Sitared Md Ir 500mg Tab

Sitared-MD IR 5/50/500 Tablet

Sitared-MD IR 5/50/500 Tablet is a medication prescribed for the management of Type 2 Diabetes Mellitus in adults. It is manufactured by Sun Pharmaceutical Industries Ltd..

• Composition: Each tablet contains a combination of three active ingredients: Dapagliflozin 5mg, Sitagliptin 50mg, and Metformin 500mg.

  • Dapagliflozin works by removing excess sugar from the body through urine.
  • Sitagliptin increases the levels of natural substances that lower blood sugar when it is high.
  • Metformin reduces sugar production by the liver and delays sugar absorption from the intestines, while also improving insulin sensitivity.

• Uses: This medicine is used to control high blood glucose levels in adults with Type 2 Diabetes Mellitus, particularly when diet, exercise, and other therapies are insufficient. It also helps in preventing diabetes-related complications such as kidney damage, vision loss, nerve problems, and may reduce cardiovascular risks.

• Dosage and Administration: Take Sitared-MD IR 5/50/500 Tablet as advised by your doctor, usually orally. It can be taken with or without food, but taking it with meals may help reduce gastrointestinal discomfort. The tablet should be swallowed whole with water and not crushed, broken, or chewed. It is recommended to take the medicine at the same time each day for optimal benefits.

• Side Effects: Common side effects include nausea, vomiting, abdominal pain, headache, diarrhea, stomach upset, nasal congestion, sore throat, genital fungal infections, nasopharyngitis (cold symptoms), and hypoglycemia (low blood sugar). Serious, though rare, side effects can include lactic acidosis, ketoacidosis, acute pancreatitis, and severe allergic reactions.

• Precautions: Sitared-MD IR 5/50/500 Tablet is not recommended during pregnancy or breastfeeding, or for patients with severe kidney disease, liver disease, heart failure, respiratory failure, Type 1 diabetes, or metabolic acidosis. Caution is advised for elderly patients and those with a history of urinary tract infections. Avoid excessive alcohol consumption, as it may increase the risk of lactic acidosis. Inform your doctor about all existing medical conditions and medications, including herbal supplements, to prevent potential drug interactions. Regular monitoring of blood sugar levels and kidney function is crucial during treatment.

• Storage: Store Sitared-MD IR 5/50/500 Tablet in a cool, dry place away from direct sunlight, at room temperature (below 25°C or 30°C). Keep it out of the sight and reach of children.

What is SITARED MD IR 500MG TAB used for?

SITARED MD IR 500MG TAB is used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It is typically prescribed as an adjunct to diet and exercise when blood sugar levels are not adequately controlled by other single-medicine therapies. This medication helps prevent serious diabetes-related complications such as kidney damage, vision loss, nerve problems, and cardiovascular risks.

How does SITARED MD IR 500MG TAB work?

SITARED MD IR 500MG TAB contains a combination of three active ingredients: Dapagliflozin, Sitagliptin, and Metformin, each working through a different mechanism to control blood sugar.

• Dapagliflozin is an SGLT2 inhibitor that works by causing the kidneys to remove excess glucose from the body through urine, thereby lowering blood glucose levels.
• Sitagliptin is a DPP-4 inhibitor that increases the levels of natural substances called incretins, which enhance the pancreas's ability to release more insulin when blood sugar is high and reduce sugar production by the liver.
• Metformin is a biguanide that decreases glucose production in the liver, reduces glucose absorption from the intestines, and improves the body's sensitivity to insulin.

What is the usual dosage for SITARED MD IR 500MG TAB?

The specific formulation "SITARED MD IR 5/50/500 Tablet" indicates 5mg Dapagliflozin, 50mg Sitagliptin, and 500mg Metformin. This medicine is typically taken orally, usually once or twice daily with meals to help reduce stomach upset. Your doctor will determine the appropriate dosage based on your medical condition, current diabetes regimen, and response to treatment. Do not crush, break, or chew the tablets, and do not discontinue the medication without your doctor's guidance.

