Glizid-m 40/500

GLIZID-M 40/500

Name: GLIZID-M 40/500 Tablet (Brand name: GLIZID-M)

Composition: Each tablet contains:

• Gliclazide: 40 mg
• Metformin Hydrochloride: 500 mg

Uses: GLIZID-M 40/500 is prescribed for the management of Type 2 Diabetes Mellitus in adults. It is used when diet, exercise, and weight loss alone are insufficient to control blood sugar levels. This medication helps to:

• Control blood sugar levels.
• Reduce the risk of serious diabetes complications such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), nerve damage (diabetic neuropathy), and foot ulcers.
• Contribute to better cardiovascular health and reduce the risk of heart attack or stroke in diabetic patients.

Dosage and Administration: GLIZID-M 40/500 should be taken with food, usually once or twice daily. It is advised to take the medicine at the same time each day for optimal results. The tablets should be swallowed whole with a glass of water and not crushed, chewed, or split. The precise dosage will be determined by a healthcare professional based on the individual's blood sugar levels and response to treatment. Do not discontinue the medication without consulting your doctor.

Side Effects:

• Common Side Effects: Hypoglycemia (low blood sugar), which may manifest as dizziness, sweating, palpitations, hunger pangs, unusual sleepiness, shivering, and dry mouth. Other common effects include stomach ache, indigestion, nausea, vomiting, diarrhea, constipation, altered taste, headache, and upper respiratory symptoms.
• Serious Side Effects (Rare): Lactic acidosis, characterized by deep or rapid breathing, persistent nausea, vomiting, and stomach pain. Long-term use may also lead to Vitamin B12 deficiency. Consult your doctor if any side effects persist or worsen.

Precautions:

• GLIZID-M 40/500 is not recommended for Type 1 diabetes, diabetic ketoacidosis, or severe liver or kidney disease.
• Exercise caution and inform your doctor if you have a history of heart disease, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or hemolytic anemia.
• Alcohol consumption should be avoided while taking this medicine as it can increase the risk of hypoglycemia and lactic acidosis.
• Inform your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
• The medication may cause hypoglycemia, which can affect your ability to drive or operate machinery; use caution.
• Regular monitoring of blood sugar levels, kidney function, and vitamin B12 and thyroid-stimulating hormone (TSH) levels is suggested.
• Do not take GLIZID-M 40/500 if you are allergic to any of its components.

Storage: Store GLIZID-M 40/500 in a cool and dry place, ideally below 30°C (or 25°C). Protect the medicine from direct sunlight, light, and moisture. Keep it out of sight and reach of children.

What is GLIZID-M 40/500 used for?

GLIZID-M 40/500 is used to treat Type 2 diabetes mellitus in adults. It helps control high blood sugar levels when diet, exercise, and weight loss alone are not sufficient. This medication also helps reduce the risk of serious diabetes complications such as kidney damage, blindness, nerve problems, heart attack, and stroke.

How does GLIZID-M 40/500 work?

GLIZID-M 40/500 is a combination medicine containing Gliclazide (40mg) and Metformin (500mg). Gliclazide works by stimulating the pancreas to release more insulin. Metformin works by decreasing glucose production in the liver, delaying the absorption of glucose from the intestines, and improving the body's sensitivity to insulin. Together, these actions help to lower and control blood sugar levels.

What is the usual dosage for GLIZID-M 40/500?

GLIZID-M 40/500 should be taken with food, usually once or twice daily, or as prescribed by your doctor. It is important to take it at the same time each day for the best results. The tablets should be swallowed whole with water and not chewed, crushed, or broken. Your doctor will determine the appropriate dose based on your blood sugar levels and response to treatment.

What are the possible side effects of GLIZID-M 40/500?

Common side effects may include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain or indigestion, diarrhea, headache, vomiting, and constipation.

Serious but rare side effects can include lactic acidosis, characterized by symptoms like deep or rapid breathing, persistent nausea, vomiting, and stomach pain, and potentially vitamin B12 deficiency with long-term use. If you experience symptoms of low blood sugar such as dizziness, sweating, palpitations, hunger pangs, or unusual sleepiness, it is important to treat it immediately.

Is GLIZID-M 40/500 safe during pregnancy or breastfeeding?

GLIZID-M 40/500 is generally considered unsafe for use during pregnancy, as there is evidence of risk to the developing baby. It is also probably unsafe and not recommended during breastfeeding. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medication.

Can GLIZID-M 40/500 be taken with other medications?

GLIZID-M 40/500 can interact with other medications. The risk of hypoglycemia may increase if taken with other antidiabetic agents (like insulin), ACE inhibitors (e.g., captopril, enalapril), beta-blockers, fluconazole, or NSAIDs (e.g., ibuprofen). It should be avoided with miconazole. Conversely, medications like glucocorticoids (e.g., prednisolone) may reduce its effectiveness. It is crucial to inform your doctor about all medicines, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while taking GLIZID-M 40/500?

Do not take GLIZID-M 40/500 if you have Type 1 diabetes, diabetic ketoacidosis, severe liver or kidney disease, or are allergic to any of its ingredients. Alcohol consumption should be avoided as it can increase the risk of hypoglycemia and lactic acidosis. Regular blood sugar monitoring is important, and you should carry a form of sugar to treat any sudden drops in blood sugar. Use caution when driving or operating machinery, as blood sugar fluctuations can affect your ability to concentrate. Do not stop taking the medicine without consulting your doctor. Your doctor may also recommend annual blood tests to check vitamin B12 levels and thyroid-stimulating hormone (TSH).

What happens if a dose of GLIZID-M 40/500 is missed?

If you miss a dose of GLIZID-M 40/500, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should GLIZID-M 40/500 be stored?

GLIZID-M 40/500 should be stored in a cool and dry place, away from direct sunlight, moisture, and heat. Keep it out of sight and reach of children. The ideal storage temperature is below 30°C. Do not freeze the medicine.