Zita Dm Tablet

ZITA DM TABLET

ZITA DM Tablet is a combination medication developed by GLENMARK-DIABETES CARE DIV, prescribed for the management of Type 2 Diabetes Mellitus. It works to improve blood sugar control through multiple mechanisms of action, assisting in the proper utilization of insulin and reducing overall blood glucose levels.

Composition ZITA DM Tablet contains a combination of three active ingredients:

• Dapagliflozin: A sodium-glucose cotransporter-2 (SGLT2) inhibitor that helps remove excess sugar from the body via urine.
• Teneligliptin: A dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations.
• Metformin: A biguanide that works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin.

The specific strengths of these components may vary depending on the tablet formulation (e.g., 10mg Dapagliflozin, 20mg Teneligliptin, and 500mg or 1000mg Metformin).

Uses ZITA DM Tablet is used for:

• Management of Type 2 Diabetes Mellitus.
• Lowering blood glucose levels.
• Improving insulin sensitivity.
• Reducing the risk of diabetes-related complications.
• Enhancing overall glycemic control.

Dosage and Administration This medicine should be taken orally as a whole tablet with a glass of water, typically with food or as directed by a healthcare provider. Do not crush, break, or chew the tablet. The exact dose and duration will be determined by your doctor, and it should not be discontinued abruptly without medical advice.

Side Effects Common side effects may include:

• Vomiting, nausea, abdominal pain.
• Headache, dizziness, drowsiness.
• Frequent urination, urinary tract infection (UTI).
• Vaginal yeast infection (in females) and genital fungal infections (in males).
• Diarrhea, constipation.
• Hypoglycemia (low blood sugar), especially when combined with other antidiabetic medications.
• Allergic reactions.

More serious but less common side effects can include lactic acidosis (especially with alcohol consumption) and acute pancreatitis (with prolonged intake).

Precautions

• Allergies: Avoid if allergic to any of the active ingredients or excipients.
• Medical Conditions: Inform your doctor if you have kidney or liver problems, heart conditions, hypertension, a history of urinary tract infections, gallstones, or pancreatitis.
• Pregnancy and Breastfeeding: Generally not recommended. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Alcohol Consumption: Avoid or limit alcohol intake as it can increase the risk of hypoglycemia and lactic acidosis.
• Driving and Operating Machinery: This medicine may cause dizziness or drowsiness, so exercise caution when driving or operating machinery until you know how it affects you.
• Dehydration: Dapagliflozin can increase urine output, potentially leading to dehydration. Ensure adequate fluid intake.
• Pediatric Use: Not recommended for use in children below 18 years of age due to a lack of established safety and efficacy data.
• Drug Interactions: Inform your doctor about all other medications, including over-the-counter drugs, herbal remedies, and supplements, to avoid potential drug interactions.

Storage Store ZITA DM Tablet in a cool, dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children. The medicine should be stored at temperatures between 10ºC to 25ºC or below 30ºC.

ZITA DM Tablet, manufactured by Glenmark-Diabetes Care Div, is a combination medication used to manage Type 2 Diabetes Mellitus. It contains three active ingredients: Dapagliflozin, Teneligliptin, and Metformin.

Here are some frequently asked questions about ZITA DM Tablet:

What is ZITA DM Tablet used for?

ZITA DM Tablet is an antidiabetic medicine primarily used to treat Type 2 Diabetes Mellitus in adults. It works to help control high blood sugar levels, reducing the risk of serious complications such as kidney damage, eye damage, nerve problems, and loss of limbs.

How does ZITA DM Tablet work?

ZITA DM Tablet is a combination of three different medications that work in synergistic ways:

• Dapagliflozin helps remove excess sugar from the body through urine.
• Teneligliptin works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels.
• Metformin helps lower glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin.

What is the usual dosage for ZITA DM Tablet?

The dosage and duration of ZITA DM Tablet should be precisely as advised by your doctor. It should be taken with food, swallowed whole, and not crushed, broken, or chewed. Do not stop taking it without consulting your doctor.

What are the possible side effects of ZITA DM Tablet?

Common side effects may include vomiting, nausea, abdominal pain, headache, frequent urination, and allergic reactions. Other possible side effects include vaginal yeast infection, nasopharyngitis (inflammation of the throat and nasal passages), and urinary tract infections. Low blood sugar (hypoglycemia) can occur, especially if taken with other antidiabetic medicines, alcohol, or if a meal is missed. There is also a rare but serious risk of lactic acidosis due to metformin accumulation, which increases with liver or kidney insufficiency and alcohol consumption.

Is ZITA DM Tablet safe during pregnancy or breastfeeding?

ZITA DM Tablet is generally not recommended and should be avoided during pregnancy. Animal studies have shown harmful effects on the developing baby, and your doctor will weigh the benefits against potential risks before prescribing it. During breastfeeding, ZITA DM Tablet is probably unsafe to use as limited human data suggest the drug may pass into breast milk and harm the baby. Doctor consultation is advised.

Can ZITA DM Tablet be taken with other medications?

ZITA DM Tablet can interact with various medications. It is crucial to inform your doctor about all medicines, including over-the-counter drugs, herbal products, and supplements you are currently taking. Interactions can occur with diuretics (water pills), insulin, insulin secretagogues (like glipizide or glimepiride), certain blood pressure medicines, antidepressants, and painkillers.

What precautions should be taken while taking ZITA DM Tablet?

Several precautions should be observed:

• Alcohol Consumption: Avoid drinking alcohol as it increases the risk of hypoglycemia (low blood sugar) and lactic acidosis.
• Pre-existing Conditions: Inform your doctor if you have kidney or liver problems, heart conditions, hypertension, urinary tract infections, or a history of pancreatitis.
• Children: This medicine is not recommended for use in children below 18 years of age as its safety and effectiveness have not been established.
• Driving and Operating Machinery: Your ability to drive or operate machinery may be affected if your blood sugar is too low or too high, leading to dizziness or drowsiness. Exercise caution until you know how the medication affects you.
• Hydration and Hygiene: Drink plenty of fluids to prevent dehydration, especially since dapagliflozin increases urine output. Maintaining good hygiene can also help prevent genital fungal infections.
• Lifestyle: This medication should be used as part of a comprehensive treatment plan that includes a healthy diet and regular exercise.

What happens if a dose of ZITA DM Tablet is missed?

If you miss a dose of ZITA DM Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should ZITA DM Tablet be stored?

ZITA DM Tablet should be stored in a cool and dry place, away from direct sunlight, ideally below 30°C. Keep the medication out of the sight and reach of children, and protect it from moisture and light.