Peg Sr M 75 Mg (10 Tab)

Peg SR M 75 MG Tablet

Peg SR M 75 MG Tablet is a combination medication primarily used for the management of neuropathic pain, which is pain caused by damaged nerves. It is manufactured by IPCA LABORATORIES LTD.

• Composition

  • Active Ingredients: Each sustained-release tablet contains Pregabalin 75 mg and Methylcobalamin 1500 mcg.
  • Mechanism of Action: Pregabalin, an alpha-2 delta ligand, works by modulating calcium channel activity in nerve cells, thereby decreasing the transmission of pain signals through damaged nerves and the brain. Methylcobalamin, a form of Vitamin B12, helps in the production of myelin, a substance that protects nerve fibers and aids in the regeneration and repair of damaged nerve cells.

• Uses Peg SR M 75 MG Tablet is prescribed for the treatment of nerve-related pain (neuropathic pain) in adults. This type of pain can result from conditions such as diabetes, shingles (postherpetic neuralgia), spinal cord injury, or other nerve damage. It helps to reduce pain and associated symptoms like mood changes, sleep problems, and tiredness.

• Dosage and Administration This medicine should be taken as directed by a healthcare professional, in the prescribed doses and for the recommended duration. It is usually advised to take it at the same time each day, with or without food, preferably at bedtime, to maintain consistent levels in the body. The tablet should be swallowed whole with water and not crushed or chewed. It is crucial not to stop the medication abruptly, as the doctor will gradually decrease the dose to prevent withdrawal symptoms.

• Side Effects Common side effects may include:

  • Dizziness
  • Drowsiness/Sleepiness
  • Blurred vision
  • Dry mouth
  • Constipation
  • Weight gain
  • Headache
  • Nausea, Vomiting, Diarrhea, or Flatulence
  • Increased appetite Serious side effects, though rare, can include severe allergic reactions (skin rash, itching, swelling of the face, lips, throat, or difficulty breathing) and mood changes, including suicidal thoughts. Consult a doctor if any side effects worsen or persist.

• Precautions

  • Pregnancy and Breastfeeding: It is generally advised not to take this medicine during pregnancy due to limited safety data; effective contraception is recommended for women of childbearing age. It is probably unsafe during breastfeeding, as the drug may pass into breast milk.
  • Alcohol: Avoid alcohol consumption during treatment as it may increase side effects such as dizziness and drowsiness.
  • Driving and Machinery: Peg SR M 75 MG Tablet can cause dizziness, sleepiness, or blurred vision, which may impair the ability to drive or operate machinery.
  • Medical Conditions: Use with caution in patients with existing medical conditions such as liver or kidney problems, epilepsy, heart issues, or low vitamin B12 levels.
  • Discontinuation: Do not stop taking the medicine suddenly without consulting a doctor, as it can lead to withdrawal symptoms.
  • Children: This medicine is not recommended for individuals under 18 years of age.

• Storage Store Peg SR M 75 MG Tablet in a cool, dry place, preferably below 30°C. Protect it from light and moisture. Keep it out of sight and reach of children.

What is PEG SR M 75 MG used for?

PEG SR M 75 MG is a combination medicine primarily used to relieve neuropathic pain in adults. This type of pain is caused by nerve damage due to conditions such as diabetic neuropathy, shingles (post-herpetic neuralgia), spinal cord injury, or fibromyalgia. The medicine may also be used as an add-on therapy for certain types of seizures (fits) and sometimes for anxiety.

How does PEG SR M 75 MG work?

This medicine combines Pregabalin and Methylcobalamin. Pregabalin works by calming damaged or overactive nerves in the brain and spinal cord, reducing the transmission of pain signals by modulating calcium channel activity. Methylcobalamin, an active form of Vitamin B12, is crucial for a healthy nervous system. It helps in repairing damaged nerves by aiding in the formation of the myelin sheath, which protects and insulates nerve fibers, and also contributes to pain relief.

What is the usual dosage for PEG SR M 75 MG?

PEG SR M 75 MG is a sustained-release (SR) formulation containing 75 mg of Pregabalin and 1500 mcg of Methylcobalamin. The exact dose and duration of treatment will be determined by your doctor, depending on your condition and response to the medicine. It should be taken as directed by your healthcare provider, usually swallowed whole with water, and can be taken with or without food. Your doctor may start with a lower dose and gradually increase it.

What are the possible side effects of PEG SR M 75 MG?

Common side effects can include dizziness, sleepiness or drowsiness, blurred vision, dry mouth, weight gain, swelling of your hands or feet (peripheral edema), headache, and difficulty concentrating. These side effects are usually mild and often improve over time.

More serious but less common side effects can include severe allergic reactions (such as rash, hives, swelling of the face, lips, tongue, or throat, and trouble breathing), unusual changes in mood or behavior, new or worsened depression, thoughts of self-harm or suicide, and respiratory depression (slow or shallow breathing), especially when taken with other central nervous system depressants. Contact your doctor immediately if you experience any serious side effects.

Is PEG SR M 75 MG safe during pregnancy or breastfeeding?

Pregnancy: If you are pregnant or planning to become pregnant, you should talk to your doctor before taking PEG SR M 75 MG. Caution is advised, and it is generally prescribed only if the potential benefits outweigh the risks. Suddenly stopping this medication during pregnancy can be dangerous.

Breastfeeding: Small amounts of Pregabalin, a component of this medicine, can pass into breast milk. While some limited data suggest it may be used with caution, especially for older infants, an alternative drug might be preferred, particularly for newborns or preterm infants. Infants should be monitored for adverse effects such as excessive sleepiness, poor feeding, or slowed breathing. Some sources advise against breastfeeding due to a potential, though unconfirmed, risk of tumorigenicity identified in animal studies. Always consult your healthcare provider to discuss the best approach for you and your baby.

Can PEG SR M 75 MG be taken with other medications?

Taking PEG SR M 75 MG with other medications that can cause drowsiness or slow down the central nervous system, such as opioids, benzodiazepines, muscle relaxants, antihistamines, or alcohol, can increase the risk of severe dizziness, sleepiness, and serious breathing problems. It may also interact with certain diabetes medications (like rosiglitazone or pioglitazone), potentially causing increased weight gain or swelling, and some blood pressure medications (e.g., captopril, enalapril, lisinopril), which could lead to swelling and hives. Always inform your doctor or pharmacist about all other medicines, supplements, and herbal products you are taking.

What precautions should be taken while taking PEG SR M 75 MG?

Due to potential dizziness and drowsiness, do not drive, operate machinery, or perform tasks requiring alertness until you understand how this medicine affects you. Alcohol should be avoided as it can increase these side effects. Inform your doctor if you have kidney or heart problems, a history of drug or alcohol misuse, depression, or other mental health conditions, as precautions or dose adjustments may be necessary. Do not stop taking PEG SR M 75 MG suddenly, as this can lead to withdrawal symptoms or worsen your underlying condition; your doctor will guide you on how to gradually reduce the dose.

What happens if a dose of PEG SR M 75 MG is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this could lead to increased side effects.

How should PEG SR M 75 MG be stored?

PEG SR M 75 MG should be stored at room temperature, typically between 15°C to 30°C (59°F to 86°F), away from moisture, heat, and direct sunlight. Keep the medicine in its original packaging and out of the reach of children and pets.