Esomac L Capsule (10 Cap)

ESOMAC L CAPSULE (10 CAP) by CIPLA LTD.

ESOMAC L Capsule is a combination medicine manufactured by Cipla Ltd., used to manage various acid-related gastrointestinal conditions.

• Name:

  • Brand Name: ESOMAC L Capsule

• Composition: Each capsule contains:

  • Esomeprazole Magnesium: 40 mg (as enteric-coated pellets)
  • Levosulpiride: 75 mg (as sustained-release pellets) Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production, while Levosulpiride is a prokinetic agent that enhances stomach and intestinal movement.

• Uses: ESOMAC L Capsule is primarily prescribed for:

  • Gastroesophageal Reflux Disease (GERD), which includes acid reflux, heartburn, stomach irritation, and difficulty swallowing.
  • Peptic Ulcers (ulcers in the stomach or intestine).
  • Acidity and dyspepsia.
  • Diabetic gastroparesis and functional dyspepsia.

• Dosage and Administration:

  • The typical recommended dose is one capsule once daily.
  • It should be swallowed whole with liquid, preferably one hour before a meal (often in the morning), and should not be chewed or crushed.
  • The exact dosage and duration will be determined by a doctor based on the patient's condition and response to the medicine.

• Side Effects: Common side effects may include:

  • Headache
  • Diarrhoea
  • Nausea and Vomiting
  • Abdominal pain/Upset stomach
  • Constipation
  • Flatulence (excessive gas)
  • Dry mouth
  • Dizziness or sleepiness

  Serious side effects, though less common, can include severe allergic reactions, electrolyte imbalance, or severe gastrointestinal discomfort. Long-term use may also be associated with an increased risk of bone fractures and fundic gland polyps.

• Precautions:

  • Pregnancy and Breastfeeding: Caution is advised. It is generally not recommended during pregnancy or breastfeeding.
  • Alcohol: Avoid alcohol consumption as it can intensify side effects like drowsiness and increase stomach acid production.
  • Liver and Kidney Impairment: Use with caution in patients with severe liver or kidney problems. Dose adjustment may be necessary.
  • Driving and Operating Machinery: May cause dizziness or drowsiness, so activities requiring mental focus should be avoided until the medicine's effects are known.
  • Drug Interactions: Inform your doctor about all other medications, supplements, or herbal preparations, especially cardiac glycosides (e.g., digoxin), immunosuppressants (e.g., tacrolimus), antiplatelet agents (e.g., clopidogrel), anti-cancer medications (e.g., methotrexate), anti-fungal medicines, anti-HIV medicines, or medicines for brain and heart-related disorders.
  • Other Conditions: Inform your doctor if you have conditions like pheochromocytoma, Parkinson's disease, pituitary tumours, gastrointestinal bleeding, intestinal obstruction, epilepsy, or low magnesium/B12 levels.

• Storage:

  • Store in a cool, dry place.
  • Protect from light.
  • Keep out of sight and reach of children.
  • Do not use after the expiry date.

Here are some frequently asked questions about ESOMAC L CAPSULE (10 CAP) by CIPLA LTD., along with concise answers:

What is Esomac L Capsule used for?

Esomac L Capsule is primarily used to treat gastroesophageal reflux disease (GERD), a condition where stomach acid flows back into the food pipe, causing symptoms like heartburn, acid reflux, and difficulty swallowing. It also helps manage stomach irritation, gastric ulcers, peptic ulcers, diabetic gastroparesis (delayed stomach emptying in diabetics), and functional dyspepsia (chronic indigestion without an identifiable cause).

How does Esomac L Capsule work?

Esomac L Capsule contains two active ingredients: Esomeprazole and Levosulpiride. Esomeprazole is a proton pump inhibitor (PPI) that works by reducing the amount of acid produced in the stomach. Levosulpiride is a prokinetic agent and a selective dopamine D2 receptor antagonist that increases the movement of the stomach and intestines and enhances the pressure of the lower esophageal sphincter, preventing the backflow of food and acid into the food pipe.

What is the usual dosage for Esomac L Capsule?

The recommended dosage is typically one capsule once daily, as directed by your doctor. It should be swallowed whole with liquid, preferably one hour before a meal, usually in the morning. Do not chew or crush the capsule. Your doctor will determine the exact dosage and duration based on your condition and response to the medicine.

What are the possible side effects of Esomac L Capsule?

Common side effects include headache, diarrhea, nausea, abdominal pain, constipation, dry mouth, dizziness, flatulence, and vomiting. Less common but serious side effects can include unusual weight loss, problems swallowing, vomiting blood, black stools, sudden wheezing, swelling (lips, tongue, throat), rash, fainting, yellow skin, dark urine, and tiredness. Long-term use may also lead to decreased magnesium levels, which can cause fatigue, muscle weakness, irregular heartbeat, or seizures, and may increase the risk of bone fractures.

Is Esomac L Capsule safe during pregnancy or breastfeeding?

Esomac L Capsule is generally not recommended during pregnancy or breastfeeding. Caution is advised, and it should only be used if the potential benefits outweigh the risks, and strictly under a doctor's guidance. It is not known if Esomeprazole passes into breast milk, and there is insufficient information on the effects of Esomeprazole in newborns/infants.

Can Esomac L Capsule be taken with other medications?

Esomac L Capsule can interact with various medications. It should not be used concomitantly with nelfinavir (for HIV infection). Co-administration with atazanavir is not recommended. Caution is advised with drugs like warfarin (blood thinner), methotrexate (cancer medication), digoxin (cardiac glycoside), tacrolimus (immunosuppressant), clopidogrel (antiplatelet), and clarithromycin (antibiotic) as interactions can occur. Always inform your doctor about all medicines, supplements, or herbal preparations you are taking.

What precautions should be taken while using Esomac L Capsule?

Inform your doctor if you have severe liver or kidney problems, pheochromocytoma, Parkinson's disease, or pituitary tumors. Long-term use may increase the risk of bone fractures and may reduce the absorption of vitamin B12 and magnesium levels. Avoid alcohol consumption as it can intensify some side effects and increase stomach acid production. This medicine may cause dizziness or drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. It is also contraindicated in patients with known hypersensitivity to its components.

What happens if a dose of Esomac L Capsule is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Esomac L Capsule be stored?

Esomac L Capsule should be stored in a cool, dry place, protected from light, and kept out of sight and reach of children. Store it at temperatures not exceeding 30°C.