Cyclopam Injection (30ml)

Name

• Common Name: Cyclopam Injection
• Brand Name: CYCLOPAM INJECTION (30ML) by INDOCO REMEDIES LTD

Composition

• Active Ingredient: Dicyclomine 10 mg/ml.

Uses Cyclopam Injection is an antispasmodic medication primarily used to relieve symptoms associated with various gastrointestinal conditions. It is prescribed for:

• Abdominal pain and cramps
• Irritable Bowel Syndrome (IBS), managing symptoms such as cramping, bloating, diarrhea, and constipation
• Functional bowel disorders
• Menstrual pain and cramps
• Severe colicky conditions (intestinal, renal, or biliary colic)

Dosage and Administration Cyclopam Injection is administered intramuscularly by a healthcare professional in a hospital or clinical setting. Self-administration is not recommended. The specific dose and duration of treatment are determined by the doctor based on the patient's age, body weight, and medical condition.

Side Effects

• Common Side Effects: Dry mouth, blurred vision, nausea, dizziness, weakness, nervousness, drowsiness, abdominal pain, confusion, and dry skin.
• Serious Side Effects (consult doctor immediately if experienced): Allergic reactions (hives, difficulty breathing, swelling of face/lips/tongue/throat), fast or slow heartbeats, palpitations, chest fluttering, agitation, hallucinations, unusual thoughts or behaviors, problems with memory or speech, balance or muscle movement issues, severe constipation, diarrhea, or worsening of bowel symptoms, difficulty swallowing, bruising, swelling, pain, dehydration, and decreased urination.

Precautions

• Driving and Machinery: May cause dizziness and drowsiness; avoid driving or operating machinery until you know how the medicine affects you.
• Alcohol: Avoid alcohol consumption as it can worsen drowsiness and dizziness.
• Medical Conditions: Inform your doctor if you have kidney, liver, lung, or heart problems, myasthenia gravis, ulcerative colitis (may worsen the condition or lead to toxic megacolon), glaucoma (contraindicated or caution), enlarged prostate, reflux esophagitis, or obstructive disorders of the gastrointestinal or urinary tract.
• Pregnancy and Breastfeeding: Consult your doctor before use if you are pregnant or breastfeeding.
• Children and Elderly: Not recommended for infants less than six months old. Use with caution in elderly patients (above 65 or 75 years of age).
• Drug Interactions: Inform your doctor about all other medications you are taking, as interactions may occur (e.g., with antihistamines, antipsychotics, tricyclic antidepressants, certain glaucoma medications).

Storage Store Cyclopam Injection in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it out of sight and reach of children. Store below 25°C or 30°C.

What is Cyclopam Injection used for?

Cyclopam Injection is primarily used to manage abdominal pain and discomfort, particularly cramps associated with irritable bowel syndrome (IBS), functional bowel disorders, and other gastrointestinal issues. It also helps relieve symptoms like bloating, stomach cramps, and menstrual pain. Additionally, it can be used for severe colicky conditions such as intestinal, renal, or biliary colic.

How does Cyclopam Injection work?

Cyclopam Injection contains Dicyclomine (also known as Dicycloverine), which is an antispasmodic medication. It works by relaxing the smooth muscles in the stomach and intestines. Dicyclomine achieves this by directly acting on the smooth muscles and by blocking acetylcholine, a chemical messenger responsible for muscle contractions in the digestive system, thereby reducing painful spasms and improving the movement of food.

What is the usual dosage of Cyclopam Injection?

Cyclopam Injection is administered intramuscularly (into the muscle) by a doctor or a trained healthcare professional in a clinical setting. The typical dosage may vary, but it's often 10 mg to 20 mg four times a day. The exact dose and duration are prescribed by your doctor based on factors like your age, body weight, the severity of your condition, and your response to treatment. It is usually used for only 1 or 2 days when oral medication cannot be taken.

What are the possible side effects of Cyclopam Injection?

Common side effects of Cyclopam Injection include dryness of mouth, blurred vision, nausea, dizziness, weakness, sleepiness, and nervousness. More severe, but less common, side effects can include allergic reactions (hives, difficulty breathing, swelling of face/lips/tongue/throat), fast or slow heartbeats, confusion, agitation, hallucinations, memory or speech problems, balance or muscle movement issues, severe constipation or diarrhea, and difficulty swallowing. If any side effects persist or worsen, it is important to consult your doctor.

Is Cyclopam Injection safe during pregnancy or breastfeeding?

Caution is advised when using Cyclopam Injection during pregnancy. Dicyclomine, one of the active ingredients, is classified as a Pregnancy Category B medication by the FDA, meaning animal studies haven't shown risk, but human studies are limited. It should only be used if advised by your doctor, who will weigh the benefits against potential risks to the developing baby.

Cyclopam Injection is generally not recommended for use by breastfeeding women. Dicyclomine may pass into breast milk and is generally not recommended due to potential effects on the baby. Always discuss with your doctor if you are breastfeeding before using this medicine.

Can it be taken with other medications?

Cyclopam Injection can interact with several medications. It's crucial to inform your doctor about all other medicines, supplements, or herbal products you are taking. Interactions can occur with:

• Antihistamines (e.g., loratadine, cetirizine, diphenhydramine)
• Antipsychotics (e.g., risperidone, haloperidol, phenothiazines like thioridazine)
• Tricyclic antidepressants (e.g., amitriptyline, nortriptyline)
• Antiglaucoma agents (e.g., timolol, betaxolol, bimatoprost, latanoprost)
• Medicines for irregular heartbeat (e.g., quinidine, digoxin)
• Benzodiazepines (e.g., alprazolam, lorazepam)
• Amantadine (used for Parkinson's disease)
• Loperamide
• Antacids

These interactions can potentially increase the risk of side effects like dry mouth, blurred vision, and urinary retention.

What precautions should be taken?

Several precautions should be taken:

• Medical Conditions: Inform your doctor if you have conditions such as glaucoma, myasthenia gravis, severe ulcerative colitis, obstructive uropathy (blocked urine flow), obstructive gastrointestinal tract disease, enlarged prostate, reflux esophagitis, liver or kidney problems, or heart conditions (like congestive heart failure, coronary heart disease, high blood pressure, or a history of cardiac surgery).
• Driving and Operating Machinery: Cyclopam Injection may cause dizziness, drowsiness, or blurred vision. Avoid driving or operating machinery until you know how the medication affects you.
• Alcohol: Avoid or limit alcohol consumption as it can increase the risk of certain side effects like drowsiness and stomach problems.
• Children and Elderly: It is not recommended for children under 18 years of age without medical supervision, and caution is advised in elderly patients (over 65 years) as they may be more susceptible to side effects.
• Heat Stroke: Be cautious if you are experiencing heat stroke or fever, as this medicine may cause decreased sweating.

What happens if a dose is missed?

If you miss a dose of Cyclopam Injection, administer it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to compensate for the missed one, and never increase your dosage without consulting your doctor.

How should it be stored?

Cyclopam Injection should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat. It should generally be stored below 30°C (or between 10ºC to 25ºC). Keep the medicine out of sight and reach of children. Ensure to check the expiry date before administration.