Conflu 150mg Cap

CONFLU 150MG CAP

CONFLU 150MG CAP is an antifungal medication manufactured by EAST INDIA PHARMACEUTICAL WORKS LIMITED, primarily used to treat and prevent various fungal and yeast infections.

• Name

  • Brand Name: Conflu 150mg Capsule
  • Common Name: Fluconazole 150mg Capsule

• Composition

  • Active Ingredient: Fluconazole 150 mg

• Uses CONFLU 150MG CAP is prescribed for the treatment of a broad spectrum of fungal infections by inhibiting the growth of fungi. These include:

  • Systemic Fungal Infections: Such as systemic candidiasis (affecting blood, brain, heart, eyes, or other parts of the body), cryptococcal meningitis (fungal infection in the brain and spinal cord), and Coccidioidomycosis (a lung disease).
  • Mucosal Candidiasis: Including oral thrush (mouth and throat infections), esophageal candidiasis, and denture sore mouth.
  • Vaginal Candidiasis: Fungal infection of the vagina and associated candidal balanitis in men.
  • Skin and Nail Infections: Such as ringworm, athlete's foot, jock itch, tinea corporis, tinea cruris, tinea capitis, onychomycosis (fingernails and toenails), and pityriasis versicolor.
  • Urinary Tract Infections (UTIs): Caused by Candida.
  • Prophylaxis: To prevent fungal infections in immunocompromised patients, such as those with HIV/AIDS, cancer patients undergoing chemotherapy or radiation therapy, or bone marrow transplant recipients.

• Dosage and Administration CONFLU 150MG CAP should be taken in the dose and duration as advised by a doctor.

  • It is typically swallowed whole with a glass of water.
  • Can be taken with or without food, but taking it at a fixed time is recommended. Some sources suggest taking it after food to avoid stomach upset.
  • The dosage and length of treatment depend on the condition being treated, age, body weight, and type of infection.
  • It is crucial to complete the full course of treatment even if symptoms improve to ensure complete eradication of the infection and prevent recurrence.

• Side Effects Common side effects include:

  • Headache
  • Nausea and Vomiting
  • Abdominal pain/Stomach discomfort
  • Diarrhea
  • Skin rash
  • Indigestion, heartburn
  • Dizziness
  • Hair loss (rare)

  Serious side effects that require immediate medical attention:

  • Signs of allergic reaction (rash, swelling of face/lips/tongue/throat, difficulty breathing).
  • Signs of liver problems (tiredness, loss of appetite, vomiting, yellowing of skin or whites of eyes, dark urine).
  • Severe skin reactions like Stevens-Johnson Syndrome or Epidermal Necrolysis (painful rashes, blistering, peeling skin).
  • Irregular or fast heart rate, palpitations, seizures, or fainting (indicating QT prolongation or Torsades de Pointes).

• Precautions

  • Pregnancy: CONFLU 150MG CAP is generally unsafe during pregnancy and may increase the risk of miscarriage or cause severe birth defects with large doses. Use reliable contraception for at least one week after stopping the medicine.
  • Breastfeeding: Not recommended for breastfeeding mothers, especially with repeated use or high doses, as it passes into human milk.
  • Liver/Kidney/Heart Conditions: Use with caution in patients with liver, kidney, or heart problems, including those with heart rhythm problems or QT prolongation.
  • Allergies: Do not take if allergic to Fluconazole or other ingredients.
  • Driving/Operating Machinery: May cause dizziness or fits; avoid these activities if affected.
  • Drug Interactions: Inform your doctor about all medicines, vitamins, and herbal supplements, as Fluconazole can interact with blood thinners (e.g., warfarin), antidiabetic medications, cyclosporine, phenytoin, theophylline, rifabutin, sulfonylureas, and certain antiviral drugs. Co-administration with terfenadine or cisapride is contraindicated due to increased risk of cardiotoxicity.
  • Alcohol: Caution is advised when consuming alcohol.

• Storage

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of sight and reach of children.
  • Do not store above 25°C or below 30°C in cool places. Protect from light and moisture.
  • Store at controlled room temperature (30°C) in an airtight container.

CONFLU 150MG CAP contains Fluconazole 150mg, an antifungal medication manufactured by East India Pharmaceutical Works Limited. Here are some frequently asked questions about this medicine:

What is CONFLU 150MG CAP used for?

