Zadonase Tablet (10 Tab)

ZADONASE TABLET (10 TAB) by ALKEM LABORATORIES LTD

Zadonase Tablet is an anti-allergic medication prescribed to manage various allergy symptoms. It is manufactured by Alkem Laboratories Ltd.

• Composition: Zadonase Tablet contains a combination of two active ingredients: Montelukast (10 mg) and Fexofenadine (120 mg). Montelukast is a leukotriene receptor antagonist, while Fexofenadine is an antihistamine.

• Uses: This medicine is primarily used to treat allergic symptoms such as sneezing, runny nose, congestion, stuffy nose, and watery eyes. It is effective for managing seasonal or perennial allergic rhinitis. Zadonase Tablet also helps alleviate chronic hives (urticaria) by relieving itching and swelling. Additionally, it can be used for asthma management to prevent asthma attacks and reduce inflammation in the airways, improving breathing and reducing wheezing in asthma patients.

• Dosage and Administration: Zadonase Tablet should be taken exactly as prescribed by a doctor. It can be taken with or without food, typically once daily. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. The dosage and duration of treatment depend on the patient's condition and response to the medication.

• Side Effects: Common side effects may include drowsiness, headache, skin rash, diarrhea, nausea, vomiting, dizziness, and fever. Some individuals might also experience dry mouth or fatigue. If these side effects persist or worsen, medical consultation is advised. Rare, but serious side effects can include severe allergic reactions, difficulty breathing, or severe dizziness/fainting.

• Precautions:

  • Allergies: Do not take Zadonase Tablet if you are allergic to Montelukast, Fexofenadine, or any other components of the tablet.
  • Pregnancy and Breastfeeding: Consult a doctor before using this medicine if pregnant or breastfeeding.
  • Liver and Kidney Conditions: Inform your doctor if you have any liver or kidney problems, as dose adjustments or monitoring may be necessary.
  • Alcohol: Avoid consuming alcohol while taking Zadonase Tablet, as it may increase drowsiness and dizziness.
  • Driving and Operating Machinery: This medication may cause drowsiness or dizziness, so caution is advised when driving or operating machinery until you know how the medicine affects you.
  • Drug Interactions: Maintain at least a 2-hour gap between Zadonase Tablet and indigestion remedies containing magnesium and aluminum, as they can reduce the absorption of Zadonase Tablet. Certain fruit juices, such as apple, orange, or grapefruit, should be avoided as they may reduce the drug's effectiveness.
  • Children: Zadonase Tablet is generally not recommended for children below 12 years of age.

• Storage: Store Zadonase Tablet in a cool and dry place, away from direct sunlight. Keep it out of sight and reach of children. It should be stored at temperatures between 10ºC to 25ºC or below 30ºC.

Zadonase Tablet, manufactured by Alkem Laboratories Ltd, is a combination medication containing Montelukast and Fexofenadine. It is primarily used to manage and relieve symptoms associated with allergic conditions.

Here are some frequently asked questions about Zadonase Tablet:

What is Zadonase Tablet used for?

Zadonase Tablet is used to treat various allergy symptoms, including sneezing, runny nose, congestion, stuffy nose, and watery eyes. It is effective for conditions like seasonal or perennial allergic rhinitis, and it also helps manage chronic hives (urticaria). The medicine can also help minimize nocturnal symptoms such as coughing, nasal congestion, and breathing difficulty, thereby improving sleep quality.

How does Zadonase Tablet work?

Zadonase Tablet combines two active ingredients: Fexofenadine and Montelukast. Fexofenadine is an antihistamine that works by blocking the effects of histamine, a chemical in the body responsible for causing allergic reactions. Montelukast is a leukotriene receptor antagonist that blocks the action of leukotrienes, which are chemicals released from the lungs that cause inflammation, increased mucus production, and narrowing of the airways. Together, these ingredients reduce inflammation, mucus production, and airway constriction caused by allergies.

What is the usual dosage of Zadonase Tablet?

Zadonase Tablet is typically taken once daily, with or without food, as advised by your doctor. The tablet should be swallowed whole with a glass of water and should not be crushed, chewed, or broken. The exact dosage and duration of treatment will depend on your condition and how you respond to the medication. It's important to follow your doctor's instructions carefully and not exceed the prescribed dose.

What are the possible side effects of Zadonase Tablet?

Common side effects of Zadonase Tablet may include drowsiness, headache, nausea, vomiting, diarrhea, skin rash, dizziness, and flu-like symptoms. If these side effects persist or worsen, it's advisable to consult your doctor.

Is Zadonase Tablet safe during pregnancy or breastfeeding?

If you are pregnant or planning to become pregnant, it is crucial to consult your doctor before using Zadonase Tablet. The safety of Zadonase Tablet during pregnancy is unknown, and it should generally be avoided unless clearly needed and the potential benefits outweigh the risks. Similarly, if you are breastfeeding, it is advisable to consult your doctor, as it is unknown if the medication is excreted in human milk.

Can Zadonase Tablet be taken with other medications or substances?

Certain medications can interact with Zadonase Tablet, including antifungal medications (e.g., Fluconazole, Ketoconazole), antibiotics (e.g., Clarithromycin, Erythromycin), antidepressants (e.g., Amitriptyline, Fluoxetine), anticoagulants (e.g., Warfarin, Heparin), and anti-seizure medications (e.g., Carbamazepine, Phenobarbital). It is important to inform your doctor about all other medicines, supplements, or herbal products you are currently taking to avoid potential drug interactions.

You should also avoid consuming alcohol while taking Zadonase Tablet, as it may increase the risk of drowsiness and dizziness. Additionally, avoid taking it with fruit juices (such as apple, orange, or grapefruit) as they might reduce the effectiveness of the drug.

What precautions should be taken while using Zadonase Tablet?

Inform your doctor if you have any liver or kidney problems, as dosage adjustments may be necessary. Zadonase Tablet can cause drowsiness or dizziness, so it is advisable to avoid driving or operating heavy machinery until you know how the medicine affects you. Do not use this medicine in children below 12 years of age without consulting a doctor, as its safety and effectiveness have not been established. It is also recommended to stop taking Zadonase Tablet at least three days before an allergy test, as it can affect the test results.

What happens if a dose of Zadonase Tablet is missed?

If you forget to take a dose of Zadonase Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Zadonase Tablet be stored?

Zadonase Tablet should be stored at room temperature, away from heat, direct sunlight, and moisture. Keep it out of sight and reach of children and pets to prevent accidental ingestion. Ensure that any unused or expired medicine is disposed of properly.