Taxim O 400 Mg Tablet ( 10 Tab )

TAXIM O 400 MG TABLET

TAXIM O 400 MG Tablet, manufactured by ALKEM LABORATORIES LTD., is an antibiotic primarily used to treat various bacterial infections.

• Name:

  • Brand Name: TAXIM O 400 MG Tablet
  • Common Name: Cefixime

• Composition:

  • Each film-coated tablet contains Cefixime (as trihydrate) equivalent to Anhydrous Cefixime 400 mg.

• Uses: TAXIM O 400 MG Tablet is a third-generation cephalosporin antibiotic prescribed for a range of bacterial infections. It works by preventing bacteria from forming their protective cell walls, thereby stopping their growth and killing them. It is not effective against viral infections like the common cold or flu. It is indicated for the treatment of:

  • Upper Respiratory Tract Infections (URTI): such as otitis media (ear infections), sinusitis, pharyngitis, and tonsillitis.
  • Lower Respiratory Tract Infections (LRTI): including bronchitis and pneumonia.
  • Urinary Tract Infections (UTI): such as cystitis, cystourethritis, and uncomplicated pyelonephritis.
  • Sexually Transmitted Infections: particularly uncomplicated gonorrhea.
  • Other infections: including typhoid fever and Shigella (which causes severe diarrhea).

• Dosage and Administration:

  • Adults and Children over 10 years or weighing more than 50 kg: The recommended adult dosage is 400 mg daily, given either as a single dose or in two divided doses (200 mg every 12 hours).
  • Course Duration: The usual course of treatment is 7 days, which may be extended up to 14 days if required.
  • Administration: The tablet should be swallowed whole with water. It can be taken with or without food, though taking it after food may help prevent nausea. It is best taken at the same time every day.
  • Missed Dose: If a dose is missed, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not double doses.
  • Renal Impairment: Dosage adjustment may be necessary for patients with severe kidney impairment.

• Side Effects: Most side effects are mild and transient.

  • Common Side Effects: Diarrhea, stomach pain, gas, heartburn, nausea, vomiting, and headache.
  • Serious Side Effects: Seek immediate medical attention if you experience severe allergic reactions (e.g., rash, itching, hives, swelling of the face, tongue, or throat, difficulty breathing), severe watery diarrhea (possibly with blood), stomach cramps, or signs of encephalopathy (convulsions, confusion, impairment of consciousness, movement disorders).

• Precautions:

  • Allergies: Contraindicated in patients with known hypersensitivity to cephalosporin antibiotics or any other components of the product. Use with caution in patients with a history of penicillin allergy due to potential cross-allergenicity.
  • Pregnancy and Breastfeeding: Should be used during pregnancy or by nursing mothers only if considered essential by the physician.
  • Medical Conditions: Inform your doctor if you have a history of liver disease, kidney problems, gastrointestinal diseases, or seizure disorders.
  • Drug Interactions: May interact with other medications, including oral contraceptive pills (reducing their effectiveness) and certain other antibiotics or vaccines.

• Storage: Store TAXIM O 400 MG Tablet in a tightly closed container at room temperature, away from excess heat, moisture, and direct light. Keep it out of the reach of children.

TAXIM O 400 MG TABLET FAQs

What is TAXIM O 400 MG TABLET used for?

TAXIM O 400 MG TABLET is an antibiotic medicine primarily used to treat various bacterial infections in the body. These include infections of the upper respiratory tract (e.g., ear infections like otitis media, tonsillitis, pharyngitis, sinusitis), lower respiratory tract (e.g., bronchitis, pneumonia), urinary tract (e.g., cystitis, cystourethritis, uncomplicated pyelonephritis, kidney infections), and sexually transmitted diseases like uncomplicated gonorrhea. It is not effective against viral infections such as the flu or common cold.

How does TAXIM O 400 MG TABLET work?