CONFLU 150MG CAP (Fluconazole) is an antifungal medicine primarily used to treat various fungal and yeast infections. This includes vaginal yeast infections (thrush), oral thrush (in the mouth and throat), esophageal candidiasis, and systemic candidiasis (infections in the blood, urinary tract, lungs, and other organs). It is also used for skin infections like ringworm, athlete's foot, and nail fungus, as well as cryptococcal meningitis. In some cases, it may be prescribed to prevent fungal infections in high-risk individuals.

How does CONFLU 150MG CAP work?

CONFLU 150MG CAP works by stopping the growth of fungi. It belongs to a class of drugs called triazole antifungals. Its active ingredient, fluconazole, inhibits an enzyme essential for the production of ergosterol, a vital component of the fungal cell membrane. By disrupting the cell membrane's formation, it either kills the fungi or prevents them from growing and spreading.

What is the usual dosage of CONFLU 150MG CAP?

The dosage of CONFLU 150MG CAP varies depending on the type and severity of the infection. For vaginal yeast infections, a single 150 mg dose is often prescribed. For recurrent vaginal thrush, a regimen of 150 mg every 72 hours for three doses, followed by 150 mg once weekly for six months, might be recommended. Other fungal infections may require daily doses ranging from 50 mg to 400 mg for several weeks or months. Always follow your doctor's specific instructions regarding dosage and duration.

What are the possible side effects of CONFLU 150MG CAP?

Common side effects can include headache, stomach discomfort or pain, nausea, vomiting, diarrhea, dizziness, rash, and altered food taste. Less common but more serious side effects may include severe skin reactions (such as blistering or peeling skin, or DRESS syndrome), liver problems (indicated by yellowing of the skin or eyes, fatigue, loss of appetite, dark urine, or pale stools), irregular heartbeat or QT prolongation, adrenal gland problems, or severe allergic reactions (e.g., swelling of the face, lips, tongue, or difficulty breathing). If you experience any severe or persistent side effects, contact your doctor immediately.

Is CONFLU 150MG CAP safe during pregnancy or breastfeeding?

Pregnancy: CONFLU 150MG CAP is generally not recommended during pregnancy unless specifically advised by a doctor, particularly in the first trimester, due to potential risks. High doses (400-800 mg daily for extended periods) have been associated with birth defects. A single 150 mg dose for vaginal yeast infections is considered unlikely to significantly increase the risk of birth defects. It is important to use effective birth control during treatment and for at least one week after the last dose if you are of childbearing potential.

Breastfeeding: A single 150 mg dose of fluconazole is generally considered safe while breastfeeding, as the amount that passes into breast milk is usually small and unlikely to harm the infant. However, if you are taking repeated doses, or if your baby develops symptoms like stomach upset or diarrhea, consult your doctor. If your baby has oral thrush, they will need their own specific treatment as the amount in breast milk is not sufficient to treat the infant's infection.

Can CONFLU 150MG CAP be taken with other medications?

CONFLU 150MG CAP (fluconazole) can interact with many other medications, some of which are contraindicated (should not be taken together). Examples of drugs that should not be taken with fluconazole include terfenadine, astemizole, cisapride, pimozide, quinidine, and erythromycin. Caution and dose adjustments may be necessary with blood thinners (like warfarin), certain antidiabetic medications (like glipizide), some antibiotics (like rifampicin), benzodiazepines, phenytoin, cyclosporine, statins, and certain antidepressants. Always inform your doctor or pharmacist about all other medications, vitamins, and herbal supplements you are taking to avoid potential interactions.

What precautions should be taken while using CONFLU 150MG CAP?

Before taking CONFLU 150MG CAP, inform your doctor about any pre-existing medical conditions, especially liver disease, kidney disease, or heart conditions (particularly heart rhythm disorders or QT prolongation). Also, disclose any history of allergic reactions to fluconazole or other antifungal medicines. Avoid or limit alcohol consumption while on this medication, and avoid grapefruit or grapefruit juice, as these can increase the risk of side effects. If you develop a severe skin rash, signs of liver problems (e.g., jaundice, persistent nausea), or symptoms of adrenal problems (e.g., unusual tiredness, muscle weakness), stop the medication and seek immediate medical attention.

What happens if a dose of CONFLU 150MG CAP is missed?

If you miss a dose of CONFLU 150MG CAP, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this could increase the risk of side effects.

How should CONFLU 150MG CAP be stored?

CONFLU 150MG CAP should be stored in a cool, dry place, typically below 30°C (86°F), away from direct light and moisture. Keep the medication out of the reach and sight of children. Do not store it in the bathroom or near a sink, as heat and dampness can degrade medicines.