Nefrosave Forte Tablet (15 Tab)

NEFROSAVE FORTE TABLET

NEFROSAVE FORTE TABLET is a medication manufactured by FOURRTS (INDIA) LABORATORIES PVT. LIMITED, primarily used to manage chronic kidney disease (CKD).

• Name:

  • Brand Name: NEFROSAVE FORTE TABLET

• Composition:

  • Each film-coated tablet contains:
    • Acetylcysteine USP: 300 mg
    • Pyridoxamine Dihydrochloride (a derivative of Vitamin B6): 50 mg

• Uses: NEFROSAVE FORTE TABLET is primarily used in the management of chronic kidney disease (CKD), particularly in individuals with associated conditions such as high blood pressure and diabetes. It helps to delay the progression of kidney damage by reducing oxidative stress and inflammation. Specific uses include:

  • Managing Chronic Kidney Disease (CKD), including diabetic nephropathy and glomerulonephritis.
  • Supporting kidney health and function by protecting kidney cells from damage.
  • Assisting in the metabolism of fats, carbohydrates, and proteins to maintain energy balance in CKD patients.
  • May be used as a preventive measure for individuals at risk of developing kidney problems.
  • Also indicated for the management of radiocontrast-induced nephropathy and as an antidote for paracetamol poisoning.

• Dosage and Administration:

  • NEFROSAVE FORTE TABLET should be taken as directed by a healthcare professional.
  • The recommended dose is typically 1-2 tablets twice daily, after food.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • It is crucial to take the medication regularly and at the same time each day for optimal results.
  • Do not discontinue the medication without consulting your doctor, even if symptoms improve.

• Side Effects: Common side effects may include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain Serious, though less common, side effects that require immediate medical attention include allergic reactions (difficulty breathing, chest tightness, rash, itching, hives, swelling of the lips, tongue, or face), fever, chills, and mouth or skin blisters.

• Precautions:

  • Inform your doctor about any allergies to Acetylcysteine, Pyridoxamine dihydrochloride, or any other ingredients in the tablet.
  • Pregnancy and Breastfeeding: Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding, as safety information is limited.
  • Alcohol: It is generally recommended to avoid or limit alcohol consumption while taking this medication as it may interact with the medicine.
  • Liver Disease: Patients with severe liver problems should consult their doctor, as dose adjustments may be required.
  • Children: Not recommended for use in children under 2 years of age.
  • Other Conditions: Inform your doctor if you have bronchial asthma, gastric or duodenal ulceration, severe infections, tuberculosis, intestinal ulcers, diverticulitis, cancer, low white blood cells, platelets, or elevated liver enzymes.
  • Drug Interactions: Disclose all other medications, supplements (including vitamins A, E, K, and minerals like phosphorus), or herbal products you are taking to your doctor to prevent potential adverse interactions.
  • Vaccinations: Discuss with your doctor if you have recently been vaccinated or are planning a vaccination, as certain live vaccines should not be given while taking this medicine.

• Storage:

  • Store in a cool and dry place, away from heat, moisture, and direct light.
  • Keep the medicine below 30°C (or between 10ºC to 25ºC).
  • Do not freeze.
  • Keep out of the reach and sight of children.

What is Nefrosave Forte Tablet used for?

Nefrosave Forte Tablet is primarily used to manage Chronic Kidney Disease (CKD), particularly in individuals also affected by high blood pressure and diabetes. It helps to slow the progression of kidney damage, improve kidney function, and assist in maintaining energy balance in patients with kidney disease. It may also be prescribed as a preventive measure for those at risk of developing kidney problems.

How does Nefrosave Forte Tablet work?

Nefrosave Forte Tablet contains two active ingredients: Acetylcysteine and Pyridoxamine dihydrochloride. Acetylcysteine acts as an antioxidant, protecting body tissues from harmful free radicals, especially in people with CKD and those undergoing dialysis. Pyridoxamine dihydrochloride, a derivative of vitamin B6, plays a crucial role in the metabolism of fats, carbohydrates, and proteins, thereby helping to maintain energy balance in kidney disease patients. Together, these ingredients work to reduce oxidative stress and inflammation in the kidneys.

What is the usual dosage for Nefrosave Forte Tablet?

The recommended dose of Nefrosave Forte Tablet is typically 1-2 tablets taken twice daily after food, or as directed by your physician. It should be swallowed whole with a glass of water, and not crushed, chewed, or broken. The specific dosage and duration of treatment may vary based on your individual condition and response to the medication, so it's important to follow your doctor's instructions.

What are the possible side effects of Nefrosave Forte Tablet?

Common side effects of Nefrosave Forte Tablet include nausea, vomiting, diarrhea, and abdominal pain. Most of these side effects are temporary and usually resolve over time. In some cases, drowsiness and skin rashes have also been reported. If these side effects persist or worsen, you should consult your doctor. Serious but rare side effects, such as allergic reactions (difficulty breathing, chest tightness, rash, itching, hives, swelling in the lips, tongue, or face), fever, chills, or mouth/skin blisters, require immediate medical attention.

Is Nefrosave Forte Tablet safe during pregnancy or breastfeeding?

Limited safety data is available regarding the use of Nefrosave Forte Tablet during pregnancy and breastfeeding. It is highly recommended to consult your doctor before taking this medication if you are pregnant, planning to become pregnant, or breastfeeding. Your doctor will assess the potential benefits against any possible risks to determine if the medication is appropriate for you.

Can Nefrosave Forte Tablet be taken with other medications?

Nefrosave Forte Tablet can generally be taken safely with oral anti-diabetic medications, cardiovascular medications, and medications for hypertension. However, it is crucial to inform your doctor about all other medications, supplements, and herbal products you are currently taking, as some interactions are possible. For instance, it may interact with certain antitussives, antibiotics (such as Gentamicin, Streptomycin, and Tetracycline), and Nitroglycerin.

What precautions should be taken while using Nefrosave Forte Tablet?

Before taking Nefrosave Forte Tablet, inform your doctor if you have any known allergies to its ingredients (Acetylcysteine or Pyridoxamine dihydrochloride). Exercise caution and consult your doctor if you have a history of liver disease, asthma, or gastrointestinal ulcers/bleeding. It is advisable to avoid or limit alcohol consumption while on this medication. Do not crush, chew, or break the tablet. Inform your doctor about any skin reactions or irritation you've experienced with other medicines. Additionally, discuss any recent or planned vaccinations with your doctor. This medicine is not recommended for children under 2 years of age, and caution is advised for older patients.

What happens if a dose of Nefrosave Forte Tablet is missed?

If you miss a dose of Nefrosave Forte Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects.

How should Nefrosave Forte Tablet be stored?

Nefrosave Forte Tablet should be stored in a cool and dry place, away from direct sunlight, heat, and moisture. The ideal storage temperature is below 30°C (or between 10°C and 25°C). It is important to keep the medication out of the sight and reach of children. Do not freeze the tablets.