TAXIM O 400 MG TABLET contains Cefixime, which is a cephalosporin antibiotic. It works by preventing bacteria from forming their protective cell walls, which are essential for their survival. By inhibiting the synthesis of the bacterial cell wall, the medicine weakens and ultimately destroys the bacteria, stopping their growth and multiplication.

What is the usual dosage for TAXIM O 400 MG TABLET?

For adults and children over 10 years or weighing more than 50 kg, the recommended adult dosage is typically 200 mg to 400 mg daily. This can be given as a single dose or in two divided doses, depending on the severity of the infection. For uncomplicated cervical/urethral gonococcal infections, a single oral dose of 400 mg is usually recommended. It's crucial to follow your doctor's prescribed dosage and complete the full course of treatment, even if you start to feel better.

What are the possible side effects of TAXIM O 400 MG TABLET?

Common side effects can include nausea, vomiting, diarrhea, stomach pain, indigestion, gas, and heartburn. Some individuals may also experience headaches or dizziness. If these common side effects persist or worsen, you should consult your doctor. More serious, though less common, side effects can include severe allergic reactions (like skin rash, itching, swelling of face, lips, throat, or tongue, difficulty breathing), unusual bleeding or bruising, severe watery diarrhea (which could indicate pseudomembranous colitis), or seizures. Seek immediate medical attention if you experience severe side effects.

Is TAXIM O 400 MG TABLET safe during pregnancy or breastfeeding?

During pregnancy, TAXIM O 400 MG TABLET should be used only if clearly needed and strictly under a doctor's advice, as there is limited information on its effects in pregnant women. Animal studies have shown no risk to the fetus, but human data are not conclusive.

For breastfeeding mothers, it is generally advised to consider discontinuing nursing temporarily during treatment with this drug, as it is not known whether cefixime is excreted in human milk. If taken while breastfeeding, monitor the infant for diarrhea. It should only be used if considered essential by the physician.

Can TAXIM O 400 MG TABLET be taken with other medications?

TAXIM O 400 MG TABLET can interact with certain medications. For example, it may increase the effect of anticoagulants like warfarin, potentially leading to increased bleeding. It can also interact with certain anti-epileptics like carbamazepine, increasing its effects. Combining it with alcohol or alcohol-containing medicines can increase the severity of side effects such as sweating, headache, increased heartbeat, and skin redness. It's important to inform your doctor about all other medicines, herbal preparations, and supplements you are currently taking to avoid potential interactions.

What precautions should be taken when using TAXIM O 400 MG TABLET?

Precautions include:

• Allergies: Do not take if you are allergic to cefixime or any other cephalosporin antibiotics, or if you have a history of hypersensitivity to penicillin.
• Kidney/Liver Disease: Use with caution if you have kidney or liver disease, as dose adjustments may be necessary.
• Gastrointestinal Issues: Be cautious if you have a history of gastrointestinal diseases, especially colitis, as diarrhea can be a significant side effect.
• Driving/Operating Machinery: While generally safe, if you experience dizziness, confusion, or fits, avoid driving or operating heavy machinery.
• Antibiotic Resistance: Do not use this antibiotic for viral infections, as inappropriate use can lead to antibiotic resistance.
• Lab Tests: Inform your doctor that you are taking TAXIM O 400 MG TABLET before undergoing urine glucose tests (may cause false positives) or Coombs' test (may cause false positives).
• Cholera Vaccine: Avoid the cholera vaccine if you have taken TAXIM O 400 MG TABLET within 14 days before vaccination.

What happens if a dose of TAXIM O 400 MG TABLET is missed?

If you miss a dose of TAXIM O 400 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase the risk of side effects.

How should TAXIM O 400 MG TABLET be stored?

TAXIM O 400 MG TABLET should be stored in a cool, dry place, typically below 25°C or 30°C. It should be protected from light and moisture and kept in its original packaging. Ensure it is kept out of the reach of children and pets.