Butrum 1mg Inj

BUTRUM 1MG Injection

BUTRUM 1MG Injection is a medication manufactured by Aristo Pharmaceuticals Pvt Ltd.

• Composition BUTRUM 1MG Injection contains Butorphanol (1mg) as its active ingredient. Butorphanol is classified as an opioid agonist/antagonist analgesic.

• Uses BUTRUM 1MG Injection is primarily used for the management of moderate to severe pain where opioid analgesics are deemed appropriate. It is also prescribed for:

  • Pre-anaesthetic medication and as a supplement to balanced anaesthesia.
  • Relief of pain during labor.
  • Post-surgical pain management.
  • Migraine headaches.
  • Relief from muscle pain, bone pain, and toothache.
  • As an antitussive (cough suppressant) agent.

• Dosage and Administration BUTRUM 1MG Injection is administered by healthcare professionals either into a muscle (intramuscularly) or a vein (intravenously). Self-administration of this medicine is not recommended. The dosage and duration of treatment are determined by the doctor based on the patient's condition and response. It is typically given once every 3-4 hours as needed for pain relief.

• Side Effects Common side effects of BUTRUM 1MG Injection include:

  • Headache, dizziness, sleepiness, or drowsiness.
  • Nausea and vomiting.
  • Constipation.
  • Injection site reactions (such as pain, redness, and swelling).
  • Dry mouth, fatigue, and lethargy. More serious, though less common, side effects can include difficulty breathing, shortness of breath, chest tightness, wheezing, blurred vision, and irregular heartbeat.

• Precautions

  • Drowsiness: BUTRUM 1MG Injection can cause drowsiness and dizziness; therefore, operating vehicles or machinery should be avoided until alertness returns to normal.
  • Alcohol Interaction: Alcohol consumption is not recommended during treatment as it can exacerbate sedative effects.
  • Medical Conditions: Use with caution in patients with kidney or liver disease, heart conditions, respiratory problems (e.g., asthma, respiratory depression), hypertension, head injury, increased intracranial pressure, opioid dependency, or a history of substance abuse.
  • Pregnancy and Breastfeeding: It is a Category C pregnancy risk medicine and should be used with caution in pregnant and breastfeeding women only if clearly necessary, as it can pass into breast milk.
  • Age Restrictions: Not recommended for patients under 18 years of age and should be used with caution in elderly patients.
  • Dependency: Butorphanol has the potential for abuse and addiction, and sudden discontinuation in physiologically dependent patients can cause withdrawal symptoms.

• Storage Store BUTRUM 1MG Injection in a cool and dry place, preferably at 20 to 25°C or below 30°C. It should be kept away from direct sunlight, excess moisture, and heat, in an airtight container and out of reach of children.

BUTRUM 1MG INJ, which contains Butorphanol, is a narcotic analgesic primarily used for managing moderate to severe pain. It is administered as an injection, typically by healthcare professionals.

What is BUTRUM 1MG INJ used for?

BUTRUM 1MG INJ is used to treat moderate to severe pain, including post-surgical pain, muscle pain, bone pain, toothache, and migraine headaches. It can also be used as a pre-anaesthetic medication, as a supplement to balanced anesthesia, and to provide pain relief during labor. Additionally, it acts as a cough suppressant (antitussive) and can help prevent vomiting (antiemetic).

How does BUTRUM 1MG INJ work?

BUTRUM 1MG INJ works by blocking the transmission of pain signals in the brain and spinal cord. Its active ingredient, Butorphanol, is a mixed opioid agonist-antagonist, meaning it binds to both µ-opiooid and k-opioid receptors in the central nervous system to reduce pain perception.

What is the usual dosage of BUTRUM 1MG INJ?

BUTRUM 1MG INJ is typically administered by a healthcare professional into a muscle (intramuscularly) or vein (intravenously). The dosage and duration of treatment are determined by the doctor based on the patient's condition, age, body weight, and response to the medication. For pain relief, it is usually given once every 3-4 hours as needed. When used before surgery, the usual adult dose might be 2 mg intramuscularly 60-90 minutes prior to the procedure, or 2 mg intravenously shortly before induction, with increments during anesthesia. It is important not to self-administer this medicine.

What are the possible side effects of BUTRUM 1MG INJ?

Common side effects include headache, dizziness, sleepiness (drowsiness), nausea, vomiting, constipation, and reactions at the injection site (such as pain, redness, and swelling). More serious side effects can include breathing difficulties, shortness of breath, changes in heartbeat, and confusion. If any side effects persist or worsen, medical advice should be sought.

Is BUTRUM 1MG INJ safe during pregnancy or breastfeeding?

Pregnancy: BUTRUM 1MG INJ is classified as a Category C pregnancy risk medicine. Several studies suggest it may affect the baby's development, and prolonged use or use near term may be Category D. It should be used with caution and only if clearly necessary, as it might lead to physical dependence and neonatal opioid withdrawal syndrome in newborns. It is generally advised to consult a doctor before using it during pregnancy.

Breastfeeding: BUTRUM 1MG INJ should be used with caution in breastfeeding women if clearly necessary, as it can pass into breast milk in clinically insignificant amounts. Human studies suggest it does not pass into breast milk in a significant amount and is not harmful to the baby, but the baby should be monitored for excessive sleepiness and weight gain. Consult your doctor before breastfeeding while on this medication.

Can BUTRUM 1MG INJ be taken with other medications?

It is crucial to inform your doctor about all other medications you are taking, including prescription, non-prescription, vitamins, and herbal supplements, as they may interact with BUTRUM 1MG INJ. Concurrent use with other central nervous system depressants like barbiturates, antihistamines, and tranquilizers can increase depressant effects. Nasal decongestants like oxymetazoline can slow its action, and azole antifungals like ketoconazole can affect its removal from the body. Combining it with other opioid pain relievers can lead to increased side effects such as drowsiness and breathing problems.

What precautions should be taken with BUTRUM 1MG INJ?

BUTRUM 1MG INJ can cause dizziness and drowsiness, so it is not recommended to drive or operate heavy machinery after receiving it until your alertness returns to normal. Alcohol consumption should be avoided as it can worsen these sedative effects. Patients with a history of stomach ulcers, heart disease, high blood pressure, lung problems (such as respiratory depression or severe bronchial asthma), gastrointestinal obstruction, or liver and kidney diseases should inform their doctor before receiving this medication. It is not recommended for individuals under 18 years of age. Butorphanol can be habit-forming, and sudden cessation can lead to withdrawal symptoms.

What happens if a dose of BUTRUM 1MG INJ is missed?

Since BUTRUM 1MG INJ is typically administered by a healthcare professional, missing a dose is unlikely. If a dose is missed when instructed to use at home, it's important to consult your doctor for guidance. Do not double the dose to make up for a missed one.

How should BUTRUM 1MG INJ be stored?

BUTRUM 1MG INJ should be stored in a cool and dry place, away from sunlight, excess moisture, heat, and out of reach of children. Discard any outdated medication. It is generally stored at 10ºC to 25ºC or below 30ºC.