Stablon Tablet (10 Tab)

STABLON TABLET (10 TAB) by SERDIA PHARMACEUTICALS (INDIA) PVT. LTD.

Name

• Brand Name: Stablon Tablet
• Common Name: Tianeptine (as Tianeptine sodium)

Composition Each tablet contains Tianeptine sodium 12.5 mg as the active ingredient.

Uses Stablon Tablet is an antidepressant primarily prescribed for the treatment of depression in adults. This includes:

• Major depressive episodes
• Neurotic or reactive depression
• Anxio-depressive states, including those with psychosomatic manifestations like digestive problems
• Anxio-depressive states observed in alcoholics during withdrawal Tianeptine also exhibits anxiolytic (anti-anxiety) properties.

Dosage and Administration The recommended dosage is generally one 12.5 mg tablet, three times a day (morning, midday, and evening), taken at the beginning of main meals. For patients over 70 years of age or those with renal insufficiency, the dosage should be restricted to two tablets per day. Do not abruptly discontinue treatment; the dosage should be gradually reduced over a period of 7 to 14 days to minimize the risk of withdrawal reactions.

Side Effects Common side effects may include:

• Drowsiness, dizziness, headache, fatigue
• Dry mouth, nausea, constipation, abdominal pain, diarrhea
• Loss of appetite, insomnia, nightmares
• Palpitations, chest pain, muscle pain

Serious side effects can include suicidal thoughts or behaviors, especially at the start of treatment or after dosage changes. Severe withdrawal symptoms, similar to those of opioids (agitation, nausea, vomiting, tachycardia, hypertension, diarrhea, tremor, diaphoresis, severe anxiety, depression), can occur with abrupt discontinuation, particularly after prolonged use or high doses. Liver damage and respiratory depression (at very high doses) are also serious concerns.

Precautions

• Stablon Tablet is contraindicated in children and adolescents under 15 years of age and generally not recommended for those between 15 and 18 years due to an increased risk of suicidal tendencies.
• Consumption of alcohol should be avoided during treatment as it may increase side effects like drowsiness.
• Caution is advised for patients with liver diseases, kidney problems, a history of seizures, bipolar disorder, schizophrenia, diabetes, heart disease, or bleeding disorders.
• Not recommended during pregnancy and breastfeeding unless specifically advised by a doctor, due to potential risks to the fetus or infant.
• If general anesthesia is required, the anesthetist should be informed, and discontinuation 24-48 hours prior to surgery may be necessary.
• Due to the potential for drowsiness, patients should avoid driving or operating heavy machinery until they know how the medicine affects them.
• A washout period is necessary when switching between Tianeptine and MAO inhibitors.
• There is a risk of dependence and abuse, especially in individuals with a history of substance abuse, and careful monitoring is required. Overdose symptoms include hallucinations, difficulty breathing, irregular heartbeat, seizures, and loss of consciousness.

Storage Store Stablon Tablet at a temperature below 30°C, in a cool, dry place, away from direct light and heat. Keep out of the sight and reach of children and pets.

STABLON Tablet contains Tianeptine and is primarily used as an antidepressant. It is manufactured by Serdia Pharmaceuticals (India) Pvt. Ltd..

Here are some frequently asked questions about STABLON Tablet:

What is STABLON Tablet used for?

STABLON Tablet is used to treat major depressive episodes in adults. This includes neurotic and reactive depression, as well as anxio-depressive states, which can include those with psychosomatic manifestations like gastrointestinal complaints, or those experienced by alcoholics during the withdrawal stage.

How does STABLON Tablet work?

STABLON Tablet contains Tianeptine, an antidepressant that affects certain chemical messengers (such as serotonin and norepinephrine) in the brain. It helps to regulate mood and prevent depression by influencing the communication between brain cells and increasing serotonin release, which can improve mood, cognition, and memory. Tianeptine also modulates glutamatergic neurotransmission.

What is the usual dosage for STABLON Tablet?

The recommended dosage for adults is one 12.5 mg tablet, three times a day (morning, midday, and evening), taken at the beginning of main meals. In elderly patients over 70 years old or those with severe renal impairment (kidney disease), the dosage may be restricted to two tablets per day. Always follow your doctor's specific instructions for dosage and administration.

What are the possible side effects of STABLON Tablet?

Common side effects may include increased heart rate, dry mouth, blurred vision, difficulty in urination, weight gain, constipation, and orthostatic hypotension (a sudden drop in blood pressure upon standing). Other reported side effects include drowsiness, dizziness, fatigue, headache, insomnia, nightmares, nausea, abdominal pain, muscle pain, and loss of appetite. In some cases, STABLON Tablet may also cause suicidal thoughts, so patients should be monitored closely.

Is STABLON Tablet safe during pregnancy or breastfeeding?

STABLON Tablet is generally not recommended for use during pregnancy, as animal studies have shown harmful effects on the developing baby, and there is limited human data available. It is also not recommended during breastfeeding, as the drug may pass into breast milk and potentially harm the baby. It is crucial to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can STABLON Tablet be taken with other medications?

STABLON Tablet should not be taken with irreversible Monoamine Oxidase Inhibitors (MAOIs) due to the risk of severe and potentially life-threatening side effects, including cardiovascular collapse or hyperthermia. A washout period of two weeks is required when replacing MAOIs with tianeptine, and 24 hours when replacing tianeptine with an MAOI. Caution is also advised when taken with other antidepressants, antipsychotics, antihypertensives, antibiotics, and any medications that may cause central nervous system (CNS) depression. Always inform your doctor about all other medicines, supplements, or herbal products you are taking.

What precautions should be taken while using STABLON Tablet?

You should avoid consuming alcohol while taking STABLON Tablet, as it can increase side effects like drowsiness. This medicine may cause drowsiness or dizziness, so it is advisable to avoid driving or operating heavy machinery until you understand how it affects you. Do not stop taking STABLON Tablet abruptly; the dosage should be gradually reduced over 7 to 14 days under medical supervision to avoid withdrawal symptoms. Patients should be monitored for suicidal thoughts, particularly younger individuals. Exercise caution if you have kidney or liver disease, heart problems, diabetes, glaucoma, epilepsy (seizures), or a history of substance abuse. Inform your doctor if you are scheduled for surgery requiring general anesthesia, as the medication may need to be discontinued beforehand.

What happens if a dose of STABLON Tablet is missed?

If you miss a dose of STABLON Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects.

How should STABLON Tablet be stored?

STABLON Tablet should be stored at a temperature below 30°C (some sources specify below 25°C) in a cool, dry place. Keep it away from heat and direct light. Ensure it is stored out of the reach and sight of children and pets.