Monlevo Tablet

MONLEVO TABLET

Monlevo Tablet is a combination medication manufactured by FRANCO-INDIAN PHARMACEUTICALS PVT. LTD., primarily used for the relief and prevention of allergic conditions.

Composition Each Monlevo Tablet contains:

• Montelukast (10 mg): A leukotriene receptor antagonist that works by blocking chemical messengers called leukotrienes, which are responsible for inflammation and swelling in the nose and airways.
• Levocetirizine (5 mg): A non-sedative antihistamine that blocks the action of histamine, a substance in the body that causes allergic symptoms.

Uses Monlevo Tablet is prescribed for the management of various allergic and respiratory conditions, including:

• Allergic Rhinitis: Effective against seasonal and perennial allergic rhinitis, relieving symptoms such as sneezing, runny or stuffy nose, nasal itching, and watery or itchy eyes.
• Chronic Idiopathic Urticaria: Alleviates symptoms of chronic hives, including itching, redness, and swelling.
• Asthma-associated Rhinitis: Helps in reducing nasal inflammation and improving breathing in individuals with both allergic rhinitis and asthma, though it is not a rescue medication for acute asthma attacks.

Dosage and Administration The typical dosage for adults and adolescents aged 15 years and older is one tablet taken once daily, preferably in the evening. It can be taken with or without food. Tablets should be swallowed whole with water and not crushed, chewed, or broken. Adhere strictly to the doctor's prescribed dosage and duration of treatment.

Side Effects Common side effects may include:

• Abdominal pain, nausea, vomiting, diarrhea, indigestion
• Headache, dizziness, fatigue, sleepiness/drowsiness
• Dry mouth, sore throat, upper respiratory tract infection, fever, cough
• Skin rash, increased liver enzymes

More serious but less common side effects that require immediate medical attention include neuropsychiatric disorders (e.g., agitation, anxiety, depression, hallucinations, suicidal thoughts), severe allergic reactions (e.g., swelling of the face or throat, difficulty breathing), and liver dysfunction.

Precautions

• Do not take Monlevo Tablet if you are allergic to levocetirizine, montelukast, cetirizine, or any of its components.
• Contraindicated in patients with severe kidney impairment.
• Caution is advised for patients with liver problems.
• This medicine may cause dizziness and sleepiness; therefore, avoid driving or operating heavy machinery until you know how it affects you.
• Avoid alcohol consumption while taking Monlevo Tablet as it may enhance drowsiness.
• Inform your doctor about all existing medical conditions, especially asthma, epilepsy, or psychiatric illnesses, and any other medications, supplements, or herbal products being taken to prevent potential interactions.
• Consult a doctor if pregnant or breastfeeding, as components of the medicine may pass into breast milk.
• It is recommended to stop taking Monlevo Tablet at least three days before an allergy test, as it can affect test results.

Storage Store Monlevo Tablet in a cool and dry place, protected from direct sunlight and moisture, at a temperature below 30°C (or between 15-25°C). Keep it out of sight and reach of children.

MONLEVO TABLET by FRANCO-INDIAN PHARMACEUTICALS PVT. LTD. is a combination medicine primarily used to manage and prevent symptoms associated with various allergic conditions and respiratory issues like asthma. It contains two active ingredients: Montelukast and Levocetirizine.

Here are some frequently asked questions about MONLEVO TABLET:

What is MONLEVO TABLET used for?

MONLEVO TABLET is used to relieve and/or prevent symptoms of allergic rhinitis, which includes seasonal allergies (hay fever) and perennial (year-round) allergies. It helps alleviate symptoms such as runny nose, stuffy nose, sneezing, itching, swelling, congestion, and watery eyes. Additionally, it is used in the treatment of chronic idiopathic urticaria (hives) and to manage asthma symptoms by reducing inflammation in the airways, making breathing easier.

How does MONLEVO TABLET work?

MONLEVO TABLET works through a dual mechanism due to its two active components: Montelukast and Levocetirizine.

