Maxiliv Inj

MAXILIV INJ by ZUVENTUS GROMAXX

Name

Brand Name: Maxiliv Injection Common Name: Glutathione for Injection

Composition

Each vial of Maxiliv Injection contains Glutathione BP 600 mg. Glutathione is a physiological tripeptide composed of three amino acids: cysteine, glycine, and glutamic acid. It acts as a potent antioxidant.

Uses

Maxiliv Injection is prescribed for various liver-related conditions and as an antioxidant. It is indicated for:

• Alcoholic fatty liver
• Alcoholic liver fibrosis
• Alcoholic liver cirrhosis
• Alcoholic hepatitis
• Liver damage in HIV/HCV co-infection
• Gastritis
• As an add-on to the standard of care in moderate COVID-19 patients
• General antioxidant support and managing glutathione deficiency in various liver disorders

Dosage and Administration

Maxiliv Injection is administered by a healthcare professional via slow intramuscular or intravenous injection or intravenous infusion; it should not be self-administered.

• For Liver Conditions (mild to moderate): 300 mg to 600 mg daily. It can be given slowly into a muscle or through a vein.
• For Intravenous Drip: Dissolve with 5 ml sterile water for injections, then dilute further into 250 ml or 500 ml with normal saline or 5% glucose solution.
• For Intramuscular Injection: Dissolve with 5 ml sterile water for injections and inject intramuscularly, preferably in the gluteal region.
• For Moderate COVID-19 Patients (as an add-on): A loading dose of 4 vials (600 mg x 4) followed by a maintenance dose of 2 vials (600 mg x 2) every 12 hourly as intravenous injection for a maximum of 7 days or until clinical improvement. The dosage and duration depend on the severity of the disease and individual factors.

Side Effects

Common side effects may include:

• Skin rash
• Pain, redness, and swelling at the injection site
• Flatulence
• Loose stools
• Flushing
• Weight gain
• Anorexia
• Nausea and vomiting Less common but serious side effects can include febrile reactions, infections, thrombosis, phlebitis, and extravasation. Consult a doctor if any side effects persist or worsen.

Precautions

• Maxiliv Injection is contraindicated in patients with hypersensitivity to reduced Glutathione.
• Administer under the supervision of a doctor. Do not self-administer.
• Use with caution in neonates, premature infants, children, adolescents, and elderly patients, who may require close monitoring or lower doses.
• Pregnant and breastfeeding women should only use this injection if the doctor determines the benefits outweigh the risks.
• Inform your doctor about any pre-existing conditions like asthma, liver, or kidney problems.
• Some vitamins (Vitamin K, B12, Calcium pantothenate) and allergy medicines (antihistamines) can affect the bioavailability of Glutathione. Inform your doctor about all medications, herbal products, and supplements being taken.
• Visually inspect the product for parenteral use before administration to detect particles or abnormal color. Do not use in case of turbidity or precipitates.
• Avoid injecting at the same site repeatedly.

Storage

Store below 25°C. Protect from light. Keep out of reach of children. After reconstitution, use immediately and do not use if any foreign particulate matter is observed inside the vial.

MAXILIV INJ, containing Glutathione, is an antioxidant medicine primarily used to support liver health. It is administered by a healthcare professional as an intramuscular or intravenous injection.

Here are some frequently asked questions about MAXILIV INJ:

What is MAXILIV INJ used for?

MAXILIV INJ is primarily used to treat various liver conditions, including alcoholic fatty liver, alcoholic liver fibrosis, alcoholic liver cirrhosis, and alcoholic hepatitis. It also addresses liver damage in HIV/HCV co-infection and gastritis. Additionally, it may be used as an add-on treatment for moderate COVID-19 patients and offers general antioxidant support. Some sources also mention its use for improving skin complexion.

How does MAXILIV INJ work?

MAXILIV INJ contains Glutathione, a powerful antioxidant. It works by directly neutralizing harmful free radicals and other reactive oxygen species, thereby protecting liver cells and other body cells from damage caused by harmful chemicals.

What is the usual dosage for MAXILIV INJ?

For liver conditions, the typical dosage is 300 mg to 600 mg once daily, administered by slow intramuscular or intravenous injection. For moderate COVID-19 patients, as an add-on to standard care, a loading dose of 4 vials (600 mg each) is followed by a maintenance dose of 2 vials (600 mg each) every 12 hours for a maximum of 7 days or until clinical improvement. MAXILIV INJ should always be administered by a doctor or nurse.

What are the possible side effects of MAXILIV INJ?

Common side effects include skin rash, pain, redness, and swelling at the injection site. Other reported side effects are flatulence, loose stools, flushing, weight gain, anorexia, nausea, and vomiting. More serious but less common side effects can include febrile reactions, infections at the injection site, venous thrombosis, phlebitis, or extravasation. If you experience unusual symptoms such as a pale face, low blood pressure, or difficulty breathing, seek immediate medical attention.

Is MAXILIV INJ safe during pregnancy or breastfeeding?

MAXILIV INJ is generally not recommended for use in pregnant or breastfeeding women unless the doctor determines that the potential benefits outweigh the risks. Moderate side effects have been reported during pregnancy and breastfeeding, so it is crucial to consult your doctor before use.

Can MAXILIV INJ be taken with other medications?

Certain medications and supplements can affect how well MAXILIV INJ works. These include Vitamin K, Vitamin B12, Calcium pantothenate, and antihistamines. Always inform your doctor about all prescription and over-the-counter medications, herbal products, and vitamin/mineral supplements you are currently taking to avoid potential interactions.

What precautions should be taken with MAXILIV INJ?

MAXILIV INJ should only be administered under the supervision of a doctor. It should be kept out of reach of children. If administered intramuscularly, avoid injecting at the same site repeatedly. Before use, the solution should be visually inspected for any particles or abnormal color, and it should not be used if turbidity or precipitates are observed. The injection should be used immediately after reconstitution. Caution is advised in neonates, premature infants, children, adolescents, and older adults, who may require lower doses and close monitoring. It is contraindicated in patients with known hypersensitivity to Glutathione. Inform your doctor if you have asthma, liver problems (like chronic hepatitis), or kidney problems (like acute renal failure).

What happens if a dose of MAXILIV INJ is missed?

If a dose of MAXILIV INJ is missed, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should MAXILIV INJ be stored?

MAXILIV INJ should be stored below 25°C and protected from light. Keep it out of the reach of children. After reconstitution, the solution should be used immediately.