcoholism or drug abuse.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It is generally advised not to take this medicine during pregnancy or while breastfeeding unless the benefits outweigh the risks.
• Discontinuation: Do not stop taking the medication abruptly without consulting your doctor, as this can cause withdrawal symptoms.
• Weight Gain: Regular exercise and a balanced diet may help manage potential weight gain.
• Elderly Patients: Use with caution in elderly patients due to an increased risk of accidental injury (falls) from dizziness and sleepiness.
• Pediatric Use: Not recommended for individuals under 18 years of age.

Storage

Store PREGABA-M SR 75 TABLET in a cool and dry place, away from direct sunlight and moisture. Keep it out of sight and reach of children and pets. Store below 25°C or between 10ºC to 25ºC.

Here are some frequently asked questions about PREGABA-M SR 75 TABLET:

1. What is PREGABA-M SR 75 TABLET used for?

PREGABA-M SR 75 TABLET is primarily used to manage neuropathic pain, which is nerve pain caused by nerve damage or dysfunction. This includes conditions such as diabetic peripheral neuropathy, post-herpetic neuralgia (pain after shingles), trigeminal neuralgia, pain from spinal cord injury, multiple sclerosis, and chemotherapy-induced neuropathy. It may also provide relief for sciatica and other nerve-related pain conditions.

2. How does PREGABA-M SR 75 TABLET work?

This medicine contains two active components: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that reduces nerve-related pain by modulating calcium channel activity in nerve cells, thereby inhibiting pain signals. Methylcobalamin, a form of Vitamin B12, supports nerve regeneration, protects nerve fibers by helping produce myelin (the protective layer around nerves), and improves nerve conduction.

3. What is the usual dosage for PREGABA-M SR 75 TABLET?

The exact dosage should be determined by your doctor based on your condition and response to treatment. Generally, it is often recommended to take one tablet twice a day, orally with water. It can be taken with or without food, but taking it at the same time each day (sometimes preferably at bedtime) helps maintain a consistent level in your body. Do not crush, chew, or break the tablet.

4. What are the possible side effects of PREGABA-M SR 75 TABLET?

Common side effects may include dizziness, drowsiness, headache, dry mouth, blurred vision, constipation, increased appetite, weight gain, and fatigue. Some people may also experience nausea, vomiting, fluid retention, or mood changes. If any side effects persist or worsen, you should consult your doctor.

5. Is PREGABA-M SR 75 TABLET safe during pregnancy or breastfeeding?

PREGABA-M SR 75 TABLET is generally advised against during pregnancy due to limited data on its safety and potential harm to the fetus. For breastfeeding mothers, it is probably unsafe as it may pass into human milk and could harm the newborn baby. It is crucial to consult your doctor if you are pregnant, planning pregnancy, or breastfeeding. Women of childbearing age may be advised to use effective contraception.

6. Can PREGABA-M SR 75 TABLET be taken with other medications?

You should inform your doctor about all medications you are currently taking. This medicine should be used with caution with Central Nervous System (CNS) depressants (like opioids, benzodiazepines, or barbiturates) as it can amplify their sedative effects, potentially leading to increased drowsiness. Taking it with certain diabetes medications (like pioglitazone or rosiglitazone) may lead to weight gain and fluid buildup, which can worsen heart failure in some patients.

7. What precautions should be taken while using PREGABA-M SR 75 TABLET?

Avoid consuming alcohol while taking this medicine as it can increase side effects like dizziness and drowsiness. Do not drive or operate heavy machinery until you know how the medication affects you, as it can cause dizziness, drowsiness, or blurred vision. Caution is advised if you have kidney or heart problems, or liver disease. It is important not to stop taking this medication abruptly without consulting your doctor, as it can lead to withdrawal symptoms. Monitor for any unusual changes in mood or behavior, including suicidal thoughts.

8. What should I do if I miss a dose of PREGABA-M SR 75 TABLET?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

9. How should PREGABA-M SR 75 TABLET be stored?

Store the medicine in a cool and dry place, away from direct sunlight and moisture. The recommended storage temperature is below 25°C or 30°C. Keep it out of sight and reach of children and pets.

10. Can I stop taking PREGABA-M SR 75 TABLET once my pain is relieved?

No, you should not stop taking PREGABA-M SR 75 TABLET abruptly, even if your symptoms improve. Stopping suddenly can lead to withdrawal symptoms such as anxiety, difficulty sleeping, nausea, pain, and sweating. Your doctor will advise you on how to gradually reduce the dose before discontinuing the medication completely.