Pancef O Dry Syrup

PANCEF O DRY SYRUP

PANCEF O DRY SYRUP is an antibiotic medication manufactured by Aglowmed Ltd., primarily prescribed for children to treat a variety of bacterial infections.

• Composition:

  • Active Ingredient: Cefixime (50 mg/5ml or 100 mg/5ml, depending on the variant).

• Uses: PANCEF O DRY SYRUP is used to manage bacterial infections in children, including:

  • Ear, nose, throat, and sinus infections (e.g., otitis media, tonsillitis, pharyngitis, sinusitis).
  • Respiratory tract infections (e.g., bronchitis, pneumonia).
  • Urinary tract infections (e.g., cystitis, kidney infections).
  • Skin and soft-tissue infections.
  • Uncomplicated typhoid fever.
  • Some sexually transmitted diseases (gonorrhoea). It works by inhibiting the growth of bacteria by interfering with the synthesis of their cell walls, leading to bacterial death.

• Dosage and Administration:

  • The recommended dosage is based on the child's body weight and the severity of the infection, as prescribed by a doctor.
  • It should be administered as directed by the physician.
  • To prepare the syrup, add boiled and cooled water to the dry powder, shake well, and then top up to the mark on the bottle.
  • Shake the bottle well before each use.
  • Can be given with or without food; however, giving it with food can help avoid an upset stomach.
  • It is crucial to complete the full course of the antibiotic, even if symptoms improve, to prevent the infection from returning or worsening and to reduce antibiotic resistance.

• Side Effects:

  • Common: Diarrhoea, nausea, vomiting, abdominal pain, indigestion, loose stools, headache, dizziness, rash, itching, hives, flatulence.
  • Serious: Allergic reactions (skin rash, itching, swelling of face, lips, throat, or tongue causing difficulty in breathing or swallowing), unusual bleeding or bruising, severe uncontrollable watery diarrhoea, kidney damage, severe gastrointestinal infections. If any side effects persist or worsen, or if severe symptoms occur, medical attention should be sought immediately.

• Precautions:

  • Inform the doctor about any history of allergies to cefixime or other cephalosporin antibiotics (including penicillins).
  • Use with caution in children with kidney disease; dose adjustments may be necessary.
  • Children with gastrointestinal diseases, particularly colitis, should be given this medicine with caution.
  • Avoid using for viral infections like the common cold or flu.
  • Interactions: May interact with anticoagulants (like warfarin) increasing the risk of bleeding, and iron supplements/antacids which can decrease cefixime absorption.
  • Cholera vaccine should be avoided if Pancef O has been taken within 14 days before vaccination.
  • May reduce the effectiveness of oral contraceptive pills.
  • Caution is advised in patients with liver problems or a history of seizures.

• Storage:

  • Store the dry powder below 25°C or below 30°C, protected from direct sunlight, heat, and moisture.
  • Once prepared, the syrup should be stored in a refrigerator between 2-8°C and used within the time specified on the label.
  • Keep out of reach of children and pets.

PANCEF O Dry Syrup (by AGLOWMED LTD.) is an antibiotic medicine that contains Cefixime as its active ingredient. It is commonly prescribed to treat a variety of bacterial infections.

What is PANCEF O Dry Syrup used for?

PANCEF O Dry Syrup is used to treat a wide range of bacterial infections. These include infections of the ear, nose, throat (such as tonsillitis and pharyngitis), sinuses (sinusitis), lungs (bronchitis and pneumonia), and the urinary system (bladder and kidney infections, cystitis). It is also effective in treating uncomplicated typhoid fever and certain sexually transmitted diseases like uncomplicated gonorrhea. This medicine is not effective against viral infections like the common cold or flu.

How does PANCEF O Dry Syrup work?

PANCEF O Dry Syrup contains Cefixime, which is a cephalosporin antibiotic. It works by preventing the growth and replication of bacteria. Specifically, it inhibits the synthesis of the bacterial cell wall, which is vital for the bacteria's survival. This action weakens and eventually destroys the bacterial cell, leading to its death and clearing the infection.

