Nebi Am Tablet

NEBI AM TABLET by ARISTO PHARMACEUTICALS PVT LTD

Name

Brand Name: NEBI AM TABLET

Composition

NEBI AM TABLET contains two active ingredients:

• Nebivolol (5 mg): A beta-blocker that slows down the heart rate, reduces blood pressure, and decreases strain on the heart by blocking certain chemicals in the body and widening blood vessels.
• Amlodipine (5 mg): A calcium channel blocker that relaxes the smooth muscles in blood vessel walls, widening them to improve blood flow and reduce blood pressure.

Uses

NEBI AM TABLET is prescribed for the management of:

• Hypertension (High Blood Pressure): It effectively lowers elevated blood pressure levels.
• Heart-related complications: It helps reduce the strain on the heart, improves its efficiency in pumping blood, and enhances overall cardiovascular health.
• Combination therapy: It is used when a single medication containing either amlodipine or nebivolol is insufficient to control blood pressure.
• It can also be used to manage angina (chest pain) and heart failure.

Dosage and Administration

• NEBI AM TABLET should be taken as advised by your physician, typically once daily.
• The tablet should be swallowed whole with water and should not be chewed, crushed, or broken.
• It can be taken with or without food, but it is recommended to take it at the same time each day to maintain consistent blood levels and ensure effectiveness.
• Do not discontinue the medication suddenly without consulting your doctor, as abrupt withdrawal can worsen your condition.

Side Effects

Common Side Effects:

• Headache
• Fatigue/Tiredness
• Dizziness
• Nausea
• Peripheral oedema (swelling in ankles and feet)
• Bradycardia (slower-than-normal heart rate)
• Constipation

Serious Side Effects (seek immediate medical attention):

• Signs of allergic reactions (skin rash, swelling of face, lips, mouth, or throat leading to difficulty in breathing or swallowing)
• Severe skin reactions (blistering and peeling of skin)
• Severe chest pain or shortness of breath (signs of heart attack)
• Inflammation of the pancreas (severe stomach pain radiating to the back)

Precautions

• Allergies: Do not use if allergic to Amlodipine, Nebivolol, or any other components of the tablet.
• Liver/Kidney Conditions: Use with caution in patients with liver or kidney impairment; dose adjustment may be necessary.
• Heart Conditions: Not recommended for patients with severe heart problems like severe bradycardia, heart block greater than first-degree, or cardiogenic shock. Use with caution in those with coronary artery disease.
• Respiratory Diseases: Patients with bronchospastic diseases (e.g., asthma, COPD) should use with caution as it may worsen the condition.
• Pregnancy and Breastfeeding: Consult a doctor before use; not generally recommended unless benefits outweigh risks.
• Alcohol: Limit alcohol consumption as it may increase dizziness and drowsiness.
• Grapefruit Juice: Avoid grapefruit juice as it can further decrease blood pressure.
• Driving and Using Machines: May cause dizziness, so avoid activities requiring mental focus until you understand how the medicine affects you.
• Diabetes: Use with caution as it may mask symptoms of low blood sugar.
• Regular Monitoring: Regular monitoring of blood pressure, kidney function, blood sugar, and electrolyte levels may be advised.

Storage

• Store in a cool and dry place, away from direct sunlight.
• Keep out of sight and reach of children.
• Typically stored at room temperature between 10ºC to 25ºC or below 30ºC.
• Protect from light and heat.

Here are frequently asked questions about NEBI AM TABLET by ARISTO PHARMACEUTICALS PVT LTD:

What is NEBI AM TABLET used for?

NEBI AM TABLET is primarily used to manage hypertension (high blood pressure). It can also be used to manage angina (chest pain) and heart failure. This medication helps to lower blood pressure, reduce strain on the heart, and decrease the risk of cardiovascular complications such as heart attack and stroke.

How does NEBI AM TABLET work?

NEBI AM TABLET is a combination medicine containing Amlodipine and Nebivolol. Amlodipine is a calcium channel blocker that works by relaxing and widening blood vessels, which improves blood flow. Nebivolol is a beta-blocker that slows the heart rate and reduces the force of the heart's contractions. It also helps to widen blood vessels by stimulating nitric oxide release. Together, these actions lower blood pressure and reduce the heart's workload.

What is the usual dosage of NEBI AM TABLET?

The usual dosage for NEBI AM TABLET typically starts at 5mg/5mg once daily for hypertension, but this can vary depending on the individual's condition, age, and response to treatment. It should be swallowed whole with water, preferably at the same time each day, and can be taken with or without food. Do not crush or chew the tablet. Your doctor will determine the correct dose and duration of treatment.

What are the possible side effects of NEBI AM TABLET?

Common side effects include swelling of the ankles or other body parts (peripheral edema), headache, dizziness, sleepiness, fatigue, a racing heartbeat (palpitations), indigestion, constipation, nausea, tingling sensations, muscle cramps, and a slow heart rate (bradycardia). More serious but less common side effects can include signs of allergic reactions (like skin rash, swelling of the face, lips, mouth, or throat), severe skin reactions, chest pain or shortness of breath (which could indicate a heart attack), or inflammation of the pancreas. If any side effects are persistent or severe, contact your doctor.

Is NEBI AM TABLET safe during pregnancy or breastfeeding?

NEBI AM TABLET is generally not recommended for use during pregnancy or breastfeeding unless considered absolutely necessary by a physician. It is crucial to consult your doctor before taking this medicine if you are pregnant, planning to conceive, or breastfeeding.

Can NEBI AM TABLET be taken with other medications?

NEBI AM TABLET can interact with several other medications. It is important to inform your doctor about all medicines you are currently taking, including over-the-counter drugs and herbal supplements. Specific interactions can occur with other blood pressure-lowering medications (e.g., verapamil, diltiazem, clonidine, ACE inhibitors, angiotensin receptor blockers), CYP2D6 enzyme inhibitors (like quinidine, fluoxetine, and paroxetine), digitalis glycosides, and insulin. Additionally, avoid consuming grapefruit or grapefruit juice while on this medication, as it can increase the levels of amlodipine in your blood and potentially lead to increased side effects.

What precautions should be taken while using NEBI AM TABLET?

Before taking NEBI AM TABLET, inform your doctor if you have any liver or kidney problems, severe heart conditions (such as heart failure, slow heartbeat, or heart block), asthma, diabetes, thyroid problems, poor blood circulation (e.g., Raynaud's disease), psoriasis, glaucoma, hyperlipidaemia, Myasthenia Gravis, or pheochromocytoma. You should also avoid alcohol consumption as it can increase dizziness and drowsiness. Do not drive or operate heavy machinery if you experience dizziness or fatigue. It is vital not to stop taking this medication abruptly, as sudden discontinuation can worsen your condition. Regular monitoring of blood pressure, kidney function, blood sugar levels, and electrolytes may be necessary during treatment.

What happens if a dose of NEBI AM TABLET is missed?

If you miss a dose of NEBI AM TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should NEBI AM TABLET be stored?

NEBI AM TABLET should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of sight and reach of children. The recommended storage temperature is typically between 10ºC to 25ºC or below 30ºC.