Nervmax D 75/20 Cap

NERVMAX D 75/20 Capsule is a combination medication used for the management of various forms of neuropathic pain and associated conditions. It is manufactured by Alkem Laboratories Ltd..

Composition

Each capsule contains:

• Pregabalin: 75 mg
• Duloxetine: 20 mg

Uses

NERVMAX D 75/20 is primarily prescribed for the treatment of neuropathic pain, which includes:

• Peripheral neuropathic pain (e.g., caused by diabetes or shingles)
• Diabetic neuropathy
• Postherpetic neuralgia
• Fibromyalgia
• Generalized chronic pain conditions and anxiety disorders often linked with chronic nerve pain. It helps to reduce pain signals and improve mental well-being.

Dosage and Administration

This medicine should be taken orally, with or without food, as directed by a healthcare professional. It is usually administered once or twice daily, and it's essential to take it at the same time each day to maintain consistent levels in the body. Capsules should be swallowed whole and not crushed, chewed, or broken. Do not stop the medication abruptly without consulting your doctor, as this can lead to withdrawal symptoms.

Side Effects

Common side effects may include:

• Dizziness, sleepiness, headache
• Nausea, vomiting, constipation, dry mouth
• Blurred vision, weight gain, increased appetite
• Swelling of the hands and feet (peripheral edema)
• Difficulty sleeping (insomnia), increased sweating, loss of appetite, tingling or numbness, reduced sex drive, and difficulty concentrating.

Serious side effects, though less common, can include changes in mood or behavior, suicidal thoughts, muscle pain or weakness, and severe allergic reactions.

Precautions

• Allergies: Avoid if allergic to Pregabalin, Duloxetine, or any other components.
• Alcohol: Avoid consuming alcohol, as it can increase dizziness and drowsiness and may lead to liver damage.
• Driving/Operating Machinery: Exercise caution when driving or operating heavy machinery due to potential drowsiness or dizziness.
• Medical Conditions: Inform your doctor if you have kidney or liver disease, heart conditions, diabetes, glaucoma, bleeding disorders, or a history of depression, suicidal thoughts, mania, or bipolar disorder.
• Pregnancy and Breastfeeding: Generally considered unsafe during pregnancy and breastfeeding; consult your doctor.
• Drug Interactions: Inform your doctor about all other medications, supplements, and herbal products you are taking to prevent potential interactions, especially with other antidepressants or CNS depressants.
• Dependency: This medicine has the potential for dependency, particularly due to the Pregabalin component.

Storage

Store NERVMAX D 75/20 Capsules at room temperature, below 30°C, in a cool and dry place away from direct sunlight. Keep out of the sight and reach of children.

What is NERVMAX D 75/20 CAP used for?

NERVMAX D 75/20 CAP is primarily used to manage neuropathic pain, a type of long-lasting pain caused by nerve damage or malfunction. This includes conditions such as diabetic neuropathic pain, fibromyalgia, and postherpetic neuralgia. It may also be used in the management of anxiety disorders.

How does NERVMAX D 75/20 CAP work?

This medicine contains two active ingredients: Pregabalin (75mg) and Duloxetine (20mg). Pregabalin, an anticonvulsant, works by controlling the activity of calcium channels in overactive nerve cells, which helps to block pain signals. Duloxetine, a selective serotonin reuptake inhibitor (SSRI), increases the levels of certain chemical messengers in the brain, such as serotonin and norepinephrine, which play a role in regulating pain, mood, and mental balance. The combined action helps to reduce pain signals and improve overall well-being.

What is the usual dosage of NERVMAX D 75/20 CAP?

NERVMAX D 75/20 CAP should be taken exactly as prescribed by your doctor. It is typically administered orally, with or without food, once or twice a day. It is important to take the capsule at the same time each day to maintain consistent medication levels in your body. Do not chew, crush, or break the capsule; swallow it whole with a glass of water. Your doctor may start with a low dose and gradually increase it based on your response and tolerance.

What are the possible side effects of NERVMAX D 75/20 CAP?

Common side effects may include dizziness, drowsiness, headache, dry mouth, nausea, constipation, increased sweating, loss of appetite, blurred vision, weight gain, fatigue, and difficulty sleeping. Some individuals may also experience tingling or numbness, or a reduced sex drive. In rare cases, it may cause changes in mood or behavior, including suicidal thoughts. If any side effects persist or worsen, you should inform your doctor.

Is NERVMAX D 75/20 CAP safe during pregnancy or breastfeeding?

NERVMAX D 75/20 CAP is generally not recommended for use during pregnancy, especially in the last trimester, as it may cause fetal abnormalities. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. It is considered unsafe during breastfeeding as its components may be excreted in breast milk.

Can NERVMAX D 75/20 CAP be taken with other medications?

It is crucial to inform your doctor about all other medications, supplements, and herbal products you are currently taking to avoid potential drug interactions. This medicine can interact with certain medications, including other antidepressants, CNS depressants (like sedatives and benzodiazepines), and some blood pressure medications. Alcohol consumption should be avoided as it can increase drowsiness, dizziness, and the risk of liver damage.

What precautions should be taken while taking NERVMAX D 75/20 CAP?

Do not stop taking NERVMAX D 75/20 CAP suddenly without your doctor's advice, as abrupt discontinuation can lead to withdrawal symptoms like dizziness, tingling sensations, sleep disturbances, restlessness, nausea, vomiting, headache, or excessive sweating. Caution is advised if you have liver or kidney disease, seizures (fits), mania, bipolar disorder, depression (due to increased risk of suicidal thoughts), glaucoma, bleeding disorders, or hypertension. This medicine may cause drowsiness or dizziness, so avoid driving or operating machinery until you understand how it affects you. It is not recommended for children below 18 years of age.

What happens if a dose of NERVMAX D 75/20 CAP is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should NERVMAX D 75/20 CAP be stored?

NERVMAX D 75/20 CAP should be stored in a cool and dry place, preferably below 30°C. Protect it from moisture and direct sunlight. Keep the medicine out of the sight and reach of children.