Encelin M 50/500 Tab

ENCELIN M 50/500 TABLET

ENCELIN M 50/500 TABLET is a medication manufactured by Torrent Pharmaceuticals Ltd., designed for the management of Type 2 Diabetes Mellitus.

• Name:

  • Brand Name: ENCELIN M 50/500 TABLET
  • Common Names: Vildagliptin/Metformin combination tablet

• Composition:

  • Each tablet contains Vildagliptin 50 mg and Metformin Hydrochloride 500 mg.

• Uses: ENCELIN M 50/500 TABLET is prescribed for adults with Type 2 Diabetes Mellitus to improve blood sugar control. It is typically used when diet and exercise alone, or in combination with other anti-diabetic medications, do not provide adequate blood sugar regulation. This combination works by increasing insulin secretion, decreasing glucagon production, reducing glucose production in the liver, and enhancing the body's sensitivity to insulin.

• Dosage and Administration: This medicine is usually taken once or twice daily, as directed by a healthcare professional. It is recommended to take the tablet with or after meals to minimize gastrointestinal side effects. The tablet should be swallowed whole and should not be crushed or chewed.

• Side Effects:

  • Common: Diarrhea, stomach pain, nausea, vomiting, metallic taste, headache, loss of appetite, low blood glucose (hypoglycemia), joint pain, tiredness, constipation, and swollen extremities (oedema).
  • Serious: Rare but serious side effects include lactic acidosis (symptoms like severe tiredness, difficulty breathing, muscle cramps, and stomach pain) and pancreatitis (severe abdominal pain). Immediate medical attention is required if these occur.

• Precautions: ENCELIN M 50/500 TABLET is not recommended for individuals with Type 1 Diabetes Mellitus, severe kidney disease, severe liver disease, or diabetic ketoacidosis. Caution is advised for elderly patients and those with heart problems. Alcohol consumption should be avoided due to an increased risk of lactic acidosis. It is generally not recommended during pregnancy or breastfeeding unless specifically advised by a doctor. Inform your doctor about any pre-existing medical conditions, especially kidney, liver, or heart issues, or a history of pancreatitis.

• Storage: Store ENCELIN M 50/500 TABLET in a cool, dry place, protected from direct sunlight, heat, and moisture. Keep the medicine out of reach of children. It should be stored at 10ºC to 25ºC or below 30ºC.

ENCELIN M 50/500 TAB: Frequently Asked Questions

What is ENCELIN M 50/500 TAB used for?

ENCELIN M 50/500 TAB is a combination medication used to manage Type 2 Diabetes Mellitus in adults. It helps control high blood sugar levels when diet and exercise alone are insufficient or when other diabetes medications are not providing adequate control. By improving blood sugar regulation, it helps reduce the risk of diabetes-related complications such as kidney damage, eye damage, nerve problems, heart disease, and stroke.

How does ENCELIN M 50/500 TAB work?

This medication contains two active ingredients: Vildagliptin (50 mg) and Metformin (500 mg). Metformin works by decreasing glucose production in the liver, reducing sugar absorption from the intestines, and increasing the body's sensitivity to insulin. Vildagliptin is a DPP-4 inhibitor that works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels, particularly after meals. Together, these components effectively improve insulin sensitivity and regulate blood sugar levels.

What is the usual dosage of ENCELIN M 50/500 TAB?

ENCELIN M 50/500 TAB is typically taken once or twice daily, as prescribed by your doctor, usually with or after meals. Taking it with food can help improve tolerance to metformin and reduce side effects like nausea. The specific dosage is personalized based on individual conditions, current blood sugar levels, and any other medications being taken.

What are the possible side effects of ENCELIN M 50/500 TAB?

Common side effects may include diarrhea, stomach pain, loss of appetite, metallic taste, nausea, vomiting, headache, low blood glucose (hypoglycemia), joint pain, tiredness, constipation, and upper respiratory tract infections. Serious, but rare, side effects can include lactic acidosis (symptoms like vomiting, stomach pain, decreased heartbeat, difficulty breathing, muscle cramps, severe tiredness) and inflamed pancreas (severe and persistent abdominal pain). Seek immediate medical attention if you experience any serious side effects.

Is ENCELIN M 50/500 TAB safe during pregnancy or breastfeeding?

ENCELIN M 50/500 TAB is generally not recommended during pregnancy unless considered necessary and specifically advised by a doctor, due to limited information on its safety. It is contraindicated during breastfeeding as its components are known to pass into breast milk, and it may not be safe for the baby. Always consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding.

Can ENCELIN M 50/500 TAB be taken with other medications?

This medicine can interact with certain other medications. Inform your doctor about all medicines, supplements, or herbal products you are taking. Interactions can occur with:

• Glucocorticoids (e.g., dexamethasone, prednisolone)
• Beta-2 agonists (e.g., albuterol, terbutaline)
• Diuretics (e.g., chlorthalidone, hydrochlorothiazide)
• NSAIDs (e.g., ibuprofen, celecoxib)
• Angiotensin-converting enzyme (ACE) inhibitors (e.g., enalapril, lisinopril)
• Angiotensin II receptor antagonists (e.g., losartan, telmisartan)
• Other antidiabetic medications
• Cationic medications (e.g., amiloride, digoxin, trimethoprim)
• Iodinated contrast agents
• CYP3A4 inducers (e.g., rifampicin)

What precautions should be taken while taking ENCELIN M 50/500 TAB?

ENCELIN M 50/500 TAB is not suitable for Type 1 diabetes or diabetic ketoacidosis. Inform your doctor if you have kidney, liver, or heart problems, a history of pancreatitis, or low vitamin B12 levels. Avoid alcohol consumption as it can increase the risk of a serious condition called lactic acidosis. Regular monitoring of blood sugar levels, kidney function, and liver enzymes is essential during treatment. If you experience dizziness, avoid driving or operating machinery.

What happens if a dose of ENCELIN M 50/500 TAB is missed?

If you miss a dose of ENCELIN M 50/500 TAB, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one without consulting your doctor.

How should ENCELIN M 50/500 TAB be stored?

Store ENCELIN M 50/500 TAB in a cool, dry place, away from direct sunlight, heat, and moisture. Keep it out of sight and reach of children. Always check the expiry date and discard any outdated medicine properly.