Zenflox Plus 100 (10 Tab)

ZENFLOX PLUS 100 (10 TAB) by MANKIND PHARMA LTD

Zenflox Plus 100 Tablet is a broad-spectrum antibiotic medication manufactured by Mankind Pharmaceuticals Ltd., used to treat a variety of bacterial infections.

Composition Each tablet contains:

• Cefixime: 100 mg
• Ofloxacin: 100 mg

Uses Zenflox Plus 100 Tablet is prescribed for the management of various bacterial infections in adults, including:

• Typhoid Fever: Effective against Salmonella typhi bacteria.
• Respiratory Tract Infections: Such as community-acquired pneumonia, acute exacerbations of chronic bronchitis, pharyngitis, tonsillitis, and sinusitis.
• Urinary Tract Infections (UTIs): Including acute uncomplicated cystitis, pyelonephritis, and complicated UTIs.
• Gastrointestinal Infections: Including bacterial gastroenteritis, traveler's diarrhea, dysentery, and shigellosis.
• Sexually Transmitted Infections (STIs): Such as uncomplicated urethral, endocervical, or rectal infections, chlamydia, and gonorrhea.
• Skin and Soft Tissue Infections.
• Middle Ear Infections (Otitis Media).
• Prostate Infections.

Dosage and Administration Adhere to the following instructions when taking Zenflox Plus 100 Tablet:

• Swallow the tablet whole with a glass of water. Do not crush, break, or chew it.
• It can be taken with or without food, though taking it with food may help reduce gastrointestinal discomfort.
• Always take the medicine at regular intervals as advised by your doctor.
• Complete the full course of treatment as prescribed by your doctor, even if symptoms improve, to prevent the infection from returning or becoming resistant.
• Do not stop taking this medicine without your doctor's approval.

Side Effects Common side effects may include:

• Nausea, vomiting, diarrhea, loose stools, and abdominal pain.
• Headache and dizziness.
• Indigestion (dyspepsia) or bloating, gas (flatulence).
• Itching (pruritus) and hives (urticaria).

Serious side effects, though rare, require immediate medical attention:

• Allergic reactions (rash, swelling of face, lips, throat or tongue, difficulty breathing).
• Signs of liver problems (yellow skin/eyes, dark urine, persistent itching, loss of appetite).
• Severe watery diarrhea, possibly with blood, or persistent diarrhea (pseudomembranous colitis).
• Tendon pain, swelling, or rupture.
• Seizures or convulsions.

Precautions

• Inform your doctor about any existing health conditions, especially liver or kidney problems, diabetes, heart conditions, myasthenia gravis, or a history of seizures/epilepsy or tendon issues.
• This medicine is generally not recommended for pregnant or breastfeeding women. Consult your doctor before use if you are pregnant, planning a pregnancy, or breastfeeding.
• Avoid alcohol consumption during treatment as it may impair your ability to concentrate and react, and may increase certain side effects.
• Exercise caution when driving or operating machinery, as this medicine may cause dizziness or affect vision.
• Zenflox Plus 100 Tablet is not recommended for children and adolescents under 18 years of age.
• Drug Interactions: Inform your doctor about all other medications, supplements, and herbal products you are taking. Certain medications like antacids, iron supplements, blood thinners (e.g., warfarin), corticosteroids, theophylline, and some anti-HIV drugs (e.g., Didanosine) can interact with Zenflox Plus.
• Avoid taking dairy products, calcium-rich foods/supplements, and iron-rich foods/supplements within 2 hours of taking Zenflox Plus, as they can reduce absorption.

Storage

• Store Zenflox Plus 100 Tablet below 30°C in a cool and dry place.
• Protect the medicine from direct sunlight, heat, and moisture.
• Keep out of the sight and reach of children and pets.
• Do not use this medicine after the expiry date printed on the packaging.

What is Zenflox Plus 100 Tablet used for?

Zenflox Plus 100 Tablet, a combination of Cefixime and Ofloxacin, is primarily used to treat a wide range of bacterial infections in adults. These include typhoid fever, and bacterial infections of the respiratory tract (such as tonsillitis, pharyngitis, and bronchitis), middle ear (otitis media), reproductive organs (gonorrhea), and urinary tract. It is also effective against skin and soft tissue infections.

How does Zenflox Plus 100 Tablet work?

Zenflox Plus 100 Tablet contains two active antibiotic ingredients: Cefixime and Ofloxacin. Cefixime works by preventing the formation of the bacterial cell wall, which is essential for the bacteria's survival. Ofloxacin inhibits a bacterial enzyme (DNA gyrase) crucial for DNA replication and repair, thereby preventing bacteria from reproducing and repairing themselves. Together, they effectively kill the infection-causing bacteria.

What is the usual dosage for Zenflox Plus 100 Tablet?

The dosage of Zenflox Plus 100 Tablet is determined by your doctor based on the type and severity of the infection, and your response to treatment. It should be taken as advised by your physician, swallowed whole with a glass of water, and can be taken with or without food. It is crucial to take the medicine at a fixed time for optimal results and to complete the entire course of treatment to prevent antibiotic resistance.

What are the possible side effects of Zenflox Plus 100 Tablet?

Common side effects of Zenflox Plus 100 Tablet include indigestion, nausea, stomach pain, vomiting, diarrhea, gas, headache, dizziness, and itching or skin rash. If these symptoms worsen or persist, or if you experience severe side effects such as allergic reactions (rash, joint pain, difficulty swallowing or breathing, swollen face/lips/tongue), signs of liver disease (yellow skin/eyes, dark urine, itching), or severe watery diarrhea with blood, consult your doctor immediately.

Is Zenflox Plus 100 Tablet safe during pregnancy or breastfeeding?

Zenflox Plus 100 Tablet is generally not recommended for use in pregnant and breastfeeding women due to a lack of adequate and well-controlled studies. It should be used cautiously during pregnancy if the potential benefits outweigh the risks, and it may pass into breast milk, potentially harming the nursing baby. It is advisable to consult your doctor before taking this medicine if you are pregnant or breastfeeding.

Can Zenflox Plus 100 Tablet be taken with other medications?

Zenflox Plus 100 Tablet can interact with various medications. It may interfere with the effectiveness of certain vaccines (e.g., typhoid, cholera, BCG). It can also interact with blood thinners (like warfarin), antiepileptic drugs (like carbamazepine), antacids and ulcer-treating medicines (containing aluminum, magnesium, cimetidine, sucralfate), and medicines or dietary supplements containing iron or zinc, potentially reducing their absorption. Always inform your doctor about all medicines, supplements, or herbal preparations you are taking to avoid possible interactions.

What precautions should be taken while using Zenflox Plus 100 Tablet?

Precautions include informing your doctor if you have a history of mental illness, low potassium or magnesium levels, diabetes, epilepsy or a risk of fits, liver or kidney problems, or a history of tendonitis. Avoid alcohol consumption as it may increase side effects like dizziness and drowsiness. Also, avoid dairy products and calcium-rich foods/supplements within 2 hours of taking Zenflox Plus 100 Tablet, as they can decrease absorption. This medicine may also make you more sensitive to sunlight.

What happens if a dose of Zenflox Plus 100 Tablet is missed?

If you miss a dose of Zenflox Plus 100 Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Zenflox Plus 100 Tablet be stored?

Zenflox Plus 100 Tablet should be stored at room temperature, typically below 30°C, in a cool and dry place. It should be protected from direct sunlight, heat, and moisture, and kept out of the sight and reach of children and pets. Do not use the medicine after its expiry date.