Gluvilda M + 500 Mg Tablet (15 Tab)

GLUVILDA M + 500 MG TABLET

GLUVILDA M + 500 MG TABLET, also known as Gluvilda M +500 Tablet SR, is a medication manufactured by Alkem Laboratories Ltd.

• Composition: Each tablet contains Vildagliptin 50 mg and Metformin Hydrochloride 500 mg.
• Uses: This medicine is prescribed for the management of Type 2 diabetes mellitus in adults. It helps control high blood sugar levels and works to prevent serious diabetes-related complications such as kidney damage, blindness, heart attacks, and strokes.
• Dosage and Administration: GLUVILDA M + 500 MG TABLET should be taken orally with food, typically at the same time each day, as advised by your doctor. It should be swallowed whole; do not chew, crush, or break the tablet. The dosage is individualized based on the patient's condition, blood sugar levels, and other medications being taken.
• Side Effects: Common side effects may include nausea, headache, gastroesophageal reflux disease, diarrhea, vomiting, upset stomach, and sore throat. Hypoglycemia (low blood sugar) is also a possible side effect, especially when taken with other diabetes medications like insulin. A rare but serious side effect is lactic acidosis, which requires immediate medical attention.
• Precautions: GLUVILDA M + 500 MG TABLET is generally not recommended for use in patients with known allergies to its components, severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis. Caution is advised in patients with kidney, liver, or heart disease, pancreas problems, and those who consume alcohol. Alcohol consumption should be avoided as it can lower blood glucose and increase the risk of lactic acidosis. Pregnant or breastfeeding women should consult their doctor. Regular monitoring of kidney function and blood sugar levels is important during treatment.
• Storage: Store GLUVILDA M + 500 MG TABLET in its original container at room temperature, preferably below 30°C, away from direct sunlight and moisture. Keep it out of the sight and reach of children.

What is GLUVILDA M + 500 MG Tablet used for?

GLUVILDA M + 500 MG Tablet is used for the treatment of Type 2 diabetes mellitus in adults. It helps to control high blood sugar levels, which in turn helps prevent serious complications of diabetes such as kidney damage, blindness, nerve problems, and may also reduce the chances of having a heart attack or stroke. This medicine can be prescribed alone or along with other diabetes medications.

How does GLUVILDA M + 500 MG Tablet work?

GLUVILDA M + 500 MG Tablet is a combination of two anti-diabetic medicines: Metformin and Vildagliptin. Metformin, a biguanide, works by lowering the production of glucose in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin. Vildagliptin, a DPP-4 inhibitor, works by increasing the release of insulin from the pancreas (especially after meals) and decreasing the hormones (glucagon) that raise blood sugar levels. Together, these actions lead to better control of blood sugar.

What is the usual dosage for GLUVILDA M + 500 MG Tablet?

The dosage of GLUVILDA M + 500 MG Tablet should be taken exactly as advised by your doctor. It is typically taken with food to help reduce the chance of an upset stomach. You should swallow the tablet whole and not chew, crush, or break it. For the most benefit, it is important to take it regularly at the same time each day. Your doctor will determine the appropriate dose based on your condition, blood sugar levels, and any other medications you are taking.

What are the possible side effects of GLUVILDA M + 500 MG Tablet?

Common side effects may include nausea, headache, diarrhea, vomiting, upset stomach, sore throat, dizziness, and decreased appetite. Low blood sugar levels (hypoglycemia) can occur, especially if you are also taking other diabetes medicines like insulin or sulfonylurea; it is important to know how to recognize and manage these symptoms.

Rare but serious side effects can include:

• Lactic acidosis: A medical emergency characterized by muscle pain, weakness, dizziness, feeling cold in the limbs, difficulty breathing, persistent nausea, vomiting, or stomach pain.
• Pancreatitis: Inflammation of the pancreas, presenting as severe pain in the stomach, abdomen, or back, along with persistent nausea or vomiting and fever.
• Long-term use may also lead to Vitamin B12 deficiency.

Is GLUVILDA M + 500 MG Tablet safe during pregnancy or breastfeeding?

GLUVILDA M + 500 MG Tablet is generally not recommended for use during pregnancy, as there is limited safety data and the potential risk to humans is unknown. If you are pregnant or planning to become pregnant, consult your doctor for advice on safer alternatives.

Similarly, it is not recommended during breastfeeding. While metformin is known to pass into breast milk in low amounts, it is unknown if vildagliptin is excreted in human milk. Due to the potential risk of hypoglycemia in the newborn and lack of human data for vildagliptin, consult your doctor before breastfeeding while on this medication.

Can GLUVILDA M + 500 MG Tablet be taken with other medications?

GLUVILDA M + 500 MG Tablet can be used with other diabetes medications, but caution is advised, especially with insulin or sulfonylureas, as this can increase the risk of low blood sugar. Your doctor may adjust the dose of the sulfonylurea.

Vildagliptin generally has a low potential for drug interactions. However, certain medications can interact with GLUVILDA M + 500 MG Tablet. For example, there may be an increased risk of angioedema if taken with ACE inhibitors. Medications that can affect kidney function (like certain antihypertensives, diuretics, and NSAIDs) should be used with caution, as they might increase metformin exposure. Inform your doctor about all medications, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while taking GLUVILDA M + 500 MG Tablet?

It is crucial not to stop taking GLUVILDA M + 500 MG Tablet without consulting your doctor, as discontinuing it abruptly can cause blood sugar levels to rise. Always combine this medication with a healthy diet and regular exercise as recommended by your doctor.

Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis and pancreatitis. Inform your doctor if you have a history of kidney, liver, or heart disease, or problems with your pancreas, as regular monitoring of kidney and liver function will be necessary. Metformin should be temporarily discontinued before surgery involving general anesthesia or certain imaging scans (like X-rays using contrast dye). This medicine is not for Type 1 diabetes or diabetic ketoacidosis and is generally not recommended for individuals under 18 years of age.

What happens if a dose of GLUVILDA M + 500 MG Tablet is missed?

If you miss a dose of GLUVILDA M + 500 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should GLUVILDA M + 500 MG Tablet be stored?

Store GLUVILDA M + 500 MG Tablet in its original container, tightly closed, in a cool and dry place. Protect it from direct sunlight, moisture, and heat. The storage temperature should preferably be below 30°C. Keep this medicine out of the sight and reach of children and pets. Properly dispose of any unused or expired medication.