Metlong 500 Tablet

METLONG 500 TABLET

METLONG 500 TABLET, manufactured by Mankind Pharma Ltd., is an oral anti-diabetic medication used to manage blood glucose levels.

• Composition:

  • Active Ingredient: Metformin Hydrochloride 500 mg.

• Uses:

  • Type 2 Diabetes Mellitus: Primarily prescribed to control high blood sugar levels when diet and exercise alone are insufficient. It works by decreasing glucose production in the liver, improving the body's response to insulin, and reducing glucose absorption from the intestines.
  • Polycystic Ovary Syndrome (PCOS): Also used in women to manage symptoms associated with PCOS, such as insulin resistance, irregular periods, and weight gain, by improving insulin sensitivity.
  • Helps prevent serious complications of diabetes, including kidney damage, blindness, nerve damage, stroke, and heart attack.

• Dosage and Administration:

  • Take as advised by your physician, usually with or just after a meal to minimize stomach discomfort.
  • Swallow the tablet whole with a glass of water; do not crush, break, or chew it.
  • Maintain a consistent daily schedule for optimal effectiveness.

• Side Effects:

  • Common: Nausea, vomiting, diarrhea, abdominal pain/discomfort, loss of appetite, and a metallic taste in the mouth. These usually resolve over time.
  • Serious (Rare): Lactic acidosis (characterized by muscle pain, severe tiredness, difficulty breathing, stomach pain with cramps), and Vitamin B12 deficiency with long-term use.
  • Hypoglycemia (low blood sugar) may occur, especially when combined with other anti-diabetic drugs, alcohol, or skipped meals.

• Precautions:

  • Do not use if allergic to Metformin or its components.
  • Inform your doctor about any history of kidney, liver, or heart problems, severe infections, or dehydration.
  • Not recommended in severe kidney or liver disease.
  • Avoid or limit alcohol consumption due to increased risk of lactic acidosis and hypoglycemia.
  • Consult your doctor if pregnant, planning a pregnancy, or breastfeeding.
  • Monitor blood sugar levels and kidney function regularly.
  • Interactions may occur with other medications, including insulin, sulfonylureas, cationic drugs (e.g., amiloride, digoxin), and carbonic anhydrase inhibitors (e.g., topiramate).

• Storage:

  • Store in a cool, dry place, away from direct sunlight.
  • Keep out of sight and reach of children.
  • Maintain storage temperature between 10ºC to 25ºC or below 30ºC.

What is METLONG 500 TABLET used for?

METLONG 500 TABLET contains Metformin and is primarily used to treat Type 2 Diabetes Mellitus, especially in individuals who are overweight and whose blood sugar levels are not adequately controlled by diet and exercise alone. It can be used by itself or in combination with other anti-diabetic medications, including insulin. Additionally, it is prescribed for women with Polycystic Ovary Syndrome (PCOS) to help improve insulin sensitivity, regulate menstrual cycles, and reduce symptoms.

How does METLONG 500 TABLET work?

METLONG 500 TABLET, containing Metformin, works by several mechanisms to lower blood glucose levels. It reduces the amount of glucose produced by the liver, decreases the absorption of glucose from the intestines into the bloodstream, and increases the body's sensitivity to insulin, allowing cells to absorb and utilize glucose more effectively.

What is the usual dosage for METLONG 500 TABLET?

For adults, the typical starting dosage for immediate-release metformin (like METLONG 500 TABLET) is 500 mg twice daily, taken with morning and evening meals, or 850 mg once daily with the morning meal. Your doctor may gradually increase the dose, usually by 500 mg per week or 850 mg every two weeks, until blood sugar is controlled. The maximum daily dose is generally not more than 2550 mg, which should be divided into 2 or 3 doses if it exceeds 850 mg. It is important to take this medicine with meals to help reduce potential side effects.

What are the possible side effects of METLONG 500 TABLET?

Common side effects include diarrhea, nausea, vomiting, stomach pain, gas, bloating, heartburn, headache, a metallic taste in the mouth, and fatigue. These often occur when starting the medication and usually improve over time.

Serious but rare side effects can include lactic acidosis (a dangerous buildup of lactic acid, which is a medical emergency with symptoms like extreme tiredness, trouble breathing, and unusual muscle pain), and a deficiency in Vitamin B12 with long-term use.

Is METLONG 500 TABLET safe during pregnancy or breastfeeding?

Metformin is generally considered safe and effective to take during pregnancy for Type 2 diabetes and gestational diabetes, and it has a low risk of birth defects. It is also safe to take while breastfeeding, as only tiny amounts pass into breast milk and are not associated with side effects in breastfed babies. However, it is crucial to discuss the use of any medication during pregnancy or breastfeeding with your doctor.

Can METLONG 500 TABLET be taken with other medications?

Yes, METLONG 500 TABLET can be taken with other diabetes medications, including insulin. However, it can interact with certain medications. Inform your doctor about all medicines, supplements, and herbal preparations you are taking. Some drugs, such as certain diuretics (e.g., furosemide, hydrochlorothiazide), corticosteroids, carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide), cimetidine, and iodinated contrast media used for X-rays or CT scans, can interact with metformin and potentially increase the risk of side effects like lactic acidosis or affect blood sugar control. Your doctor may need to adjust doses or temporarily stop metformin for certain procedures.

What precautions should be taken while using METLONG 500 TABLET?

Avoid consuming alcohol while taking METLONG 500 TABLET as it can significantly increase the risk of lactic acidosis, a serious side effect. It is important to maintain good hydration, especially if you experience severe diarrhea, vomiting, or fever. Your doctor will regularly monitor your kidney function (at least yearly) and may check your vitamin B12 levels if you are on long-term treatment. Always inform your doctor if you have kidney or liver problems, heart conditions, or are scheduled for surgery or imaging tests involving dye, as these may require temporary discontinuation of the medication.

What happens if a dose of METLONG 500 TABLET is missed?

If you miss a dose of METLONG 500 TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should METLONG 500 TABLET be stored?

METLONG 500 TABLET should be stored in a closed container at room temperature, ideally between 20-25°C (68-77°F). Keep it away from excessive heat, moisture, and direct light. Ensure it is kept out of the reach of children.