Azulix Dm 2/10/500 Tab

AZULIX DM 2/10/500 Tablet

AZULIX DM 2/10/500 is a prescription medicine manufactured by Torrent Pharma, used for the management of Type 2 Diabetes Mellitus.

• Composition

  • Dapagliflozin: 10 mg
  • Glimepiride: 2 mg
  • Metformin Hydrochloride (Extended Release): 500 mg

• Uses AZULIX DM 2/10/500 is indicated as an adjunct to diet and exercise to improve glycemic control in adult patients with Type 2 Diabetes Mellitus. It works by enhancing insulin sensitivity, stimulating insulin secretion, and promoting glucose excretion in the urine, thereby aiding in the reduction of blood sugar levels and improving blood sugar control.

• Dosage and Administration Take AZULIX DM 2/10/500 orally with meals, as directed by your healthcare provider. It is typically taken once or twice daily, and tablets should be swallowed whole. Do not self-adjust the dosage, and it is crucial to follow a healthy diet and exercise regimen while on this medication.

• Side Effects

  • Common Side Effects: Hypoglycemia (low blood sugar) with symptoms like sweating, shakiness, confusion, and hunger, nausea, vomiting, diarrhea, headache, dizziness, increased urination, and genital fungal infections.
  • Serious Side Effects: Lactic acidosis (a rare but severe condition), severe urinary tract infections, and allergic reactions. Seek immediate medical attention if these occur.

• Precautions

  • Pregnancy and Breastfeeding: Generally not recommended during pregnancy and caution is advised during breastfeeding. Consult your doctor for alternative treatment options.
  • Alcohol Consumption: Limit or avoid alcohol as it may increase the risk of hypoglycemia and lactic acidosis.
  • Kidney and Liver Issues: Use with caution in patients with kidney or liver problems. It is contraindicated in severe kidney problems (GFR < 30 mL/min).
  • Elderly Patients: Special caution is required in the elderly as they may be more prone to hypoglycemia.
  • Driving and Operating Machinery: This medicine may cause dizziness or drowsiness due to fluctuations in blood sugar. Avoid driving or operating machinery until you know how it affects you.
  • Drug Interactions: AZULIX DM 2/10/500 may interact with certain medications like insulin, ACE inhibitors, corticosteroids, sulfonylureas, and beta-blockers. Inform your healthcare provider about all medicines you are taking.
  • Hypersensitivity: Contraindicated in patients with hypersensitivity to the active substances or any of the excipients.

• Storage Store AZULIX DM 2/10/500 at room temperature (20-25°C or below 30°C). Protect from moisture and light, and keep it in the original packaging, out of the reach of children.

Here are some frequently asked questions about AZULIX DM 2/10/500 TAB:

What is AZULIX DM 2/10/500 TAB used for?

AZULIX DM 2/10/500 TAB is a fixed-dose combination medicine used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It is typically prescribed when diet and exercise alone, or dual therapy, are not sufficient to control blood sugar. This medication aims to improve glycemic control, reduce blood sugar levels, and help prevent serious complications of diabetes, such as kidney damage, vision problems, and nerve issues.

How does AZULIX DM 2/10/500 TAB work?

This medicine combines three active ingredients: Metformin (500mg), Glimepiride (2mg), and Dapagliflozin (10mg), each working through different mechanisms to control blood sugar. Metformin reduces glucose production in the liver and improves the body's sensitivity to insulin. Glimepiride stimulates the pancreas to release more insulin. Dapagliflozin works by blocking specific proteins in the kidneys (SGLT2 receptors), which helps the body remove excess sugar through urine.

What is the usual dosage for AZULIX DM 2/10/500 TAB?

AZULIX DM 2/10/500 TAB is typically taken orally with meals, once or twice daily, as directed by your healthcare provider. It is important to swallow the tablet whole and not crush, break, or chew it. Your doctor will determine the specific dosage based on your blood glucose levels and response to treatment, and you should never adjust the dose without consulting them.

What are the possible side effects of AZULIX DM 2/10/500 TAB?

Common side effects may include hypoglycemia (low blood sugar) with symptoms like sweating, shakiness, confusion, and hunger, as well as nausea, vomiting, diarrhea, increased urination, headache, and dizziness. Some individuals may also experience genital fungal infections. More serious but rare side effects include lactic acidosis, which requires immediate medical attention.

Is AZULIX DM 2/10/500 TAB safe during pregnancy or breastfeeding?

AZULIX DM 2/10/500 TAB is generally not recommended during pregnancy, and you should consult your doctor for alternative treatment options if you are pregnant or planning to become pregnant. The safety of this combination during breastfeeding is not firmly established, so it's advisable to consult your healthcare provider before using it while breastfeeding.

Can AZULIX DM 2/10/500 TAB be taken with other medications?

This medicine may interact with certain other medications, including insulin, ACE inhibitors, corticosteroids, diuretics (like furosemide or hydrochlorothiazide), other insulin secretagogues (such as gliclazide or glipizide), and beta-blockers. It is crucial to inform your healthcare provider about all medicines, supplements, and herbal products you are currently taking to avoid potential drug interactions.

What precautions should be taken while taking AZULIX DM 2/10/500 TAB?

It is important to limit or avoid alcohol consumption while taking this medicine, as it can increase the risk of hypoglycemia and lactic acidosis. Special caution is advised for elderly patients, as they may be more susceptible to hypoglycemia. If you have kidney or liver problems, heart failure, or a history of diabetic ketoacidosis, your doctor may need to adjust the dosage or recommend an alternative. Regular monitoring of blood sugar levels, kidney function, and liver function is recommended. Due to potential dizziness or drowsiness, it is advised to avoid driving or operating machinery until you understand how the medicine affects you. Maintaining good hygiene can help prevent genital fungal infections, and staying well-hydrated is also important.

What happens if a dose of AZULIX DM 2/10/500 TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should AZULIX DM 2/10/500 TAB be stored?

Store AZULIX DM 2/10/500 TAB at room temperature, typically between 20-25°C or below 30°C. Keep it protected from moisture and light, and always store it in its original packaging. Ensure the medicine is kept out of the sight and reach of children.