• Montelukast is a leukotriene receptor antagonist. It blocks the action of leukotrienes, which are natural chemicals in the body that cause inflammation in the airways and nasal passages, contributing to allergy and asthma symptoms. By blocking leukotrienes, it helps reduce inflammation and ease breathing.
• Levocetirizine is an antihistamine. It works by blocking the action of histamine, another natural substance released by the body during an allergic reaction, which causes symptoms like itching, sneezing, and runny nose. Together, these ingredients provide comprehensive relief by targeting different pathways involved in allergic responses.

What is the usual dosage for MONLEVO TABLET?

For adults and adolescents 15 years and older, the typical dose is one tablet (10mg Montelukast/5mg Levocetirizine) taken orally once daily, usually in the evening. It can be taken with or without food, but consistency in timing each day is recommended for optimal results. For children between 6 to 14 years, a different formulation or strength might be prescribed, so it is important to confirm the dosage with a physician. It is crucial to adhere strictly to your doctor's instructions regarding dosage and duration of treatment and not to stop the medication abruptly without consulting your doctor.

What are the possible side effects of MONLEVO TABLET?

Common side effects of MONLEVO TABLET may include headache, dizziness, drowsiness, fatigue, nausea, vomiting, diarrhea, abdominal pain, dry mouth, and upper respiratory tract infection. Less common but more serious side effects can include mood changes (such as anxiety, depression, agitation, or suicidal thoughts), sleep disturbances, blurred vision, palpitations, nosebleeds, and allergic reactions (like hives, itching, or difficulty breathing). If any side effects persist or worsen, or if you experience unusual or severe symptoms, contact your doctor immediately.

Is MONLEVO TABLET safe during pregnancy or breastfeeding?

Pregnancy: There is limited information about the effect of MONLEVO TABLET during pregnancy. It is generally recommended to avoid taking this medicine during pregnancy unless it is prescribed by your doctor, who will weigh the benefits against the potential risks. Always inform your doctor if you are pregnant or think you may be pregnant.

Breastfeeding: A component of MONLEVO TABLET passes into human breast milk and may cause drowsiness in the newborn baby. Therefore, it is generally recommended to avoid taking this medicine while breastfeeding unless specifically prescribed by your doctor. Inform your doctor if you are a breastfeeding mother.

Can it be taken with other medications?

MONLEVO TABLET can interact with other substances, potentially affecting its efficacy or increasing the risk of side effects. Common interactions include certain antibiotics, antifungals, and medications that depress the central nervous system (CNS depressants) such as barbiturates (e.g., phenobarbital), benzodiazepines (e.g., alprazolam), and sedatives. Montelukast, one of the active ingredients, may interact with medicines metabolized by the Cytochrome P-450 CYP2C8 enzyme (e.g., warfarin, rosiglitazone). Always inform your doctor about all other medicines you are taking, including prescription, over-the-counter drugs, and herbal supplements, to prevent adverse reactions.

What precautions should be taken?

• Driving and Operating Machinery: MONLEVO TABLET can cause dizziness, drowsiness, and fatigue. It is advised to be cautious while driving or operating any machinery until you know how the medicine affects you.
• Alcohol Consumption: Avoid or limit alcohol consumption during treatment as it may exacerbate drowsiness and other side effects.
• Pre-existing Medical Conditions: Inform your doctor if you have any pre-existing medical conditions, especially kidney or liver problems, psychiatric illnesses, or a genetic disorder called phenylketonuria.
• Acute Asthma Attacks: MONLEVO TABLET is not a rescue medication for acute asthma attacks. Always carry your prescribed rescue inhaler for such situations.
• Grapefruit Juice: Avoid consuming grapefruit juice as it may affect how the medication is absorbed.

What happens if a dose is missed?

If you miss a dose of MONLEVO TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should it be stored?

MONLEVO TABLET should be stored in a cool, dry place, typically below 30°C, and protected from light and moisture. Keep it out of the reach of children and pets. Always check the expiration date before taking the medicine.