Sacuval 200 Tab

SACUVAL 200 Tablet

SACUVAL 200 Tablet is a prescription medication manufactured by Alkem Laboratories Ltd.. It is an angiotensin receptor-neprilysin inhibitor (ARNI) used to treat heart conditions.

• Name:

  • Brand Name: SACUVAL 200 Tablet
  • Common Name: Sacubitril/Valsartan

• Composition:

  • Each tablet contains Sacubitril 97 mg and Valsartan 103 mg.

• Uses:

  • SACUVAL 200 Tablet is primarily used to treat chronic heart failure in adults.
  • It helps reduce the risk of cardiovascular death and hospitalization in adults with certain types of heart failure.
  • The medicine works by relaxing and widening blood vessels, making it easier for the heart to pump blood effectively, and reducing the workload on the heart.
  • It may also be used in children aged 1 to less than 18 years old to treat heart failure.
  • Additionally, it can aid in hypertension management and provide cardiovascular protection.

• Dosage and Administration:

  • Take SACUVAL 200 Tablet exactly as prescribed by your doctor.
  • It can be taken with or without food.
  • It is advisable to take the tablet at around the same time each day for consistent absorption and effectiveness.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or split it.
  • Do not stop taking the medicine even if you feel well, as it helps prevent future complications.

• Side Effects:

  • Common Side Effects: Low blood pressure (hypotension), dizziness, increased potassium levels (hyperkalemia), cough, and renal impairment (kidney damage/abnormalities).
  • Serious Side Effects: Angioedema (swelling of the face, lips, tongue, and throat, with difficulties in breathing). Seek immediate medical attention if this occurs.

• Precautions:

  • Do not take SACUVAL 200 Tablet if you are allergic to Sacubitril, Valsartan, or any of its other ingredients.
  • Avoid if you have a history of angioedema.
  • Not recommended during pregnancy or breastfeeding due to potential risks to the baby.
  • Inform your doctor if you have severe liver disease, severe kidney disease, low blood pressure, dehydration, or diabetes.
  • Avoid taking with ACE inhibitors; a washout period of at least 36 hours is required when switching from an ACE inhibitor.
  • Avoid use with medications containing Aliskiren, especially in patients with diabetes or impaired kidney function.
  • Inform your doctor about all other medications you are taking, including potassium-sparing diuretics, as interactions can occur.
  • Avoid consuming alcohol, as it may increase dizziness.
  • Not recommended for use in children below one year of age.
  • Regular monitoring of blood pressure, kidney function, and potassium levels is recommended.
  • Avoid potassium-rich foods (e.g., bananas, oranges, broccoli) and supplements unless advised by your doctor, as this medicine may increase potassium levels.

• Storage:

  • Store in a cool and dry place, preferably below 30°C (or between 10ºC to 25ºC).
  • Protect from light and moisture.
  • Keep out of the sight and reach of children and pets.

SACUVAL 200 TAB is a medication prescribed primarily for the treatment of heart failure. It is a combination drug containing sacubitril and valsartan.

Here are some frequently asked questions about SACUVAL 200 TAB:

What is SACUVAL 200 TAB used for?

SACUVAL 200 TAB is used to treat chronic heart failure in adults and children over one year of age. It helps reduce the risk of hospitalization and death in individuals with this condition. The medicine works to improve heart function, lessen symptoms like breathlessness and fatigue, and enhance the overall quality of life for heart failure patients.

How does SACUVAL 200 TAB work?

SACUVAL 200 TAB is a combination of two active ingredients: sacubitril and valsartan, belonging to a class of drugs called Angiotensin Receptor-Neprilysin Inhibitors (ARNIs). Valsartan, an angiotensin receptor blocker (ARB), works by blocking the effects of angiotensin II, which normally constricts blood vessels. Sacubitril, a neprilysin inhibitor, relaxes and widens blood vessels and increases the levels of beneficial natural peptides in the body, which reduce strain on the heart, fluid buildup, and blood pressure. Together, these actions make it easier for the heart to pump blood throughout the body and help the body retain less water.

What is the usual dosage for SACUVAL 200 TAB?

The dosage of SACUVAL 200 TAB is determined by your doctor based on your specific medical condition and how you respond to the medicine. The tablets should be swallowed whole with water, typically at the same time each day, and can be taken with or without food. Do not chew, crush, or break the tablet. It is important not to exceed the recommended dose.

What are the possible side effects of SACUVAL 200 TAB?

Common side effects can include cough, dizziness, nausea, diarrhea, weakness or fatigue, low blood pressure (hypotension), and elevated potassium levels in the blood (hyperkalemia). Some individuals may also experience kidney function abnormalities. Serious side effects, though less common, can include angioedema (swelling of the face, lips, tongue, and throat, causing difficulty breathing) and severe allergic reactions. If you experience persistent or severe side effects, you should consult your doctor.

Is SACUVAL 200 TAB safe during pregnancy or breastfeeding?

SACUVAL 200 TAB is generally not recommended during pregnancy as there is definite evidence of risk to the developing baby, potentially causing injury or endangering its life. If you become pregnant while taking this medicine, stop immediately and contact your doctor. Similarly, it is probably unsafe and not recommended for use while breastfeeding; consult your doctor for safer alternatives.

Can SACUVAL 200 TAB be taken with other medications?

It is crucial to inform your doctor about all medications you are currently taking, including over-the-counter drugs, supplements, and herbal products. SACUVAL 200 TAB should not be taken with ACE inhibitors (e.g., captopril or enalapril), and a 36-hour washout period is required before or after taking an ACE inhibitor to avoid increased risk of side effects like angioedema. Caution is also advised with potassium supplements, salt substitutes, painkillers, other heart or blood pressure medications (especially those containing aliskiren), and lithium. Potassium-sparing diuretics may increase serum potassium when taken with SACUVAL 200 TAB.

What precautions should be taken while on SACUVAL 200 TAB?

Before taking SACUVAL 200 TAB, inform your doctor if you have kidney or liver problems, low blood pressure, dehydration, diabetes, or a history of angioedema. Dose adjustments may be necessary for kidney or liver disease, and the medicine is contraindicated in severe liver disease. Due to the risk of dizziness, particularly when standing up, it's advised to rise slowly from a sitting or lying position. Avoid alcohol consumption as it may increase dizziness. Also, avoid potassium-rich foods like bananas and broccoli, and potassium supplements, as this medicine can increase potassium levels in your blood; regular monitoring of potassium levels is recommended. Regular monitoring of blood pressure and kidney function is also advised. Do not drive or operate heavy machinery if you experience dizziness.

What happens if a dose of SACUVAL 200 TAB is missed?

If you miss a dose of SACUVAL 200 TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should SACUVAL 200 TAB be stored?

SACUVAL 200 TAB should be stored in a cool and dry place, protected from light and moisture, typically below 30°C (or below 25°C). Keep the medicine out of the sight and reach of children and pets. Do not use the medicine after its expiry date.