Thyrox 125mcg (100 Tab)

THYROX 125 MCG (100 TAB) by MACLEODS PHARMACEUTICALS LTD.

• Name:

  • Brand Name: Thyrox 125 mcg
  • Common Name: Levothyroxine Sodium (Thyroxine)

• Composition:

  • Each tablet contains Thyroxine Sodium equivalent to 125 micrograms (mcg) of Levothyroxine.

• Uses: Thyrox 125 mcg Tablet is primarily used to treat conditions associated with an underactive thyroid gland. It works by replacing the thyroid hormone that the body naturally produces.

  • Hypothyroidism: Manages symptoms of low thyroid hormone levels such as fatigue, weight gain, and depression.
  • Goitre Management: Helps reduce the size of an enlarged thyroid gland.
  • Thyroid Hormone Replacement: Used after surgical removal of the thyroid gland.
  • Thyroid Cancer: May be used to suppress thyroid-stimulating hormone (TSH) in certain types of thyroid cancer.

• Dosage and Administration:

  • Thyrox 125 mcg Tablet should be taken orally once daily on an empty stomach, typically 30-60 minutes before breakfast, with a full glass of water.
  • It is crucial to take the medication at the same time each day for consistent results.
  • Do not chew, crush, or split the tablet; swallow it whole.
  • The dosage is determined and adjusted by a doctor based on individual thyroid hormone levels, age, weight, and response to treatment.

• Side Effects: Many side effects are typically due to a higher dose than needed and may resolve with dose adjustment.

  • Common Side Effects: Shaking and trembling (tremors), diarrhea, abdominal cramps, nervousness, sleeplessness (insomnia), excessive sweating, heat intolerance, weight loss, increased appetite, rapid or irregular heartbeat (palpitations), changes in menstrual cycle, and temporary hair loss (especially in children).
  • Serious Side Effects (Seek medical attention if persistent or severe): Chest pain, thyrotoxic crisis (extremely high levels of thyroid hormones causing adverse effects).

• Precautions:

  • Contraindications: Avoid if allergic to Thyroxine, or in cases of untreated hyperthyroidism, thyrotoxicosis, severe heart conditions (e.g., acute myocardial infarction), or adrenal insufficiency.
  • Medical Conditions: Use with caution in patients with heart disease (may worsen angina or irregular heartbeat), diabetes (may affect blood glucose levels requiring medication adjustment), or thyroid nodules.
  • Bone Health: Long-term use, particularly in postmenopausal women, may reduce bone mineral density and increase fracture risk.
  • Drug Interactions: Inform your doctor about all medicines, including supplements and herbal preparations. Antacids, calcium or iron supplements, multivitamins, cholestyramine, colesevelam, colestipol, sevelamer, sodium polystyrene sulfonate, lanthanum, and sucralfate should be taken at least 4 hours apart from Thyrox 125 mcg Tablet as they can interfere with absorption.
  • Food Interactions: Grapefruit juice, soybean flour, fiber-rich foods, walnuts, and cottonseed meal may lower the effect of this medication and should be avoided when taking it.
  • Pregnancy and Breastfeeding: Generally considered safe when prescribed during pregnancy and breastfeeding, but dosage adjustments may be necessary.
  • Not for Weight Loss: Thyrox 125 mcg Tablet should not be used solely for weight loss.

• Storage:

  • Store in a cool and dry place, preferably below 25°C or 30°C.
  • Protect from sunlight.
  • Keep out of sight and reach of children.

THYROX 125MCG (100 TAB) - Frequently Asked Questions

What is THYROX 125MCG used for?

THYROX 125MCG is primarily used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones. It also serves as replacement therapy after thyroid gland removal, helps manage enlarged thyroid glands (goitre), and can be used in treating certain types of thyroid cancer by suppressing thyroid-stimulating hormone (TSH).

How does THYROX 125MCG work?

THYROX 125MCG contains Thyroxine (levothyroxine), a synthetic version of the naturally occurring thyroid hormone (T4). It works by replacing the missing thyroid hormones in the body, which helps to restore normal energy levels and metabolism. It affects nearly every organ in the body, regulating processes like heart function and digestion. In cases of thyroid cancer, it also helps suppress TSH, which can slow down the growth of TSH-dependent thyroid tumors.

What is the usual dosage for THYROX 125MCG?

The dosage of THYROX 125MCG is determined by your doctor based on your thyroid hormone levels, age, weight, and response to treatment. For adults, the usual starting dose is often 50 to 100 micrograms daily. It should be taken once daily in the morning on an empty stomach, preferably 30 to 60 minutes before any food or other medications.

What are the possible side effects of THYROX 125MCG?

Most side effects are temporary and often occur if the dose is higher than needed. Common side effects can include shaking and trembling of arms and feet, diarrhea, nervousness, irritability, sleeplessness, excessive sweating, heat intolerance, weight loss, increased appetite, headache, and a rapid or irregular heartbeat. Children may experience temporary hair loss, which is usually reversible. If side effects persist or are severe, consult your doctor.

Is THYROX 125MCG safe during pregnancy or breastfeeding?

Yes, THYROX 125MCG is generally considered safe for use during pregnancy and while breastfeeding. It is important to continue taking it throughout pregnancy as uncontrolled thyroid hormone levels can pose risks to both the mother and baby. Your doctor may need to adjust your dose during pregnancy and monitor your thyroid levels regularly. During breastfeeding, only tiny amounts pass into breast milk, which are usually too small to affect the baby.

Can THYROX 125MCG be taken with other medications?

THYROX 125MCG can interact with several other medications and certain foods. It is important to inform your doctor about all medicines, dietary supplements, and herbal preparations you are taking. Interactions can occur with antacids (especially those containing calcium, magnesium, or aluminum), calcium and iron supplements, proton pump inhibitors (PPIs), and bile acid sequestrants. Foods like grapefruit, soybean flour, fiber-rich foods, and walnuts can also interfere with its absorption. It is recommended to take THYROX 125MCG at least 4 hours apart from these interacting substances.

What precautions should be taken while using THYROX 125MCG?

Do not use THYROX 125MCG to treat obesity or for weight loss. Exercise caution and inform your doctor if you have heart conditions (such as angina or irregular heartbeat), hyperthyroidism, thyrotoxicosis, adrenal insufficiency, or diabetes, as dose adjustments or close monitoring may be required. Postmenopausal women and those with osteoporosis should be monitored for bone mineral density, as long-term use can sometimes reduce it. Regular monitoring of thyroid hormone levels is essential to ensure the correct dosage.

What happens if a dose of THYROX 125MCG is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. Due to the long half-life of levothyroxine (about 7 days), a single missed dose typically does not significantly affect your thyroid levels.

How should THYROX 125MCG be stored?

THYROX 125MCG should be stored below 25°C, in its original bottle, kept tightly closed, and protected from light, heat, and moisture. Some recommendations suggest refrigeration to maintain potency. Do not store it in the bathroom, near a sink, in the car, or on windowsills. Keep it out of reach of children.