Valentas 50 Mg Tablet ( 10 Tab )

VALENTAS 50 MG TABLET

Name

• Brand Name: Valentas 50 MG Tablet
• Common Name: Sacubitril and Valsartan

Composition

VALENTAS 50 MG TABLET is a combination medication containing two active ingredients:

• Sacubitril (24 mg)
• Valsartan (26 mg)

Uses

VALENTAS 50 MG TABLET is primarily used for the treatment of heart failure with reduced ejection fraction in adult patients. It helps to reduce the risk of cardiovascular death and hospitalization for heart failure in individuals with chronic heart failure (New York Heart Association Class II-IV). It works by relaxing and widening blood vessels, making it easier for the heart to pump blood throughout the body, and helps the body retain less water.

Dosage and Administration

This medicine should be taken in the dose and duration as advised by your doctor. It can be taken with or without food, but it is recommended to take it at the same time each day for maximum benefits. Do not chew, crush, or break the tablet; swallow it whole with a glass of water. Do not stop taking Valentas Tablet suddenly, as it may worsen your condition.

Side Effects

Common Side Effects:

• Dizziness, light-headedness (low blood pressure)
• Cough
• Headache
• Tiredness, weakness, fatigue
• Nausea
• Diarrhea
• High potassium levels in the blood (hyperkalemia)
• Impaired renal function / decrease in renal function

Serious Side Effects (Seek immediate medical attention if experienced):

• Severe allergic reactions such as swelling of the face, lips, tongue, or throat (angioedema), which may cause difficulties in breathing or swallowing.

Precautions

• Pregnancy: VALENTAS 50 MG TABLET is contraindicated during pregnancy, especially after the first 3 months, as it may cause serious harm to the baby.
• Breastfeeding: Not recommended for use in breastfeeding women as it may pass into breastmilk and harm the baby.
• Allergy: Do not take if allergic to sacubitril, valsartan, or any other ingredients, or if you have a history of angioedema with ACE inhibitors or ARBs.
• Drug Interactions: Inform your doctor about all other medicines, herbal preparations, and supplements you are currently taking to avoid possible drug interactions. Do not take VALENTAS 50 MG TABLET with ACE inhibitors; a washout period of at least 36 hours is required after taking the last dose of an ACE inhibitor.
• Medical Conditions: Use with caution in patients with kidney disease (especially severe impairment) or liver disease. Regular monitoring of blood pressure and kidney function is advised.
• Driving and Operating Machinery: This medicine may cause dizziness or tiredness; avoid driving or operating heavy machinery if you experience these symptoms.
• Potassium-rich foods: Avoid taking potassium supplements and eating potassium-rich foods like bananas and broccoli, as this medicine may raise blood potassium levels.
• Alcohol: It is advisable to avoid alcohol as it may increase the blood pressure-lowering effect and risk of dizziness.

Storage

Store VALENTAS 50 MG TABLET at room temperature, ideally not exceeding 30°C. Keep it in its original packaging, away from moisture and direct light. Ensure the medicine is kept out of the sight and reach of children.

Here are the most frequently asked questions about VALENTAS 50 MG TABLET:

What is VALENTAS 50 MG TABLET used for?

VALENTAS 50 MG TABLET is a combination medication primarily used to treat chronic heart failure in adults. It helps to reduce the risk of hospitalization and death by improving the heart's pumping ability and alleviating symptoms such as shortness of breath, fatigue, and swelling in the ankles and feet.

How does VALENTAS 50 MG TABLET work?

This medicine contains two active ingredients: sacubitril and valsartan. Sacubitril inhibits an enzyme called neprilysin, which increases the levels of beneficial natriuretic peptides in the body. These peptides help to relax and widen blood vessels and reduce sodium and fluid retention. Valsartan is an angiotensin receptor blocker (ARB) that works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict and increases blood pressure. Together, these actions relax blood vessels, reduce the heart's workload, and improve heart function.

What is the usual dosage for VALENTAS 50 MG TABLET?

VALENTAS 50 MG TABLET should be taken orally as instructed by your doctor, with or without food, preferably at the same time each day for maximum benefit. The dose and frequency will be determined by your doctor based on your medical condition and response to treatment. Do not chew, crush, or break the tablet.

What are the possible side effects of VALENTAS 50 MG TABLET?

Common side effects may include low blood pressure (hypotension) leading to dizziness or lightheadedness, increased potassium levels in the blood (hyperkalemia), cough, and kidney impairment. Less common side effects can include headache, nausea, diarrhea, tiredness, and fainting. If you experience any severe or persistent side effects, you should consult your doctor.

Is VALENTAS 50 MG TABLET safe during pregnancy or breastfeeding?

VALENTAS 50 MG TABLET is not recommended during pregnancy and must not be used after the first three months of pregnancy as it can cause serious harm to the unborn baby. It is also not recommended for use in breastfeeding women. If you are pregnant, planning to conceive, or breastfeeding, you should consult your doctor for safer alternatives.

Can VALENTAS 50 MG TABLET be taken with other medications?

VALENTAS 50 MG TABLET can interact with several other medications. It should not be taken with ACE inhibitors (e.g., enalapril, lisinopril) and a waiting period of at least 36 hours is required if switching between these medications. Concomitant use with blood pressure-lowering medicines, potassium supplements or potassium-sparing diuretics (e.g., spironolactone), non-steroidal anti-inflammatory drugs (NSAIDs), and aliskiren is generally not recommended or requires caution and close monitoring by your doctor. Always inform your doctor about all medications, supplements, and herbal products you are currently taking.

What precautions should be taken while using VALENTAS 50 MG TABLET?

Patients with a history of angioedema (swelling of the face, lips, tongue, or throat) or severe liver disease should avoid this medicine. Caution is also advised for patients with kidney disease, and regular kidney function tests may be necessary. This medicine may cause dizziness or lightheadedness, so it is advisable to avoid driving or operating heavy machinery if you experience these symptoms. Discuss alcohol intake with your doctor as it may amplify blood pressure-lowering effects and increase dizziness.

What happens if a dose of VALENTAS 50 MG TABLET is missed?

If you miss a dose of VALENTAS 50 MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

How should VALENTAS 50 MG TABLET be stored?

VALENTAS 50 MG TABLET should be stored at room temperature, typically below 30°C, and away from moisture and direct light. Keep the medicine out of the sight and reach of children and pets.