Supirocin Ointment

SUPIROCIN OINTMENT by GLENMARK LABORATORIES

Supirocin Ointment is a topical antibiotic medication manufactured by Glenmark Laboratories, designed for external use to treat various bacterial skin infections.

• Name:

  • Brand Name: Supirocin Ointment
  • Common Name: Mupirocin Ointment

• Composition:

  • Active Ingredient: Mupirocin (2% w/w)
  • Mupirocin is an antibiotic that works by inhibiting bacterial protein synthesis, thereby stopping the growth and spread of infection-causing bacteria. It is effective against bacteria such as Staphylococcus aureus and Streptococcus pyogenes, and also against Gram-negative organisms like Escherichia coli and Haemophilus influenza.

• Uses: Supirocin Ointment is prescribed for the topical treatment of primary and secondary bacterial skin infections. These include:

  • Impetigo (red sores)
  • Folliculitis (infected hair follicles)
  • Recurring boils
  • Infected cuts, wounds, and abrasions
  • Post-surgical care to reduce infection risk in stitched areas.
  • Relief of eczema and dermatitis symptoms by reducing irritation and preventing bacterial infections.

• Dosage and Administration:

  • For dermatologic use only.
  • A small amount of Supirocin Ointment should be applied to cover the affected area two to three times daily.
  • The treated area may be covered with a sterile gauze dressing if desired.
  • Treatment duration usually does not exceed 10 days.
  • Always wash hands before and after application.
  • Complete the full course of treatment as prescribed, even if symptoms improve.

• Side Effects:

  • Common Side Effects: Burning sensation, itching, redness, stinging, dryness, and pain at the application site. These are usually temporary.
  • Serious Side Effects (Rare):
    • Severe allergic reactions such as rash, hives, swelling, wheezing, swelling of the lips/mouth, difficulty breathing, or fainting.
    • Inflammation of the colon (pseudomembranous colitis), which can cause diarrhea (often with blood and mucus), stomach pain, and fever.
    • If any serious side effects or worsening of condition occur, discontinue use and seek immediate medical attention.

• Precautions:

  • Do not use if allergic to mupirocin or any other ingredients.
  • For external use only; avoid contact with eyes, nose, mouth, or other mucosal surfaces. If contact occurs, rinse thoroughly with water.
  • Not suitable for application to broken skin, extensive open wounds, or burns, especially in patients with moderate to severe renal impairment, due to the presence of polyethylene glycol in some formulations which can be absorbed.
  • Avoid using on skin areas near cannulae (tubes inserted for fluid delivery or removal).
  • Prolonged or irregular use can lead to the overgrowth of non-susceptible bacteria or fungi and antibiotic resistance.
  • Should be used with caution in children less than 2 months of age, and generally not recommended for infants younger than 2 months.
  • Do not mix with other topical preparations, as they may prevent Supirocin from working effectively.
  • Consult a doctor if pregnant or breastfeeding. Systemic absorption is very low, making interactions with systemic drugs unlikely.

• Storage:

  • Store at or below 25°C (ideally between 15°C and 25°C).
  • Do not freeze.
  • Keep in a cool, dry place, away from moisture, heat, and direct sunlight.
  • Keep the tube tightly shut when not in use.
  • Keep out of sight and reach of children.

Supirocin Ointment, manufactured by Glenmark Laboratories, is a topical antibiotic commonly prescribed for various bacterial skin infections. Its active ingredient, mupirocin, works by preventing bacteria from producing essential proteins, thus inhibiting their growth and eliminating the infection.

Here are some frequently asked questions about Supirocin Ointment:

What is Supirocin Ointment used for?

Supirocin Ointment is a topical antibiotic primarily used to treat bacterial skin infections such as impetigo (red sores), folliculitis (infected hair follicles), and furunculosis (boils). It is also effective for treating infected minor cuts, wounds, abrasions, and sutured wounds, as well as for preventing infections in minor skin injuries. This ointment is effective against specific bacteria like Staphylococcus aureus (including some methicillin-resistant strains) and Streptococcus pyogenes. It is not effective against fungal or viral infections.

How does Supirocin Ointment work?

Supirocin Ointment works by stopping the growth of infection-causing bacteria on your skin. Its active ingredient, mupirocin, specifically binds to an enzyme in bacteria called isoleucyl transfer-RNA synthetase. This action prevents the bacteria from synthesizing essential proteins they need to survive and multiply, ultimately killing them.

What is the usual dosage for Supirocin Ointment?

The usual dosage involves applying a small, thin layer of Supirocin Ointment to the affected skin area two to three times daily. Treatment typically lasts for 5 to 10 days, or as directed by your doctor. The treated area may be covered with a sterile gauze dressing if desired. It is crucial to complete the entire prescribed course of treatment, even if your symptoms improve, to prevent the infection from returning and to avoid the development of antibiotic resistance.

What are the possible side effects of Supirocin Ointment?

Common side effects at the application site include burning, stinging, itching, redness, dryness, and pain. Less frequently reported side effects can include rash, erythema, tenderness, swelling, and contact dermatitis. In rare cases, severe allergic reactions such as rash, hives, swelling of the face, lips, tongue, or throat, shortness of breath, wheezing, or fainting can occur. If you experience severe or persistent side effects or any signs of an allergic reaction, you should stop using the ointment and contact your doctor immediately.

Is Supirocin Ointment safe during pregnancy or breastfeeding?

During Pregnancy: Supirocin Ointment is generally considered safe for use during pregnancy if clearly needed and prescribed by a doctor. Animal studies have indicated low or no adverse effects on the developing baby, though human studies are limited. It is classified as a Pregnancy Category B drug.

During Breastfeeding: Caution is advised when using Supirocin Ointment while breastfeeding, as it is not known whether the medication passes into breast milk. If the ointment is applied to the breast or nipple area, ensure it is thoroughly washed off before nursing to prevent accidental ingestion by the infant.

Can Supirocin Ointment be taken with other medications?

Due to its minimal absorption through the skin, Supirocin Ointment has no reported interactions with systemic (oral) medications. However, it is not recommended to mix Supirocin Ointment with other topical creams, ointments, or lotions on the same treated area. Doing so may dilute the medication, reduce its effectiveness, and potentially affect its stability. Always inform your doctor or pharmacist about any other topical or systemic medications you are using.

What precautions should be taken while using Supirocin Ointment?

Supirocin Ointment is for external use only. Avoid getting it in your eyes, nose, or mouth. If accidental contact occurs, rinse the area thoroughly with water. Do not apply the ointment to large areas of broken skin, extensive open wounds, or burns, especially if you have moderate to severe kidney problems, as a component of the ointment (polyethylene glycol) could be absorbed. Discontinue use if you experience irritation, severe itching, or any signs of an allergic reaction. Complete the full course of treatment as prescribed, even if symptoms improve, to prevent antibiotic resistance. Prolonged use may lead to the overgrowth of non-susceptible organisms, including fungi. Supirocin Ointment is not recommended for infants younger than 2 months of age. Also, avoid applying it to skin areas around tubes inserted into the body (cannulae).

What happens if a dose of Supirocin Ointment is missed?

If you miss a dose of Supirocin Ointment, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply extra ointment or a double dose to compensate for the missed one.

How should Supirocin Ointment be stored?

Supirocin Ointment should be stored at room temperature, ideally between 15°C and 25°C, or below 25°C/30°C, in a cool and dry place. Protect it from direct sunlight, heat, and moisture. Do not freeze the ointment. Always keep the tube tightly closed when not in use and store it out of the sight and reach of children and pets.