What is the usual dosage for PANCEF O Dry Syrup?

The dosage of PANCEF O Dry Syrup depends on the patient's age, weight (for children), and the severity of the infection, and should always be determined by a doctor. For adults and children over 10 years of age or weighing more than 50 kg, the recommended dose is typically 200-400 mg daily, given as a single dose or in two divided doses. For children aged 6 months to 12 years (or weighing less than 50 kg), the usual dosage is 8 mg per kg of body weight per day, which can be given as a single daily dose or divided into two doses (4 mg/kg every 12 hours). It is crucial to shake the bottle well before each use and accurately measure the dose using a special measuring device provided or recommended by your pharmacist. This medication can be taken with or without food. The usual course of treatment is 7 to 14 days, and it is important to complete the entire prescribed course even if symptoms improve to prevent antibiotic resistance and ensure effective treatment.

What are the possible side effects of PANCEF O Dry Syrup?

Common side effects may include nausea, vomiting, stomach pain or upset, indigestion, diarrhea, gas, headache, dizziness, and loose stools. These are usually mild and temporary. More serious but rare side effects can include severe allergic reactions (such as rash, itching, swelling of the face, lips, throat or tongue, and difficulty breathing), severe or persistent watery or bloody diarrhea (which could indicate a serious intestinal condition), severe abdominal cramps, yellowing of the skin or eyes (jaundice), dark urine, unusual tiredness, easy bruising or bleeding, signs of kidney problems (like a change in urine amount), mental or mood changes (such as confusion), and seizures. If you experience any severe or persistent side effects, or signs of an allergic reaction, seek immediate medical attention.

Is PANCEF O Dry Syrup safe during pregnancy or breastfeeding?

During Pregnancy: Limited safety information is available regarding the use of PANCEF O Dry Syrup during pregnancy. It should only be used if clearly considered essential by your doctor, as it is known to cross the placenta. During Breastfeeding: It is unknown whether Cefixime passes into breast milk. If you are treated with PANCEF O Dry Syrup, it is generally advised to discontinue nursing temporarily. If taken while breastfeeding, monitor the baby for potential side effects such as diarrhea. Always consult your doctor for advice if you are pregnant or breastfeeding.

Can PANCEF O Dry Syrup be taken with other medications?

It is important to inform your doctor about all prescription and non-prescription medications, vitamins, nutritional supplements, and herbal products you are currently taking or plan to take. PANCEF O Dry Syrup can interact with certain medications. For example, it may alter the effects of blood thinners like Warfarin, potentially increasing the risk of bleeding. Iron supplements and antacids can reduce the absorption of Cefixime. It may also decrease the effectiveness of live bacterial vaccines (e.g., cholera vaccine, typhoid vaccine) and hormonal birth control, so additional contraception may be needed. Taking it with aminoglycosides or other cephalosporin antibiotics might increase the risk of kidney damage.

What precautions should be taken while using PANCEF O Dry Syrup?

Do not use PANCEF O Dry Syrup for viral infections. Inform your doctor if you have known allergies to cefixime, penicillins, or other cephalosporin antibiotics. Exercise caution and inform your doctor if you have kidney or liver problems, or a history of gastrointestinal diseases, especially colitis. Avoid consuming alcohol while taking this antibiotic. If you experience side effects such as confusion, altered consciousness, or fits, do not drive or operate machinery. Always complete the full course of treatment as prescribed by your doctor, even if you start feeling better, to prevent the infection from returning and to avoid antibiotic resistance.

What happens if a dose of PANCEF O Dry Syrup is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

How should PANCEF O Dry Syrup be stored?

Before reconstitution (mixing with water), PANCEF O Dry Syrup should be stored below 25°C or 30°C, protected from direct sunlight, heat, and moisture. Keep it out of the reach of children and pets. Once the dry powder is mixed with boiled and cooled water to form the syrup, it should be stored in a refrigerator (between 2-8°C). Discard any unused reconstituted syrup after the time specified on the label, usually within 7 to 14 days.