Hyperneb 7% Respules

HYPERNEB 7% RESPULES by CIPLA LTD.

HYPERNEB 7% RESPULES is a sterile hypertonic saline solution designed for inhalation therapy, manufactured by Cipla Ltd. It is used to improve respiratory health by assisting in the management of various respiratory conditions.

Composition

The active ingredient in HYPERNEB 7% RESPULES is Sodium Chloride (7% w/v). It also contains Water for Injections IP.

Uses

HYPERNEB 7% RESPULES is primarily used to support respiratory health and manage conditions characterized by thick mucus in the lungs. Its key uses include:

• Mucus Clearance: Helps break down and thin thick mucus in the airways, making it easier to expel and improving lung function.
• Airway Hydration: Keeps the airways moist, preventing dryness and facilitating smoother air passage.
• Relief from Congestion: Effectively relieves nasal and chest congestion, providing comfort to individuals with respiratory ailments.
• Management of Infections: By clearing mucus, it may help reduce the risk of bacterial and viral infections in the respiratory tract.
• Improves Medication Delivery: Prepares the airways to absorb other inhaled medications more effectively, enhancing their efficacy.

It is widely used in the management of respiratory conditions such as Chronic Obstructive Pulmonary Disease (COPD), asthma, and bronchitis.

Dosage and Administration

HYPERNEB 7% RESPULES is for inhalation only and must be used with a nebulizer, strictly under the direction of a physician. It should not be injected or administered orally.

To use:

1. Remove a single respule from the combipack.
2. Twist off the top of the respule.
3. Squeeze the entire content into the reservoir of the nebulizing chamber.
4. Inhale the solution via the nebulizer as advised by the physician.
5. Discard the respule immediately after use, as each respule is for single-use only.
6. Discard any unused solution remaining in the nebulizer.

The dosage and frequency should be as prescribed by a healthcare professional.

Side Effects

HYPERNEB 7% RESPULES is generally considered safe and well-tolerated.

• Common (mild): Mild throat irritation or coughing may occur initially, but usually subsides. Other rare mild side effects include runny nose, sneezing, irritability, skin rash, and fever.
• Serious: If any persistent or concerning side effects occur, such as increased irritation or difficulty breathing, discontinue use and consult a doctor.

Precautions

• Do not exceed the recommended dosage.
• Consult a healthcare professional if any adverse reactions occur, or if you are pregnant, lactating, or have any existing medical conditions. Pregnant women should consult their healthcare provider before use to ensure it is appropriate for their condition.
• Use with caution in children and elderly patients, and consult a doctor for specific guidance.
• If you have a tendency to develop dyspnoea (difficult or labored breathing), HYPERNEB 7% RESPULES should be used with medical supervision.
• It is generally not recommended to mix different medications in the same nebulizer without proper guidance from a healthcare professional.
• Not advised to inhale HYPERNEB 7% RESPULES immediately after using other inhaled medications that need to remain in the airways for effective functioning (e.g., inhaled corticosteroids, nebulized antibiotics, dornase alpha), as it causes increased pulmonary clearance.
• Individuals on a restricted sodium diet due to high blood pressure should consult their doctor for specific guidance.

Storage

Store HYPERNEB 7% RESPULES below 30°C. Keep in a cool, dry place, away from direct sunlight. Keep out of sight and reach of children. Do not use the product after its expiry date.

HYPERNEB 7% RESPULES is a sterile hypertonic saline solution used for inhalation therapy. It contains 7.00%w/v Sodium Chloride.

What is HYPERNEB 7% RESPULES used for?

HYPERNEB 7% RESPULES is primarily used to relieve respiratory congestion, thin and loosen mucus, and aid in airway clearance. It is commonly prescribed for individuals with conditions such as cystic fibrosis, bronchiectasis, asthma, and chronic obstructive pulmonary disease (COPD) to help improve breathing and reduce lung infections.

How does HYPERNEB 7% RESPULES work?

This medicine is a sodium chloride (salt) solution. When inhaled through a nebulizer, it works by drawing water into the airways via osmosis. This process rehydrates the mucus layer, making thick, sticky phlegm thinner and easier to cough up and clear from the lungs. It may also stimulate a cough, further assisting in mucus removal.

What is the usual dosage for HYPERNEB 7% RESPULES?

The usual dose is typically 4ml, administered once or twice daily, using a nebulizer. Your doctor or physiotherapist will provide specific instructions based on your condition.

What are the possible side effects of HYPERNEB 7% RESPULES?

Common side effects can include chest tightness, wheeze, cough, and a sore throat or throat irritation. These symptoms often lessen with continued use as your airways adjust to the treatment. If you experience severe or persistent side effects, stop using the medication and contact your doctor or physiotherapist.

Is HYPERNEB 7% RESPULES safe during pregnancy or breastfeeding?

Hypertonic saline is generally considered safe during pregnancy and breastfeeding. Maintaining good control of your respiratory condition during pregnancy is important, and this treatment can help. It is safe to breastfeed while taking this treatment.

Can HYPERNEB 7% RESPULES be taken with other medications?

HYPERNEB 7% RESPULES generally does not interact with other medications you may be taking. However, it should be administered after any nebulized or inhaled bronchodilators (such as salbutamol or bricanyl) and before or during chest physiotherapy. If you are also prescribed nebulized antibiotics, take your hypertonic saline before taking the antibiotics. Do not mix HYPERNEB 7% RESPULES with other medications in the same nebulizer.

What precautions should be taken when using HYPERNEB 7% RESPULES?

HYPERNEB 7% RESPULES should only be used through a nebulizer, and using a mouthpiece is often recommended over a mask if possible. If you are prone to chest tightness or wheezing, your doctor may advise you to use a bronchodilator (like salbutamol) about 10-15 minutes before your hypertonic saline treatment to help prevent bronchospasm. Individuals with heart failure, kidney problems, or high blood pressure should use this medication cautiously and consult their doctor for specific guidance.

What happens if a dose of HYPERNEB 7% RESPULES is missed?

If you miss a dose, do not worry. Take your next dose as scheduled. The chance of your chest condition worsening due to one missed dose is very small.

How should HYPERNEB 7% RESPULES be stored?

HYPERNEB 7% RESPULES should be stored in a cool, dry place at room temperature, away from extreme cold or heat. Ensure that the vials are not opened or damaged before use. After a vial has been opened, discard any unused saline. Keep all medications out of reach of children.