Tenepure M 1000 Tab

TENEPURE M 1000 Tablet

TENEPURE M 1000 Tablet is a medication prescribed for the management of type 2 diabetes mellitus in adults. It is manufactured by Torrent Pharmaceuticals Ltd..

• Composition: Each tablet contains Metformin 1000mg and Teneligliptin 20mg.

• Uses: This combination medicine is used to treat type 2 diabetes mellitus by improving glycemic control. It works by decreasing liver glucose production, lowering intestinal glucose uptake, improving insulin sensitivity, and increasing insulin levels while reducing glucagon levels in the body. It is often prescribed when diet and exercise alone, or metformin alone, are insufficient to regulate blood sugar levels.

• Dosage and Administration: TENEPURE M 1000 Tablet should be taken orally as prescribed by a physician, usually once daily with food to minimize stomach upset. The tablet should be swallowed whole and not crushed, chewed, or broken.

• Side Effects: Common side effects may include nausea, vomiting, diarrhea, headache, stomach ache, respiratory infection, weight gain, sweating, and hypoglycemia (low blood sugar), especially when used with insulin or sulfonylurea. Serious but rare side effects include lactic acidosis and potential Vitamin B12 deficiency with long-term use.

• Precautions:

  • Contraindications: Avoid use if allergic to any components, or in cases of severe kidney or liver impairment, congestive heart failure, lactic acidosis, diabetic ketoacidosis, type 1 diabetes, or diabetic coma.
  • Warnings: Inform your doctor if you are pregnant, breastfeeding, or have pre-existing conditions such as heart problems, severe infection, or severe trauma. Excessive alcohol consumption should be avoided due to an increased risk of lactic acidosis. Caution is advised while driving or operating heavy machinery if vision problems occur.
  • Interactions: Inform your doctor about all other medications, herbal preparations, and supplements you are taking, as interactions can occur with medicines affecting blood sugar levels, NSAIDs, verapamil, rifampicin, and Olaparib.

• Storage: Store in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep out of sight and reach of children.

TENEPURE M 1000 TAB is a medication used to manage Type 2 Diabetes Mellitus. It is a combination of Teneligliptin (20 mg) and Metformin Hydrochloride (1000 mg).

What is TENEPURE M 1000 TAB used for?

TENEPURE M 1000 TAB is primarily used for the management of Type 2 Diabetes Mellitus in adults. It is prescribed when diet and exercise alone, or treatment with metformin alone, have not been sufficient to control blood sugar levels. This medication helps to lower high blood sugar and improve blood sugar control, which can prevent or delay serious complications associated with diabetes, such as kidney damage, eye problems, nerve issues, heart disease, and stroke.

How does TENEPURE M 1000 TAB work?

This medicine contains two active ingredients that work in different ways to control blood sugar. Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the levels of natural substances called incretin hormones in the body. These hormones help the pancreas release more insulin when blood sugar levels are high and decrease the amount of glucagon, thereby lowering blood sugar, especially after meals. Metformin is a biguanide that primarily works by reducing the production of glucose in the liver, decreasing the absorption of glucose from the intestines, and improving the body's sensitivity to insulin, allowing cells to absorb and utilize glucose more effectively.

What is the usual dosage for TENEPURE M 1000 TAB?

The usual recommended dose for adults with Type 2 Diabetes is one tablet orally once daily, preferably with meals to minimize stomach upset. Your doctor may adjust the dose based on your medical condition and response to treatment. It is important to swallow the tablet whole and not to crush, chew, or break it. Do not exceed the maximum recommended daily dose of 40 mg teneligliptin and 2000 mg metformin hydrochloride.

What are the possible side effects of TENEPURE M 1000 TAB?

Common side effects can include nausea, vomiting, diarrhea, headache, stomach ache or abdominal discomfort, respiratory infection, weight gain, sweating, palpitations, constipation, bloating, loss of appetite, and sometimes low blood sugar (hypoglycemia). A serious but rare side effect is lactic acidosis, which requires immediate medical attention and symptoms may include abdominal pain, muscle cramps, severe fatigue, vomiting, and difficulty breathing. The medication may also lower vitamin B12 levels with long-term use.

Is TENEPURE M 1000 TAB safe during pregnancy or breastfeeding?

The safety of Teneligliptin during pregnancy has not been established, and it should only be used if the potential benefit outweighs the potential risk to the fetus. Metformin is generally considered safe during pregnancy, but insulin is often preferred for maintaining blood glucose levels. For breastfeeding mothers, Teneligliptin should be avoided as it may pass into breast milk. While Metformin passes into breast milk in small amounts and is considered safe, it's recommended to monitor the infant for any signs of side effects like vomiting, diarrhea, or hypoglycemia. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can TENEPURE M 1000 TAB be taken with other medications?

TENEPURE M 1000 TAB can interact with several other medications. It is crucial to inform your doctor about all other medicines you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Potential interactions can occur with other anti-diabetic medications (like sulfonylureas or insulin), certain cationic drugs (e.g., amiloride, digoxin), furosemide, nifedipine, danazol, corticosteroids, thyroid hormones, beta-blockers, MAO inhibitors, iodine contrast media (used in X-rays), bronchodilators, diuretics, antifungals (like ketoconazole), antidepressants, antihypertensives, estrogens, oral contraceptives, and some anticonvulsants.

What precautions should be taken while taking TENEPURE M 1000 TAB?

Take this medicine with meals to help reduce gastrointestinal side effects. Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia (low blood sugar) and a serious condition called lactic acidosis. Inform your doctor if you have kidney, liver, or heart problems, severe infection, severe trauma, or if you are scheduled for surgery. Regular monitoring of blood sugar levels and kidney function is essential while on this medication. This medication is not suitable for Type 1 diabetes, diabetic ketoacidosis, or patients with severe uncontrollable diabetes or alcoholism.

What happens if a dose of TENEPURE M 1000 TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should TENEPURE M 1000 TAB be stored?

Store TENEPURE M 1000 TAB in a cool, dry place, away from direct sunlight, heat, and moisture. Keep it in its original container, tightly closed, and out of reach of children and pets.