Glimer M2

GLIMER M2 Tablet

Glimer M2 Tablet is an anti-diabetic medication used to manage type 2 diabetes mellitus. It combines two active ingredients to help control blood sugar levels when diet and exercise alone are insufficient.

• Name: Glimer M2 (Brand Name)
• Composition:
  • Glimepiride (2 mg)
  • Metformin Hydrochloride (500 mg)
• Uses:
  • Treatment of type 2 diabetes mellitus, especially in patients whose blood sugar levels are not adequately controlled by diet and exercise alone.
  • Helps to lower blood sugar levels by stimulating insulin secretion and improving insulin sensitivity.
  • Aids in reducing both fasting and post-meal blood glucose levels.
  • Contributes to the reduction of cardiovascular risks associated with diabetes.
  • Prevents diabetes-related complications such as kidney damage, eye problems, and nerve issues.
• Dosage and Administration:
  • Typically taken orally, with or just before the first main meal of the day (usually breakfast).
  • Swallow the tablet whole with a glass of water; do not chew, crush, or break it, as this can affect its extended-release properties.
  • Always follow the dosage and duration prescribed by a physician. The dose may vary based on individual factors and response to the medicine.
  • Regular monitoring of blood sugar levels is advised while on this medication.
• Side Effects:
  • Common: Stomach pain, nausea, vomiting, diarrhoea, headache, metallic taste, flatulence, and hypoglycemia (low blood sugar level).
  • Serious (rare): Lactic acidosis (accumulation of lactic acid in the body), characterized by deep or rapid breathing, persistent nausea, vomiting, and stomach pain. Seek immediate medical attention if these symptoms occur.
• Precautions:
  • Allergies: Do not take if allergic to Glimepiride, Metformin, or any other components of the medicine.
  • Pregnancy and Breastfeeding: Not recommended during pregnancy as it may harm the unborn baby. Avoid during breastfeeding as it may pass into breast milk and cause adverse effects in the baby.
  • Alcohol Consumption: Avoid excessive alcohol intake as it may increase the risk of lactic acidosis.
  • Medical Conditions: Inform your doctor if you have liver or kidney problems, severe infections, uncontrolled diabetes, type 1 diabetes mellitus, diabetic ketoacidosis, diabetic coma, or heart failure.
  • Driving and Operating Machinery: May decrease alertness; drive only if you are alert after taking the medication.
  • Drug Interactions: May interact with antibiotics (e.g., rifampicin, trimethoprim), calcium channel blockers (e.g., verapamil), antacids (e.g., cimetidine), HIV/AIDS drugs (e.g., dolutegravir), heart medicines (e.g., ranolazine), anticancer drugs, antifungals (e.g., fluconazole, miconazole), diuretics (e.g., acetazolamide), insulin, and anticonvulsants (e.g., phenytoin).
  • Diet: High-fibre foods can slow down the absorption of metformin, potentially altering the medicine's effectiveness.
• Storage:
  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of reach and sight of children.
  • Store at temperatures between 10ºC to 25ºC or below 30ºC.

GLIMER M2, a medication by ENTERO HEALTHCARE - CND DIV, is a combination of Glimepiride and Metformin used for managing Type 2 Diabetes Mellitus.

What is GLIMER M2 used for?

GLIMER M2 is primarily used to manage high blood sugar levels in adults with Type 2 diabetes mellitus when diet and exercise alone are insufficient. It helps improve glycemic control and can reduce the risk of diabetes-related complications such as nerve damage, kidney problems, and heart disease.

How does GLIMER M2 work?

GLIMER M2 combines two active ingredients: Glimepiride and Metformin. Glimepiride stimulates the pancreas to release more insulin, which helps lower blood sugar levels. Metformin works by reducing glucose production in the liver, decreasing glucose absorption from the intestines, and improving the body's sensitivity to insulin.

What is the usual dosage for GLIMER M2?

Typically, GLIMER M2 is taken once or twice daily with a meal, or as advised by your doctor. It should be swallowed whole with a glass of water and not crushed or chewed. Your doctor will determine the appropriate dosage, which may be adjusted over time based on your blood sugar levels.

What are the possible side effects of GLIMER M2?

Common side effects include hypoglycemia (low blood sugar), gastrointestinal disturbances such as nausea, vomiting, diarrhea, abdominal pain, headache, and taste disturbance. It's important to be aware of the signs of low blood sugar, like sweating, dizziness, headaches, and shaking.

Is GLIMER M2 safe during pregnancy or breastfeeding?

GLIMER M2 is generally not recommended during pregnancy, especially in the second and third trimesters, as animal studies have shown harmful effects on the developing baby. It is also advised to avoid breastfeeding while taking this medicine as it may be excreted in breastmilk and could cause adverse effects in the baby. Always consult your doctor for safer alternatives if you are pregnant or breastfeeding.

Can GLIMER M2 be taken with other medications?

GLIMER M2 can interact with various medications. Taking it with other antidiabetic drugs (e.g., insulin, other sulfonylureas) can increase the risk of hypoglycemia. Diuretics, corticosteroids, thyroid medications, and certain antibiotics or antifungals can also interact with GLIMER M2, potentially affecting its effectiveness or increasing side effects. Inform your physician about all medications you are taking.

What precautions should be taken while on GLIMER M2?

It is advisable to avoid alcohol consumption while taking GLIMER M2 as it can increase the risk of low blood sugar and a rare but serious condition called lactic acidosis. Regular monitoring of blood sugar levels and kidney function is recommended. Inform your doctor if you have liver or kidney problems, or if you are scheduled for surgery.

What happens if a dose of GLIMER M2 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

How should GLIMER M2 be stored?

GLIMER M2 should be stored in a cool and dry place, away from direct sunlight.