Verifica M Od 1000 Tab

VERIFICA M OD 1000 Tablet is a combination medication manufactured by Lupin Ltd. used for the management of type 2 diabetes mellitus.

Name

• Brand Name: VERIFICA M OD 1000 TABLET
• Common Name: Vildagliptin and Metformin combination.

Composition

• Active Ingredients: Each tablet contains Metformin 1000 mg and Vildagliptin 100 mg.

Uses

VERIFICA M OD 1000 TABLET is prescribed for adult patients with type 2 diabetes mellitus to manage high blood sugar levels. It is particularly indicated when diet and exercise alone, or other antidiabetic medicines (like insulin or sulfonylureas), do not adequately control blood sugar. This medication helps prevent serious complications of diabetes such as kidney damage, vision loss (retinopathy), nerve damage (neuropathy), diabetic foot ulcer, and may reduce the risk of heart attack or stroke.

Dosage and Administration

The dosage of VERIFICA M OD 1000 TABLET is determined by a physician based on the patient's condition, blood sugar levels, and other concurrent medications. It is generally advised to take it at the same time each day to maintain consistent blood sugar levels. The tablet should be swallowed whole with a glass of water and should not be crushed, chewed, or broken. Taking it with meals can help reduce stomach upset.

Side Effects

Common side effects include:

• Diarrhea
• Stomach pain / Abdominal pain
• Nausea and Vomiting
• Loss of appetite
• Metallic taste
• Headache
• Low blood glucose (hypoglycemia), characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth, and skin.
• Joint pain, tiredness
• Constipation
• Swollen hands, ankles, or feet (oedema)
• Nasopharyngitis and upper respiratory tract infection
• Decreased vitamin B12 levels with long-term use

Serious side effects, though rare, include:

• Lactic acidosis (symptoms include vomiting, stomach pain, decreased heartbeat, difficulty breathing, muscle cramps, general weakness with severe tiredness, or reduced body temperature).
• Inflamed pancreas (severe and persistent pain in the abdomen with or without nausea or vomiting).
• Serious skin reaction known as bullous pemphigoid.

Precautions

• Allergies: Avoid if allergic to vildagliptin, metformin, or any other ingredients.
• Kidney/Liver/Heart Problems: Inform your doctor if you have kidney, liver, or heart problems, as caution is advised. It is not recommended for moderate to severe kidney problems or liver disease. Regular monitoring of kidney function is essential.
• Pregnancy and Breastfeeding: Not recommended for pregnant women; use only if advised by a doctor. It is probably unsafe during breastfeeding as components may pass into breast milk.
• Alcohol Consumption: Avoid alcohol as it can increase the risk of lactic acidosis and lower blood glucose.
• Children and Adolescents: Not suitable for use in individuals under 18 years of age.
• Elderly Patients: Use with caution in elderly patients (65 years and above), especially with impaired kidney function.
• Medical Conditions: Inform your doctor if you have type 1 diabetes mellitus, diabetic ketoacidosis, congestive heart failure, metabolic acidosis, pancreatitis, or low vitamin B12 levels.
• Drug Interactions: Inform your doctor about all medicines you are taking, especially glucocorticoids, beta-2 agonists, diuretics, NSAIDs, ACE inhibitors, thiazide diuretics, corticosteroids, calcium channel blockers, and thyroid products, as they can interact with VERIFICA M OD 1000 TABLET.
• Driving: May affect ability to drive due to potential low or high blood sugar levels. Carry sugar/juice to manage hypoglycemia while driving.
• Stopping Medication: Do not stop taking the medicine abruptly without consulting your doctor, as it can lead to a sudden rise in blood glucose levels.

Storage

Store in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it away from children and pets. Store below 30°C. Dispose of any unused medicine safely.

Here are the most frequently asked questions about VERIFICA M OD 1000 Tablet:

What is VERIFICA M OD 1000 Tablet used for?

VERIFICA M OD 1000 Tablet is a combination medication primarily used to manage Type 2 diabetes mellitus in adults. It helps control high blood sugar levels when diet and exercise alone are not sufficient, or when treatment with either metformin or vildagliptin alone is not effective. This helps prevent serious complications of diabetes such as kidney damage, vision loss, nerve problems, and may reduce the risk of heart attack or stroke.

How does VERIFICA M OD 1000 Tablet work?

This medicine contains two active ingredients: Metformin and Vildagliptin. Metformin works by lowering the production of glucose in the liver, delaying the absorption of glucose from the intestines, and increasing the body's sensitivity to insulin. Vildagliptin, a DPP-4 inhibitor, increases the release of insulin from the pancreas and decreases the hormones that raise blood sugar levels (glucagon). Together, they provide better control of blood sugar by addressing both insulin resistance and insulin secretion issues.

What is the usual dosage for VERIFICA M OD 1000 Tablet?

The dosage of VERIFICA M OD 1000 Tablet is determined by your doctor based on your medical condition, blood sugar levels, and how you respond to treatment. It is typically taken with food at the same time each day to help reduce stomach upset and maintain consistent blood sugar levels. You should always follow your doctor's instructions precisely and not change your dose without consulting them.

What are the possible side effects of VERIFICA M OD 1000 Tablet?

Common side effects may include low blood sugar (hypoglycemia), diarrhea, nausea, vomiting, stomach pain, headache, and a metallic taste in the mouth. Hypoglycemia is more likely if taken with other diabetes medicines like insulin or sulfonylureas. A rare but serious side effect is lactic acidosis, which requires immediate medical attention and can manifest as vomiting, stomach pain, decreased heartbeat, difficulty breathing, or muscle cramps.

Is VERIFICA M OD 1000 Tablet safe during pregnancy or breastfeeding?

VERIFICA M OD 1000 Tablet is generally not recommended during pregnancy or breastfeeding. Limited human data suggests potential risks to the developing baby or the possibility of the drug passing into breast milk. It is crucial to consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding, as they will weigh the benefits against potential risks and may suggest alternative treatments.

Can VERIFICA M OD 1000 Tablet be taken with other medications?

VERIFICA M OD 1000 Tablet can interact with certain medications. Inform your doctor about all medicines, supplements, or herbal products you are taking to avoid possible interactions. Some medications that may interact include glucocorticoids (e.g., dexamethasone), beta-2 agonists (e.g., albuterol), diuretics (e.g., hydrochlorothiazide), NSAIDs (e.g., ibuprofen), and ACE inhibitors (e.g., enalapril).

What precautions should be taken while taking VERIFICA M OD 1000 Tablet?

This medicine is not suitable for individuals with Type 1 diabetes or diabetic ketoacidosis. Caution is advised if you have kidney, liver, or heart problems, or a history of pancreatic issues. Avoid alcohol consumption while on this medication, as it can increase the risk of lactic acidosis. Your doctor will monitor your kidney function and blood sugar levels regularly during treatment, and long-term use may require monitoring for Vitamin B12 deficiency.

What happens if a dose of VERIFICA M OD 1000 Tablet is missed?

If you miss a dose of VERIFICA M OD 1000 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should VERIFICA M OD 1000 Tablet be stored?

VERIFICA M OD 1000 Tablet should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it in its original container, tightly closed, and out of the sight and reach of children and pets. Do not use expired medicine, and discard any unused medicine properly.