Perampa 4 Mg Tablet (10 Tab)

PERAMPA 4 MG TABLET

PERAMPA 4 MG TABLET by INTAS PHARMACEUTICALS LTD. is an antiepileptic medication used to manage seizures in patients with epilepsy.

Name

• Common Name: Perampa 4 MG Tablet
• Brand Name: Perampa
• Manufacturer: Intas Pharmaceuticals Ltd.

Composition

• Active Ingredient: Perampanel 4 mg

Uses Perampa 4 MG Tablet is primarily prescribed for the treatment of epilepsy, a neurological disorder characterized by recurrent seizures. It is used to manage:

• Partial-onset seizures, with or without secondary generalization, in patients aged 4 years and older.
• Generalized tonic-clonic seizures in patients aged 7 years and older.
• It can be used as an adjunctive therapy (in combination with other antiepileptic medicines) to help reduce the frequency and severity of seizures.

Dosage and Administration

• Take PERAMPA 4 MG TABLET exactly as prescribed by your doctor.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• It can be taken with or without food, but it is advised to take it at the same time each day, preferably at bedtime.
• Do not stop taking this medicine suddenly without consulting your doctor, as it may increase seizure frequency and lead to withdrawal symptoms.

Side Effects Common Side Effects:

• Dizziness
• Drowsiness (somnolence)
• Increased or decreased appetite, weight gain
• Aggression, anger, irritability, anxiety, or confusion
• Difficulty walking, balance disorder, gait disturbance (ataxia)
• Slow speech (dysarthria)
• Blurred or double vision (diplopia)
• Spinning sensation (vertigo)
• Nausea, back pain, extreme fatigue Serious Side Effects (seek immediate medical attention if experienced):
• Severe skin reactions such as Stevens-Johnson syndrome (reddish target-like circular patches with central blisters, skin peeling, ulcers) or Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
• Psychiatric and behavioral changes, including aggression, hostility, irritability, anger, and suicidal thoughts.

Precautions

• Allergies: Do not take if you are allergic to perampanel or any other ingredients in the tablet.
• Liver/Kidney Impairment: Not recommended for patients with serious liver problems or moderate to severe kidney issues. Use with caution in mild to moderate liver or kidney impairment.
• Alcohol and Driving: Avoid consuming alcohol as it can increase dizziness and drowsiness. Do not drive or operate heavy machinery until you know how the medicine affects you.
• Pregnancy and Breastfeeding: Consult your doctor before use if you are pregnant, planning a pregnancy, or breastfeeding, as it may be unsafe.
• Substance Abuse History: Use with caution in patients with a history of alcoholism or drug dependence due to potential for abuse.
• Drug Interactions: Inform your doctor about all other medications you are taking, especially other antiepileptics (e.g., carbamazepine, phenytoin), sedatives (e.g., diazepam, alprazolam), and antidepressants (e.g., fluoxetine, sertraline), as interactions may occur.

Storage

• Store PERAMPA 4 MG TABLET below 30°C.
• Keep the medicine in a closed container, away from heat, moisture, and direct light.
• Keep out of the reach of children.

What is Perampa 4 MG Tablet used for?

Perampa 4 MG Tablet is an antiepileptic medication primarily used to treat epilepsy and control seizures. It is prescribed for partial-onset seizures, with or without secondary generalized seizures, and for primary generalized tonic-clonic seizures in adults and children aged 4-12 years and older. It can be used as an add-on therapy with other antiepileptic drugs.

How does Perampa 4 MG Tablet work?

Perampa 4 MG Tablet contains perampanel as its active ingredient. It works by blocking specific glutamate receptors in the brain, known as AMPA receptors. By inhibiting these receptors, it helps to reduce the abnormal and excessive electrical activity of nerve cells in the brain, which is responsible for triggering seizures.

What is the usual dosage for Perampa 4 MG Tablet?

The typical starting dose for adults and children (4 years and older for partial-onset seizures, 7 years and older for generalized seizures) is 2 mg once daily, usually taken at bedtime. Your doctor may gradually increase the dose based on your response and tolerability. The dose should not exceed 12 mg per day. Always follow your doctor's instructions precisely.

How should Perampa 4 MG Tablet be taken?

Swallow the tablet whole with a glass of water. Do not chew, crush, or break it. It can be taken with or without food, but it is best to take it at the same time each day to maintain consistent levels of the medicine in your body.

What are the possible side effects of Perampa 4 MG Tablet?

Common side effects include dizziness, drowsiness, fatigue, changes in appetite (increased or decreased), weight gain, and feelings of aggression, anger, irritability, anxiety, or confusion. Other possible side effects include difficulty with walking or balance, slow speech, blurred or double vision, vertigo (spinning sensation), nausea, and back pain. More serious side effects can include severe psychiatric and behavioral reactions, and in rare cases, suicidal thoughts. If you experience any persistent or concerning side effects, especially mood changes, contact your doctor.

Is Perampa 4 MG Tablet safe during pregnancy or breastfeeding?

Perampa 4 MG Tablet is generally not recommended during pregnancy as animal studies suggest potential harm to the developing baby. For breastfeeding mothers, it is likely unsafe to use as the medication may pass into breast milk and affect the baby. Women of child-bearing potential should use reliable contraception while taking this medicine and for one month after stopping it. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can Perampa 4 MG Tablet be taken with other medications?

Perampa 4 MG Tablet can interact with other medications. It's important to inform your doctor about all medicines you are taking, including over-the-counter drugs, herbal remedies, and supplements. Some anti-epileptic medications (e.g., carbamazepine, oxcarbazepine, phenytoin) may affect Perampa tablet. It can also reduce the effectiveness of hormonal contraceptives, such as those containing levonorgestrel, requiring the use of alternative birth control methods. Alcohol and cannabis can increase central nervous system (CNS) depression and other side effects when taken with Perampa.

What precautions should be taken while on Perampa 4 MG Tablet?

Avoid consuming alcohol while taking Perampa 4 MG Tablet, as it can worsen side effects like dizziness and drowsiness, and may increase the risk of seizures. Do not drive or operate heavy machinery until you know how this medicine affects you, as it can cause dizziness and sleepiness. Inform your doctor if you have kidney or liver problems, a history of substance abuse, depression, or suicidal thoughts. Do not suddenly stop taking the medication without consulting your doctor, as abrupt discontinuation can increase seizure frequency and lead to withdrawal symptoms.

What happens if a dose of Perampa 4 MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Missing doses can increase the risk of seizures.

How should Perampa 4 MG Tablet be stored?

Store Perampa 4 MG Tablet in a closed container at room temperature, away from heat, moisture, and direct light. Keep it out of the reach of children. Do not use outdated medicine.