Empagreat S 10mg Tab

EMPAGREAT S 10MG TABLET

Empagreat S 10mg Tablet is a prescription medication manufactured by Mankind Pharma Ltd., used for the management of type 2 diabetes mellitus. This combination medicine aids in improving blood sugar control when diet and exercise alone are insufficient. It also helps reduce the risk of diabetes-related complications such as heart disease and kidney problems.

Composition

• Active Ingredients: Each tablet contains Empagliflozin 10mg and Sitagliptin 100mg.
  • Empagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that works by helping the kidneys remove excess sugar from the body through urine.
  • Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps the body release more insulin when blood sugar is high and reduces the amount of sugar produced by the liver.

Uses

• Treatment of type 2 diabetes mellitus in adults.
• Improvement of glycemic (blood sugar) control.
• Reduction of cardiovascular risk in patients with type 2 diabetes.
• Protection of kidney function in diabetic patients.

Dosage and Administration Empagreat S 10mg Tablet should be taken as directed by your doctor.

• Typically, it is taken orally once daily.
• It can be taken with or without food, but it is better to take it at a fixed time.
• Swallow the tablet whole with water; do not chew, crush, or break it.
• Never change the dose without consulting your doctor.

Side Effects Common side effects may include:

• Urinary tract infections (UTIs)
• Fungal infections, particularly genital yeast infections
• Upper respiratory tract infections
• Headache
• Increased urination and thirst
• Constipation
• Rash or itching

Serious side effects, though rare, can include ketoacidosis, dehydration, and kidney problems. Low blood sugar (hypoglycemia) can also occur, especially when taken with other diabetes medicines like insulin or sulfonylureas.

Precautions

• Inform your doctor about any history of kidney or liver problems, urinary tract infections, or heart conditions.
• Not recommended for people with type 1 diabetes or diabetic ketoacidosis.
• Use with caution in older adults and those who are dehydrated or on diuretics, as it may increase the risk of low blood pressure.
• Avoid excessive alcohol consumption while taking this medicine, as it can lower blood sugar and increase the risk of lactic acidosis.
• Pregnant and breastfeeding women should consult their doctor before taking this medicine, as it is generally not recommended.
• Inform your doctor about all other medicines, supplements, or herbals you are currently taking to avoid possible interactions.

Storage Store below 30°C. Keep in a cool, dry place, away from direct sunlight, and out of reach of children and pets.

EMPAGREAT S 10MG TAB is a medication used to manage type 2 diabetes mellitus. It is a combination of two active ingredients: Empagliflozin (10 mg) and Sitagliptin (100 mg).

Here are some frequently asked questions about EMPAGREAT S 10MG TAB:

What is EMPAGREAT S 10MG TAB used for?

EMPAGREAT S 10MG TAB is primarily used to control high blood sugar levels in adults with type 2 diabetes mellitus when diet and exercise alone are not sufficient. It helps to improve long-term diabetes management and can reduce the risk of diabetes-related complications such as nerve damage, kidney problems, and heart issues. The empagliflozin component also helps reduce the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease, and can lessen the risk of hospitalization for heart failure and worsening kidney disease. This medication is not for type 1 diabetes.

How does EMPAGREAT S 10MG TAB work?

EMPAGREAT S 10MG TAB contains two active ingredients that work in different ways to control blood sugar. Empagliflozin works by blocking the SGLT2 protein in the kidneys, which leads to increased removal of excess glucose from the body through urine, thereby lowering blood sugar levels. Sitagliptin works by increasing the production of insulin in the body after meals and decreasing the amount of sugar produced by the liver. Together, these two medicines provide comprehensive blood sugar control.

What is the usual dosage of EMPAGREAT S 10MG TAB?

The typical recommended dose for adults is one 10 mg tablet once daily in the morning. It can be taken with or without food. Your doctor may adjust the dose, potentially increasing it to 25 mg daily, if more blood sugar control is needed and the initial dose is well-tolerated. For children aged 10 years and older with type 2 diabetes, the starting dose is also 10 mg daily, which can be increased to 25 mg if necessary. Always follow your doctor's specific instructions for dosage and duration of treatment.

What are the possible side effects of EMPAGREAT S 10MG TAB?

Common side effects can include urinary tract infections (UTIs), genital fungal infections (such as vaginal yeast infections or penile infections), increased urination, thirst, headache, rash, itching, and constipation. More serious but less common side effects can include ketoacidosis (a dangerous buildup of acids in the blood, which can occur even with normal blood sugar), dehydration, low blood pressure, acute kidney injury, and a rare but serious genital infection called Fournier's gangrene. If taken with insulin or sulfonylureas, there is an increased risk of hypoglycemia (low blood sugar). Report any unusual or severe symptoms to your healthcare provider.

Is EMPAGREAT S 10MG TAB safe during pregnancy or breastfeeding?

No, EMPAGREAT S 10MG TAB is generally not recommended during pregnancy, especially during the middle and final months, as it may harm the unborn baby and affect kidney development. For breastfeeding mothers, this medicine is also considered probably unsafe. It is not known whether the components pass into human breast milk, but animal studies suggest they may, raising concerns about potential effects on infant kidney development. Always consult your doctor for safer alternatives if you are pregnant, planning to become pregnant, or breastfeeding.

Can EMPAGREAT S 10MG TAB be taken with other medications?

EMPAGREAT S 10MG TAB can be taken alone or in combination with other diabetes medications. However, it's important to inform your doctor about all other medications and supplements you are taking, as certain interactions can occur. For instance, taking it with diuretics (water pills) or blood pressure-lowering medications may increase the risk of dehydration and low blood pressure. Concomitant use with insulin or sulfonylureas can increase the risk of hypoglycemia (low blood sugar), and your doctor may need to adjust the doses of these medications.

What precautions should be taken while taking EMPAGREAT S 10MG TAB?

Do not stop taking EMPAGREAT S 10MG TAB without consulting your doctor, as this can lead to a sudden increase in blood sugar levels and complications. It is important to stay well-hydrated, especially if you experience vomiting, diarrhea, fever, or are unable to eat or drink normally, as there is a risk of dehydration. Avoid excessive alcohol consumption, as it can lower blood sugar, increase the risk of dehydration, and raise the risk of a serious condition called lactic acidosis or ketoacidosis. Inform your doctor if you have kidney or liver problems, a history of pancreatitis, or recurrent urinary tract infections. Due to the potential for dizziness or sleepiness, exercise caution when driving or operating machinery until you know how the medicine affects you. Maintain good genital hygiene to reduce the risk of infections.

What happens if a dose of EMPAGREAT S 10MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should EMPAGREAT S 10MG TAB be stored?

Store EMPAGREAT S 10MG TAB in a cool, dry place, away from direct sunlight. Keep it out of reach of children and pets. The recommended storage temperature is below 30°C.