What are the possible side effects of SITARED MD IR 500MG TAB?

Common side effects may include nausea, vomiting, stomach upset, diarrhea, headache, upper respiratory infection, and genital fungal infections. More serious, though rare, side effects include:

• Lactic Acidosis: A serious (sometimes fatal) condition caused by too much metformin build-up, more likely in older adults or those with kidney/liver disease, dehydration, heart failure, or heavy alcohol use. Symptoms can include severe drowsiness, rapid breathing, unusual muscle pain, and feeling cold in hands or feet.
• Pancreatitis: Inflammation of the pancreas, which can be severe. Symptoms include severe stomach pain that may spread to your back, with or without vomiting.
• Hypoglycemia (low blood sugar): Especially when used with other diabetes medications like sulfonylureas or insulin. Symptoms include headache, dizziness, weakness, confusion, irritability, hunger, fast heartbeat, and sweating.
• Kidney problems: Including acute kidney failure.
• Allergic reactions: Such as rash, hives, or swelling of the face, lips, tongue, and throat.
• Vitamin B12 deficiency: Can occur with long-term metformin use. If you experience any serious or worsening side effects, seek immediate medical attention.

Is SITARED MD IR 500MG TAB safe during pregnancy or breastfeeding?

SITARED MD IR 500MG TAB is generally not recommended during pregnancy or breastfeeding. There is limited information on the effects of sitagliptin on a developing baby, and it is unknown how much of it passes into breast milk. If you are pregnant, planning to become pregnant, or breastfeeding, you should discuss alternative, safer treatments with your doctor.

Can SITARED MD IR 500MG TAB be taken with other medications?

This medication can interact with other drugs. It's crucial to inform your doctor about all prescription, non-prescription, and herbal supplements you are taking. Interactions can occur with:

• Other antidiabetic agents: Such as insulin or sulfonylureas, which may increase the risk of low blood sugar (hypoglycemia).
• Diuretics (water pills): Like furosemide and hydrochlorothiazide, which may increase the risk of dehydration and lactic acidosis.
• Carbonic anhydrase inhibitors: May increase the risk of lactic acidosis.
• Cimetidine, digoxin, dolutegravir, morphine, phenytoin, quinine, ranitidine, ranolazine, vandetanib: These and other cationic drugs can potentially interact with metformin.
• Iodinated contrast agents: Used in certain X-ray procedures. You may need to temporarily stop taking this medication before and after such procedures.
• Alcohol: Excessive alcohol intake should be avoided as it increases the risk of lactic acidosis and low blood sugar.

What precautions should be taken while taking SITARED MD IR 500MG TAB?

Several precautions are important while taking this medicine:

• Kidney Function: Your doctor will monitor your kidney function regularly before and during treatment, as impaired kidney function increases the risk of serious side effects like lactic acidosis. This medication is contraindicated in severe renal impairment.
• Lactic Acidosis: Be aware of the symptoms of lactic acidosis (e.g., severe weakness, rapid breathing, unusual muscle pain, feeling cold) and seek emergency medical help immediately if they occur. Risk factors include kidney/liver disease, dehydration, heart failure, heavy alcohol use, surgery, or contrast imaging.
• Pancreatitis: Report any sudden, severe abdominal pain to your doctor immediately.
• Dehydration: Ensure adequate fluid intake unless otherwise directed by your doctor, as dehydration can increase the risk of lactic acidosis.
• Stressful conditions: Illnesses (fever, infection), injury, or surgery can affect blood sugar control and may require temporary discontinuation of the medication.
• Type 1 Diabetes: This medicine is not for patients with type 1 diabetes.

What happens if a dose of SITARED MD IR 500MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.

How should SITARED MD IR 500MG TAB be stored?

Store the medicine in a cool and dry place, away from direct light and moisture, and out of the reach of children. The recommended storage temperature is generally not above 25°C. Keep it in its original container.