Pregalin D 75/20 Caps

PREGALIN D 75/20 CAPS

PREGALIN D 75/20 Capsule is a combination medicine manufactured by Torrent Pharmaceuticals Ltd (AXON) used for managing various types of nerve pain.

• Name:

  • Brand Name: PREGALIN D 75/20 CAPS

• Composition:

  • Each capsule contains Pregabalin 75 mg and Duloxetine 20 mg.

• Uses: PREGALIN D 75/20 is primarily prescribed for the treatment of neuropathic pain, which includes nerve pain caused by diabetes (diabetic neuropathy), shingles (post-herpetic neuralgia), and spinal cord injuries. It is also used to manage widespread musculoskeletal pain associated with fibromyalgia. Additionally, it may be used in the treatment of depression and anxiety disorders.

• Dosage and Administration: This medicine should be taken orally as directed by a doctor. It can be consumed with or without food, but it is advisable to take it at the same time each day to maintain a consistent level in the body. The capsule should be swallowed whole with water and not cut, broken, or chewed. Do not stop taking the medication abruptly, as it may cause withdrawal symptoms; the dosage should be gradually reduced under medical supervision.

• Side Effects: Common side effects may include headache, dizziness, drowsiness, difficulty sleeping, fatigue, nausea, diarrhea, dry mouth, blurred vision, loss of appetite, constipation, peripheral edema (swelling in the limbs), and weight gain. More serious side effects can include unusual mood changes or suicidal thoughts.

• Precautions: Inform your doctor if you have liver or kidney disease, heart conditions, diabetes, seizures, bipolar disorder, glaucoma, or bleeding disorders. It is not recommended for patients under 18 years of age. Alcohol consumption should be avoided as it can increase drowsiness and the risk of liver damage. Driving or operating heavy machinery should be avoided if the medicine causes dizziness, drowsiness, or blurred vision. Consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding. Interactions with other medications, especially blood thinners and certain antidepressants, should be discussed with a doctor.

• Storage: Store PREGALIN D 75/20 Capsules in dry conditions at room temperature, away from wet surfaces, direct sunlight, and humid conditions. Keep it out of reach of children and pets.

Here are the most frequently asked questions about PREGALIN D 75/20 CAPS:

What is PREGALIN D 75/20 CAPS used for?

PREGALIN D 75/20 CAPS is a combination medicine primarily used to treat neuropathic pain, which is pain caused by nerve damage or a malfunctioning nervous system. This includes nerve pain associated with diabetic neuropathy, postherpetic neuralgia (shingles), fibromyalgia, and spinal cord injuries. It can help alleviate symptoms such as burning, tingling, shooting, or stabbing pain, and also addresses widespread musculoskeletal pain in fibromyalgia.

How does PREGALIN D 75/20 CAPS work?

PREGALIN D 75/20 CAPS contains two active ingredients: Pregabalin and Duloxetine. Pregabalin works by binding to certain calcium channels in overactive nerve cells in the central nervous system, which reduces the release of neurotransmitters that transmit pain signals. Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that increases the levels of chemical messengers like serotonin and norepinephrine in the brain. These chemicals help modulate pain perception and improve mood, providing a dual approach to pain management and associated emotional well-being.

What is the usual dosage for PREGALIN D 75/20 CAPS?

PREGALIN D 75/20 CAPS contains 75mg of Pregabalin and 20mg of Duloxetine per capsule. The exact dosage and duration of treatment should always be as prescribed by your doctor. It is typically started at a lower dose and gradually increased to minimize side effects. Do not alter your dose or stop the medication without consulting your healthcare provider.

What are the possible side effects of PREGALIN D 75/20 CAPS?

Common side effects may include dizziness, sleepiness or drowsiness, headache, nausea, constipation, dry mouth, increased sweating, loss of appetite, fatigue, insomnia (difficulty sleeping), and a burning sensation. Other possible side effects include weight gain, blurred vision, fluid retention, uncoordinated body movements, ejaculation disorder, and erectile dysfunction. If these side effects persist or worsen, you should inform your doctor. More serious side effects, though less common, can include increased suicidal thoughts, increased blood pressure, and, rarely, seizures.

Is PREGALIN D 75/20 CAPS safe during pregnancy or breastfeeding?

PREGALIN D 75/20 CAPS is generally not recommended during pregnancy due to limited information on its effects on a developing baby. If you are pregnant or planning a pregnancy, it is crucial to discuss the risks and benefits with your doctor. Duloxetine and Pregabalin both pass into breast milk in small amounts. It is not fully known what effects these may have on a breastfed infant, so consult your doctor to determine the safest treatment option for you and your baby.

Can PREGALIN D 75/20 CAPS be taken with other medications?

You should inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions. Taking PREGALIN D 75/20 CAPS with alcohol or other central nervous system (CNS) depressants can increase drowsiness and dizziness. Combining it with other medications that affect serotonin levels (such as certain antidepressants) can increase the risk of a rare but serious condition called serotonin syndrome. It may also interact with drugs affecting liver enzymes or those that increase bleeding risk. Your blood pressure should be monitored regularly, especially during the first month of treatment.

What precautions should be taken while on PREGALIN D 75/20 CAPS?

Do not stop taking PREGALIN D 75/20 CAPS suddenly without your doctor's advice, as this can lead to withdrawal symptoms such as dizziness, tingling sensations, sleep disturbances, restlessness, nausea, vomiting, headache, or excessive sweating. Since this medication can cause drowsiness and dizziness, avoid driving or operating heavy machinery until you know how it affects you. Inform your doctor if you have any liver or kidney disease, seizures, mania, bipolar disorder, or glaucoma, as these conditions may require dose adjustments or careful monitoring.

What happens if a dose of PREGALIN D 75/20 CAPS is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Try to take your medicine at the same time each day to maintain consistent levels in your body.

How should PREGALIN D 75/20 CAPS be stored?

Store PREGALIN D 75/20 CAPS in dry conditions at room temperature, away from direct sunlight, moisture, and humid conditions. Keep the medicine in its original container and out of the reach of children and pets.